(Q34161890)

31 July 2017

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title

The proofreading 3'-->5' exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis (English)

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31 July 2017

2

Kristin A Eckert

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31 July 2017

Vineeta Khare

1

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31 July 2017

language of work or name

English

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publication date

1 December 2002

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31 July 2017

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31 July 2017

volume

510

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31 July 2017

issue

1-2

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31 July 2017

page(s)

45-54

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Mammalian DNA mismatch repair

31 July 2017

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1 reference

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DNA mismatch repair and genetic instability

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The 3' 5' exonucleases

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Eukaryotic DNA Polymerases

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A conserved 3'----5' exonuclease active site in prokaryotic and eukaryotic DNA polymerases

7 January 2021

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The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction

7 January 2021

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Structure-function analysis of 3'-->5'-exonuclease of DNA polymerases

7 January 2021

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Conformational coupling in DNA polymerase fidelity

7 January 2021

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Proofreading of DNA polymerase eta-dependent replication errors

7 January 2021

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Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

7 January 2021

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Structure of the replicating complex of a pol alpha family DNA polymerase

7 January 2021

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Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase.

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DNA polymerase mutagenic bypass and proofreading of endogenous DNA lesions.

7 January 2021

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Effect of single DNA lesions on in vitro replication with DNA polymerase III holoenzyme. Comparison with other polymerases

7 January 2021

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Hydrophobic interactions in the hinge domain of DNA polymerase beta are important but not sufficient for maintaining fidelity of DNA synthesis

7 January 2021

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Alkylation-induced frameshift mutagenesis during in vitro DNA synthesis by DNA polymerases alpha and beta

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The 3' --> 5' exonuclease of T4 DNA polymerase removes premutagenic alkyl mispairs and contributes to futile cycling at O6-methylguanine lesions

7 January 2021

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Development and use of an in vitro HSV-tk forward mutation assay to study eukaryotic DNA polymerase processing of DNA alkyl lesions

7 January 2021

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DNA replication fidelity with 8-oxodeoxyguanosine triphosphate.

7 January 2021

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Production of UV-induced frameshift mutations in vitro by DNA polymerases deficient in 3'-->5' exonuclease activity

7 January 2021

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Action of mitochondrial DNA polymerase gamma at sites of base loss or oxidative damage

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On the mechanism of preferential incorporation of dAMP at abasic sites in translesional DNA synthesis. Role of proofreading activity of DNA polymerase and thermodynamic characterization of model template-primers containing an abasic site

7 January 2021

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3'-5' Exonucleolytic activity of DNA polymerases: structural features that allow kinetic discrimination between ribo- and deoxyribonucleotide residues

7 January 2021

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High-resolution structure of a mutagenic lesion in DNA

7 January 2021

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Why do O6-alkylguanine and O4-alkylthymine miscode? The relationship between the structure of DNA containing O6-alkylguanine and O4-alkylthymine and the mutagenic properties of these bases

7 January 2021

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In vitro selection of sequence contexts which enhance bypass of abasic sites and tetrahydrofuran by T4 DNA polymerase holoenzyme.

7 January 2021

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Quantitative measurement of translesion replication in human cells: evidence for bypass of abasic sites by a replicative DNA polymerase

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7 January 2021

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Escherichia coli DNA polymerase III can replicate efficiently past a T-T cis-syn cyclobutane dimer if DNA polymerase V and the 3' to 5' exonuclease proofreading function encoded by dnaQ are inactivated

7 January 2021

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Inactivation of DNA proofreading obviates the need for SOS induction in frameshift mutagenesis

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7 January 2021

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DNA polymerase epsilon links the DNA replication machinery to the S phase checkpoint

7 January 2021

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Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint

7 January 2021

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Recombinational DNA repair of damaged replication forks in Escherichia coli: questions

7 January 2021

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Rescue of stalled replication forks by RecG: simultaneous translocation on the leading and lagging strand templates supports an active DNA unwinding model of fork reversal and Holliday junction formation

7 January 2021

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Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice

7 January 2021

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Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0027-5107(02)00251-8

1 reference

31 July 2017

1 reference