(Q34163470)

31 July 2017

title

Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility (English)

1 reference

31 July 2017

Jian-Hua Mao

5

0 references

author name string

Jesus Perez-Losada

1

1 reference

31 July 2017

Di Wu

2

1 reference

31 July 2017

Reyno DelRosario

3

1 reference

31 July 2017

Allan Balmain

4

1 reference

31 July 2017

language of work or name

English

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publication date

13 February 2012

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31 July 2017

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31 July 2017

volume

7

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31 July 2017

issue

2

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31 July 2017

page(s)

e31301

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

13 February 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

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Cancer evolution and individual susceptibility

5 July 2018

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Genome-wide association studies of cancer

5 July 2018

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Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer

5 July 2018

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Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy

5 July 2018

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Finding the missing heritability of complex diseases

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Control of genomic instability and epithelial tumor development by the p53-Fbxw7/Cdc4 pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Genetic interactions between Pten and p53 in radiation-induced lymphoma development

5 July 2018

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Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human

5 July 2018

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The genetics and genomics of cancer

5 July 2018

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Genomic approaches to identification of tumour-susceptibility genes using mouse models.

5 July 2018

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Cancer as a complex genetic trait: tumor susceptibility in humans and mouse models

5 July 2018

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SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

5 July 2018

1 reference

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Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Detection of 1p and 19q loss in oligodendroglioma by quantitative microsatellite analysis, a real-time quantitative polymerase chain reaction assay

5 July 2018

1 reference

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A subset of skin tumor modifier loci determines survival time of tumor-bearing mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Distinct genetic loci control development of benign and malignant skin tumours in mice.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Rhabdomyosarcoma in children: epidemiologic study and identification of a familial cancer syndrome

5 July 2018

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Mutation and cancer: statistical study of retinoblastoma

5 July 2018

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Complexity of lung cancer modifiers: mapping of thirty genes and twenty-five interactions in half of the mouse genome.

5 July 2018

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Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031301

Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031301

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031301

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031301

Allele-specific Hras mutations and genetic alterations at tumor susceptibility loci in skin carcinomas from interspecific hybrid mice.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Epistatic interactions between skin tumor modifier loci in interspecific (spretus/musculus) backcross mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Measurement of DNA copy number at microsatellite loci using quantitative PCR analysis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278431

Preferential amplification ofAURKA 91A (Ile31) in familial colorectal cancers

28 October 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031301

10.1371/JOURNAL.PONE.0031301

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

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1 reference

31 July 2017

1 reference