(Q34165531)

31 July 2017

Spontaneous Irs1 passenger mutation linked to a gene-targeted SerpinB2 allele (English)

1 reference

31 July 2017

2

Karen L Mohlke

1 reference

31 July 2017

Randal J Westrick

1

1 reference

31 July 2017

Lindsey M Korepta

3

1 reference

31 July 2017

Angela Y Yang

4

1 reference

31 July 2017

Goujing Zhu

5

1 reference

31 July 2017

Sara L Manning

6

1 reference

31 July 2017

Mary E Winn

7

1 reference

31 July 2017

Kristiann M Dougherty

8

1 reference

31 July 2017

David Ginsburg

9

1 reference

31 July 2017

language of work or name

English

0 references

publication date

13 September 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

31 July 2017

107

1 reference

31 July 2017

39

1 reference

31 July 2017

16904-16909

1 reference

Analysis of genetic inheritance in a family quartet by whole-genome sequencing

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Cautionary insights on knockout mouse studies: the gene or not the gene?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

DNA repair in murine embryonic stem cells and differentiated cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Genomic copy number and expression variation within the C57BL/6J inbred mouse strain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Deficiency of plasminogen activator inhibitor-2 impairs nutritionally induced murine adipose tissue development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

The problem of passenger genes in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Murine models of vascular thrombosis (Eitzman series).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Tissue-specific roles of IRS proteins in insulin signaling and glucose transport

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

The undecided serpin. The ins and outs of plasminogen activator inhibitor type 2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Unexpected embryonic stem (ES) cell mutations represent a concern in gene targeting: lessons from "fierce" mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Embryonic stem cells and somatic cells differ in mutation frequency and type

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Insulin signaling pathways in time and space.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Myf-5 revisited: loss of early myotome formation does not lead to a rib phenotype in homozygous Myf-5 mutant mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Restored insulin-sensitivity in IRS-1-deficient mice treated by adenovirus-mediated gene therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Primer3 on the WWW for general users and for biologist programmers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Comprehensive mammalian genetics: history and future prospects of gene trapping in the mouse.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Ahr null alleles: distinctive or different?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

DNA sequence motifs are associated with aberrant homologous recombination in the mouse macrophage migration inhibitory factor (Mif) locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Intestinal physiology and pathology in gene-targeted mouse models of cystic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Long-range disruption of gene expression by a selectable marker cassette

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Biological and clinical aspects of plasminogen activator inhibitor type 2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Fibrinolysis in pregnancy: a study of plasminogen activator inhibitors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Gene targeting in embryonic stem cells scores a knockout in Stockholm.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012050107

Bidirectional transcriptional activity of PGK-neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012050107

Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012050107

SerpinB2 protection of retinoblastoma protein from calpain enhances tumor cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012050107

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012050107

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012050107

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012050107

Genetic modifiers of the insulin resistance phenotype in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012050107

Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012050107

Plasminogen activator inhibitor type 2 inhibits cell surface associated tissue plasminogen activator in vitro: potential receptor interactions.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947888

Direct estimates of human per nucleotide mutation rates at 20 loci causing Mendelian diseases

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20837540

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

SerpinB2 is an inducible host factor involved in enhancing HIV-1 transcription and replication

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20837540

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1012050107

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference