(Q34174771)

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Mechanism of intracellular cAMP sensor Epac2 activation: cAMP-induced conformational changes identified by amide hydrogen/deuterium exchange mass spectrometry (DXMS).

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Europe PubMed Central

PubMed publication ID

31 July 2017

Mechanism of intracellular cAMP sensor Epac2 activation: cAMP-induced conformational changes identified by amide hydrogen/deuterium exchange mass spectrometry (DXMS). (English)

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Europe PubMed Central

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31 July 2017

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Mark A White

3

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Sheng Li

1

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Europe PubMed Central

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31 July 2017

Tamara Tsalkova

2

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Europe PubMed Central

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31 July 2017

Fang C Mei

4

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Europe PubMed Central

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31 July 2017

Tong Liu

5

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31 July 2017

Daphne Wang

6

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31 July 2017

Virgil L Woods

7

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31 July 2017

Xiaodong Cheng

8

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31 July 2017

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17 March 2011

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31 July 2017

Journal of Biological Chemistry

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31 July 2017

286

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31 July 2017

20

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Europe PubMed Central

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31 July 2017

17889-17897

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Europe PubMed Central

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31 July 2017

Exchange protein directly activated by cyclic AMP isoform 2 is not a direct target of sulfonylurea drugs.

1 reference

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The interaction of Epac1 and Ran promotes Rap1 activation at the nuclear envelope

1 reference

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Epac: defining a new mechanism for cAMP action

1 reference

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Structural insights into glucan phosphatase dynamics using amide hydrogen-deuterium exchange mass spectrometry

1 reference

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Mechanism of Epac activation: structural and functional analyses of Epac2 hinge mutants with constitutive and reduced activities

1 reference

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Location of inhibitors bound to group IVA phospholipase A2 determined by molecular dynamics and deuterium exchange mass spectrometry

1 reference

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Direct spatial control of Epac1 by cyclic AMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093864

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Epac and PKA: a tale of two intracellular cAMP receptors

1 reference

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Neuronal AKAP150 coordinates PKA and Epac-mediated PKB/Akt phosphorylation.

1 reference

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Calcium binding rigidifies the C2 domain and the intradomain interaction of GIVA phospholipase A2 as revealed by hydrogen/deuterium exchange mass spectrometry

1 reference

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28 July 2018

Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state

1 reference

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Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis

1 reference

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Protein structure change studied by hydrogen-deuterium exchange, functional labeling, and mass spectrometry.

1 reference

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28 July 2018

Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac

1 reference

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28 July 2018

Cell cycle-dependent subcellular localization of exchange factor directly activated by cAMP.

1 reference

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28 July 2018

Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation

1 reference

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Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway

1 reference

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28 July 2018

cAMP-GEFII is a direct target of cAMP in regulated exocytosis

1 reference

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28 July 2018

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

1 reference

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A family of cAMP-binding proteins that directly activate Rap1

1 reference

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28 July 2018

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

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Pleckstrin's repeat performance: a novel domain in G-protein signaling?

1 reference

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28 July 2018

Determination of amide hydrogen exchange by mass spectrometry: a new tool for protein structure elucidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093864

28 July 2018

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224535

21 January 2018

Interplay between exchange protein directly activated by cAMP (Epac) and microtubule cytoskeleton

1 reference

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Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224535

21 January 2018

Critical role of the N-terminal cyclic AMP-binding domain of Epac2 in its subcellular localization and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224535

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Dynamic coupling between the SH2 domain and active site of the COOH terminal Src kinase, Csk.

1 reference

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21 January 2018

Mapping intersubunit interactions of the regulatory subunit (RIalpha) in the type I holoenzyme of protein kinase A by amide hydrogen/deuterium exchange mass spectrometry (DXMS).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224535

21 January 2018

Distinct interaction modes of an AKAP bound to two regulatory subunit isoforms of protein kinase A revealed by amide hydrogen/deuterium exchange

1 reference

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Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization.

1 reference

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Conformational analysis of Epac activation using amide hydrogen/deuterium exchange mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454623

12 December 2020

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Identifiers

10.1074/JBC.M111.224535

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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