(Q34178292)

English

Virulence Determinants of Avian H5N1 Influenza A Virus in Mammalian and Avian Hosts: Role of the C-Terminal ESEV Motif in the Viral NS1 Protein

scientific article published on August 4, 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Virulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: role of the C-terminal ESEV motif in the viral NS1 protein (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Virulence Determinants of Avian H5N1 Influenza A Virus in Mammalian and Avian Hosts: Role of the C-Terminal ESEV Motif in the Viral NS1 Protein (English)

1 reference

10.1128/JVI.00610-10

https://api.crossref.org/works/10.1128/JVI.00610-10

16 June 2024

influenza A virus

object named as

influenza A virus

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based on heuristic

inferred from title

Donata Kalthoff

3

object named as

Donata Kalthoff

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7

object named as

Martin Beer

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Europe PubMed Central

PubMed publication ID

31 July 2017

6

object named as

Achim D Gruber

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Florian Zielecki

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Ilia Semmler

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Daniel Voss

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Susanne Mauel

5

1 reference

Europe PubMed Central

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31 July 2017

Thorsten Wolff

8

1 reference

Europe PubMed Central

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31 July 2017

Achim D. Gruber

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686040

16 June 2024

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4 August 2010

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31 July 2017

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16 June 2024

http://jvi.asm.org/cgi/content/abstract/84/20/10708

online access status

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686040

16 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20686040/?tool=EBI

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686040

16 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20686040/pdf/?tool=EBI

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1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686040

16 June 2024

https://europepmc.org/articles/PMC2950580

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Europe PubMed Central

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686040

16 June 2024

https://europepmc.org/articles/PMC2950580?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686040

16 June 2024

https://doi.org/10.1128/jvi.00610-10

online access status

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686040

16 June 2024

https://journals.asm.org/doi/pdf/10.1128/JVI.00610-10

1 reference

10.1128/JVI.00610-10

https://api.crossref.org/works/10.1128/JVI.00610-10

16 June 2024

Journal of Virology

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

84

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

20

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

10708-10718

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Species-specific contribution of the four C-terminal amino acids of influenza A virus NS1 protein to virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Nucleolar localization of influenza A NS1: striking differences between mammalian and avian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication.

1 reference

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5 July 2018

Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Influenza viruses control the vertebrate type I interferon system: factors, mechanisms, and consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Detection of mammalian virulence determinants in highly pathogenic avian influenza H5N1 viruses: multivariate analysis of published data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Pathogenicity of highly pathogenic avian influenza virus in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Cell polarity proteins: common targets for tumorigenic human viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Analysis of influenza B Virus NS1 protein trafficking reveals a novel interaction with nuclear speckle domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

SMART 6: recent updates and new developments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

A specificity map for the PDZ domain family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Analysis of cytokine secretion from human plasmacytoid dendritic cells infected with H5N1 or low-pathogenicity influenza viruses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

The multifunctional NS1 protein of influenza A viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Distinctly different expression of cytokines and chemokines in the lungs of two H5N1 avian influenza patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Role of hypercytokinemia in NF-kappaB p50-deficient mice after H5N1 influenza A virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Clinical characteristics of 26 human cases of highly pathogenic avian influenza A (H5N1) virus infection in China

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Sabotage of antiviral signaling and effectors by influenza viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Review of clinical symptoms and spectrum in humans with influenza A/H5N1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Update on avian influenza A (H5N1) virus infection in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

The influenza virus resource at the National Center for Biotechnology Information

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Inhibition of the cytokine response does not protect against lethal H5N1 influenza infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Molecular changes in the polymerase genes (PA and PB1) associated with high pathogenicity of H5N1 influenza virus in mallard ducks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Nuclear and nucleolar targeting of influenza A virus NS1 protein: striking differences between different virus subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Rapid and highly sensitive pathotyping of avian influenza A H5N1 virus by using real-time reverse transcription-PCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

The NS1 gene contributes to the virulence of H5N1 avian influenza viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Global patterns of influenza a virus in wild birds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Molecular biology of human papillomavirus infection and cervical cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Large-scale sequence analysis of avian influenza isolates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Identification of a bacterial type III effector family with G protein mimicry functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

PDZ binding motif of HTLV-1 Tax promotes virus-mediated T-cell proliferation in vitro and persistence in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Virulence may determine the necessary duration and dosage of oseltamivir treatment for highly pathogenic A/Vietnam/1203/04 influenza virus in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

PDZ domain proteins of synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Avian influenza A (H5N1) in 10 patients in Vietnam

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

The influenza B virus nonstructural NS1 protein is essential for efficient viral growth and antagonizes beta interferon induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Lethal H5N1 influenza viruses escape host anti-viral cytokine responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

PDZ domains: structural modules for protein complex assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Mechanism and role of PDZ domains in signaling complex assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

5 July 2018

Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses

1 reference

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5 July 2018

Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication.

1 reference

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5 July 2018

A DNA transfection system for generation of influenza A virus from eight plasmids

1 reference

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5 July 2018

Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells

1 reference

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5 July 2018

Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

1 reference

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5 July 2018

Influenza virus NS1 protein interacts with viral transcription-replication complexes in vivo

1 reference

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5 July 2018

A single amino acid in the PB2 gene of influenza A virus is a determinant of host range.

1 reference

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5 July 2018

Proprotein-processing endoproteases PC6 and furin both activate hemagglutinin of virulent avian influenza viruses.

1 reference

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5 July 2018

Influenza viruses, cell enzymes, and pathogenicity

1 reference

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5 July 2018

Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice

1 reference

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28 October 2018

PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexes

1 reference

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28 October 2018

Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950580

28 October 2018

Virology. Clues to the virulence of H5N1 viruses in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/20686040

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

H5N1 infection of the respiratory tract and beyond: a molecular pathology study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20686040

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00610-10

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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