(Q34186659)

31 July 2017

title

PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein (English)

1 reference

31 July 2017

1 reference

C G Li

1

1 reference

31 July 2017

J E Nyman

series ordinal

2

1 reference

31 July 2017

A W Braithwaite

series ordinal

3

1 reference

31 July 2017

M R Eccles

series ordinal

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

23 May 2011

1 reference

31 July 2017

1 reference

31 July 2017

volume

30

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31 July 2017

issue

48

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31 July 2017

page(s)

4824-4834

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Loss of pRB causes centromere dysfunction and chromosomal instability

31 July 2017

cites work

1 reference

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Lysine methylation regulates the pRb tumour suppressor protein

5 July 2018

1 reference

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Is there such a thing as a renal stem cell?

5 July 2018

1 reference

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Cellular mechanisms of tumour suppression by the retinoblastoma gene.

5 July 2018

1 reference

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PAX8 regulates telomerase reverse transcriptase and telomerase RNA component in glioma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

A rapid micro chromatin immunoprecipitation assay (microChIP).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

ConTra: a promoter alignment analysis tool for identification of transcription factor binding sites across species

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

DNA-damage response control of E2F7 and E2F8

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Mechanisms controlling cell cycle exit upon terminal differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Successful co-immunoprecipitation of Oct4 and Nanog using cross-linking

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Regulation of cell lineage specification by the retinoblastoma tumor suppressor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Stabilization of the retinoblastoma protein by A-type nuclear lamins is required for INK4A-mediated cell cycle arrest

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

PAX2 inactivation enhances cisplatin-induced apoptosis in renal carcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Differential gene expression in ovarian carcinoma: identification of potential biomarkers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Molecular mechanisms of E2F-dependent activation and pRB-mediated repression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Genomic targets of the human c-Myc protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Proteasome-dependent, ubiquitin-independent degradation of the Rb family of tumor suppressors by the human cytomegalovirus pp71 protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Nephric lineage specification by Pax2 and Pax8

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Pax-2 expression in adult renal tumors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Autosomal dominant transmission of congenital thyroid hypoplasia due to loss-of-function mutation of PAX8

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Human thyroid cancer cells as a source of iso-genic, iso-phenotypic cell lines with or without functional p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Pax-8 protein levels regulate thyroglobulin gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

The regulation of E2F by pRB-family proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Follicular cells of the thyroid gland require Pax8 gene function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

PAX 8 activates the enhancer of the human thyroperoxidase gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

The human papillomavirus E7 oncoprotein functionally interacts with the S4 subunit of the 26 S proteasome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Pax genes and organogenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Concentration of RB protein in nucleus vs. cytoplasm is stable as phosphorylation of RB changes during the cell cycle and differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Distinct functional properties of three human paired-box-protein, PAX8, isoforms generated by alternative splicing in thyroid, kidney and Wilms' tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

The retinoblastoma protein and cell cycle control

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Function of the homeo and paired domain proteins TTF-1 and Pax-8 in thyroid cell proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

The E2F transcription factor is a cellular target for the RB protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

Emerging roles for PAX8 in ovarian cancer and endosalpingeal development.

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

A role for Myc in facilitating transcription activation by E2F1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Stem cell therapies benefit Alport syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Primary extragastrointestinal stromal tumor of the pleura: report of a unique case with genetic confirmation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Retinoblastoma protein acts as Pax 8 transcriptional coactivator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Escape from premature senescence is not sufficient for oncogenic transformation by Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Disruption of base-paired U4.U6 small nuclear RNAs induced by mammalian heterogeneous nuclear ribonucleoprotein C protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Roles of Pax-genes in developing and adult brain as suggested by expression patterns.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229668

PAX2: a reliable marker for nephrogenic adenoma

28 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

PAX3 Is extensively expressed in benign and malignant tissues of the melanocytic lineage in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Expression of PAX8 in normal and neoplastic renal tissues: an immunohistochemical study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Immunohistochemical analysis of thyroid-specific transcription factors in thyroid tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.190

Acetylation control of the retinoblastoma tumour-suppressor protein

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21602887

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PAX8 Expression in Well-differentiated Pancreatic Endocrine Tumors: Correlation With Clinicopathologic Features and Comparison With Gastrointestinal and Pulmonary Carcinoid Tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21602887

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2011.190

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference