(Q34187378)

31 July 2017

title

Simulations of human lysozyme: probing the conformations triggering amyloidosis (English)

1 reference

31 July 2017

George Moraitakis

1

1 reference

31 July 2017

Julia M Goodfellow

series ordinal

2

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 April 2003

1 reference

31 July 2017

1 reference

31 July 2017

volume

84

1 reference

31 July 2017

issue

4

1 reference

31 July 2017

page(s)

2149-2158

1 reference

Long timescale simulations

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Staphylococcal protein A: unfolding pathways, unfolded states, and differences between the B and E domains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Mechanistic studies of the folding of human lysozyme and the origin of amyloidogenic behavior in its disease-related variants.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Tertiary structures of amyloidogenic and non-amyloidogenic transthyretin variants: new model for amyloid fibril formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Human lysozyme gene mutations cause hereditary systemic amyloidosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Detection of transient protein folding populations by mass spectrometry

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Characterization of the transition state of protein unfolding by use of molecular dynamics: chymotrypsin inhibitor 2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Theoretical studies of protein folding and unfolding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Refinement of human lysozyme at 1.5 Å resolution analysis of non-bonded and hydrogen-bond interactions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Mechanism of lysozyme action

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Demonstration by NMR of folding domains in lysozyme

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Dynamic Monte Carlo simulations of a new lattice model of globular protein folding, structure and dynamics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. II. Plastocyanin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Local interactions in bends of proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Unfolding of hen egg lysozyme by molecular dynamics simulations at 300K: insight into the role of the interdomain interface.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Amyloid fibril formation and seeding by wild-type human lysozyme and its disease-related mutational variants.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Analysis methods for comparison of multiple molecular dynamics trajectories: applications to protein unfolding pathways and denatured ensembles

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Non-native interactions in protein folding intermediates: molecular dynamics simulations of hen lysozyme

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Simulations of protein folding and unfolding

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Molecular dynamics simulation of the unfolding of barnase: characterization of the major intermediate

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Modelling protein unfolding: hen egg-white lysozyme

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Computational approaches to study protein unfolding: hen egg white lysozyme as a case study

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Local cooperativity in the unfolding of an amyloidogenic variant of human lysozyme

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302782

Molecular dynamics with coupling to an external bath

28 October 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2975021-8

GROMACS: A message-passing parallel molecular dynamics implementation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2975021-8

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2975021-8

Folding of peptide fragments comprising the complete sequence of proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2975021-8

Simulation of the thermal denaturation of hen egg white lysozyme: trapping the molten globule state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2975021-8

Reverse turns in blocked dipeptides are intrinsically unstable in water

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2975021-8

Free energy determinants of secondary structure formation: III. beta-turns and their role in protein folding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2975021-8

10.1016/S0006-3495(03)75021-8

7 January 2021

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference