(Q34194189)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

Rafael P Vázquez-Manrique

25 January 2020

main subject

Caenorhabditis elegans

0 references

author

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Alex J Parker

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Jean-Philippe Vert

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Christian Neri

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

François-Xavier Lejeune

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Lilia Mesrob

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Frédéric Parmentier

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Cedric Bicep

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Cendrine Tourette

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

language of work or name

English

0 references

publication date

13 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

91

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

A genetic screening strategy identifies novel regulators of the proteostasis network

25 January 2020

cites work

1 reference

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Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.

28 July 2018

1 reference

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Not(ch) just development: Notch signalling in the adult brain

28 July 2018

1 reference

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Novel histopathologic findings in molecularly-confirmed pantothenate kinase-associated neurodegeneration

28 July 2018

1 reference

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The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Molecular mechanisms and potential therapeutical targets in Huntington's disease

28 July 2018

1 reference

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Enhanced neuronal RNAi in C. elegans using SID-1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

RNAi screening in Drosophila cells identifies new modifiers of mutant huntingtin aggregation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Neurosensory mechanotransduction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Implication of the JNK pathway in a rat model of Huntington's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Mechanisms of neurodegeneration in Huntington's disease.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Ontologizer 2.0--a multifunctional tool for GO term enrichment analysis and data exploration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Huntingtin interacting proteins are genetic modifiers of neurodegeneration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Classification of microarray data using gene networks

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Regional and cellular gene expression changes in human Huntington's disease brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

The druggable genome: an update

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Towards a proteome-scale map of the human protein–protein interaction network

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

A human protein-protein interaction network: a resource for annotating the proteome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Synaptic dysfunction in Huntington's disease: a new perspective.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

WormBase: a comprehensive data resource for Caenorhabditis biology and genomics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

A map of the interactome network of the metazoan C. elegans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

A protein interaction map of Drosophila melanogaster

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Innate immunity: the missing link in neuroprotection and neurodegeneration?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Automatic clustering of orthologs and in-paralogs from pairwise species comparisons

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Genes regulating touch cell development in Caenorhabditis elegans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Neurological abnormalities in a knock-in mouse model of Huntington's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Gene ontology: tool for the unification of biology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

KEGG: kyoto encyclopedia of genes and genomes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

The genetics of Caenorhabditis elegans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

28 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-13-91

Polyglutamine repeat length-dependent proteolysis of huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-13-91

Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-13-91

C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-13-91

A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-13-91

An improved, bias-reduced probabilistic functional gene network of baker's yeast, Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-13-91

A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-13-91

Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-13-91

Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-13-91

Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-13-91

VisANT 3.5: multi-scale network visualization, analysis and inference based on the gene ontology.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3331833

28 October 2018

Identifiers

DOI

10.1186/1471-2164-13-91

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22413862%20AND%20SRC:MED&resulttype=core&format=json