(Q34195780)

31 July 2017

title

An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele (English)

1 reference

31 July 2017

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7597093

4 June 2024

2

J. G. Pichel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7597093

4 June 2024

author name string

T. Nakamura

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7597093

4 June 2024

L. Williams-Simons

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7597093

4 June 2024

H. Westphal

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7597093

4 June 2024

language of work or name

English

0 references

publication date

1 June 1995

1 reference

31 July 2017

20 June 1995

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7597093

4 June 2024

number of pages

5

1 reference

full work available at URL

inferred from page(s)

http://www.pnas.org/content/pnas/92/13/6142.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7597093

https://europepmc.org/articles/PMC41658

4 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7597093

https://europepmc.org/articles/PMC41658?pdf=render

4 June 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7597093

https://pnas.org/doi/pdf/10.1073/pnas.92.13.6142

4 June 2024

1 reference

Crossref

DOI

10.1073/PNAS.92.13.6142

https://api.crossref.org/works/10.1073/PNAS.92.13.6142

Proceedings of the National Academy of Sciences of the United States of America

4 June 2024

published in

1 reference

31 July 2017

volume

92

1 reference

31 July 2017

issue

13

1 reference

31 July 2017

page(s)

6142-6146

1 reference

p53 is required for radiation-induced apoptosis in mouse thymocytes

31 July 2017

cites work

1 reference

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mdm2 expression is induced by wild type p53 activity

5 July 2018

1 reference

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The p53-mdm-2 autoregulatory feedback loop

5 July 2018

1 reference

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p21 is a universal inhibitor of cyclin kinases

5 July 2018

1 reference

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WAF1, a potential mediator of p53 tumor suppression

5 July 2018

1 reference

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

5 July 2018

1 reference

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5 July 2018

1 reference

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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

5 July 2018

1 reference

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p53 induction is associated with neuronal damage in the central nervous system

5 July 2018

1 reference

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p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

5 July 2018

1 reference

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

5 July 2018

1 reference

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Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

5 July 2018

1 reference

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Lens differentiation in vertebrates. A review of cellular and molecular features

5 July 2018

1 reference

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Denucleation process of the lens.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41658

Lens-specific expression of the chloramphenicol acetyltransferase gene promoted by 5' flanking sequences of the murine alpha A-crystallin gene in explanted chicken lens epithelia

5 July 2018

1 reference

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Oncogenesis of the lens in transgenic mice.

5 July 2018

1 reference

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Molecular basis for heterogeneity of the human p53 protein

5 July 2018

1 reference

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Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41658

Overexpression of the vimentin gene in transgenic mice inhibits normal lens cell differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41658

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

5 July 2018

1 reference

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Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation

5 July 2018

1 reference

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Differentiation and oncogenesis: phenotypically distinct lens tumors in transgenic mice

5 July 2018

1 reference

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High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

5 July 2018

1 reference

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Functional inactivation of genes by dominant negative mutations

5 July 2018

1 reference

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Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

5 July 2018

1 reference

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Suppression of human colorectal carcinoma cell growth by wild-type p53

5 July 2018

1 reference

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Identification of p53 as a sequence-specific DNA-binding protein

5 July 2018

1 reference

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The p53 tumour suppressor gene

5 July 2018

1 reference

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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

5 July 2018

1 reference

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Oncogenic forms of p53 inhibit p53-regulated gene expression

5 July 2018

1 reference

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Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

5 July 2018

1 reference

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

5 July 2018

1 reference

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Gene therapy of cancer through restoration of tumor-suppressor functions?

5 July 2018

1 reference

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p53 function and dysfunction

5 July 2018

1 reference

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Wild-type p53 binds to the TATA-binding protein and represses transcription

5 July 2018

1 reference

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

5 July 2018

1 reference

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

5 July 2018

1 reference

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41658

Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41658

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

28 October 2018

1 reference

12 December 2020

Nuclear breakdown during terminal differentiation of primary lens fibres in mice: a transmission electron microscopic study

1 reference

12 December 2020

Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development

1 reference

12 December 2020

p53 status and the efficacy of cancer therapy in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.92.13.6142

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference