(Q34197279)

31 July 2017

title

Imprint of somatic hypermutation differs in human immunoglobulin heavy and lambda chain variable gene segments (English)

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31 July 2017

Jo Spencer

3

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ORCID Public Data File 2021

author name string

Laurent Boursier

series ordinal

1

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31 July 2017

Wen Su

series ordinal

2

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31 July 2017

publication date

1 June 2003

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31 July 2017

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31 July 2017

volume

39

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31 July 2017

issue

16

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31 July 2017

page(s)

1025-1034

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5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro

31 July 2017

cites work

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7 January 2021

Maturation of the immune response in germinal centers

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7 January 2021

Sequence analysis of light chain genes from human intestinal plasma cells demonstrates that lambda genes are almost all in-frame and highly mutated and most kappa genes are highly mutatedwhen in-frame and minimally mutated when out-of-frame

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2803%2900033-6

7 January 2021

Enhanced evolvability in immunoglobulin V genes under somatic hypermutation

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7 January 2021

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

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7 January 2021

Hypermutation, diversity and dissemination of human intestinal lamina propria plasma cells

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7 January 2021

Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

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7 January 2021

Immunology: the roots of antibody diversity

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7 January 2021

Codon bias and plasticity in immunoglobulins

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https://api.crossref.org/works/10.1016%2FS0161-5890%2803%2900033-6

7 January 2021

Hypermutation in shark immunoglobulin light chain genes results in contiguous substitutions

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https://api.crossref.org/works/10.1016%2FS0161-5890%2803%2900033-6

7 January 2021

Both DNA strands of antibody genes are hypermutation targets

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7 January 2021

Targeting and selection of mutations in human Vlambda rearrangements

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7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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7 January 2021

Genetic plasticity of V genes under somatic hypermutation: statistical analyses using a new resampling-based methodology

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7 January 2021

Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene.

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7 January 2021

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

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7 January 2021

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

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7 January 2021

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

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7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

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7 January 2021

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

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7 January 2021

Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.

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7 January 2021

Evolution of Ig DNA sequence to target specific base positions within codons for somatic hypermutation

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7 January 2021

Codon bias targets mutation.

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7 January 2021

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2803%2900033-6

7 January 2021

Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2803%2900033-6

7 January 2021

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2803%2900033-6

7 January 2021

DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2803%2900033-6

7 January 2021

10.1016/S0161-5890(03)00033-6

Identifiers

DOI

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31 July 2017

1 reference