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Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration.
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Europe PubMed Central
PMCID
2955804
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
title
Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2955804
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
main subject
breast cancer
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inferred from title
author
Jessica L Fry
series ordinal
1
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Europe PubMed Central
PMCID
2955804
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
author name string
Alex Toker
series ordinal
2
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stated in
Europe PubMed Central
PMCID
2955804
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
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11 February 2020
language of work or name
English
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publication date
24 August 2010
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stated in
Europe PubMed Central
PMCID
2955804
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
published in
Cancer Research
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stated in
Europe PubMed Central
PMCID
2955804
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
volume
70
1 reference
stated in
Europe PubMed Central
PMCID
2955804
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
page(s)
8187-8198
1 reference
stated in
Europe PubMed Central
PMCID
2955804
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
issue
20
1 reference
stated in
Europe PubMed Central
PMCID
2955804
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
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Inhibition of platelets and tumor cell adhesion by the disintegrin domain of human ADAM9 to collagen I under dynamic flow conditions.
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PubMed Central
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28 July 2018
ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase
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PubMed Central
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28 July 2018
A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10.
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PubMed Central
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28 July 2018
Identification of genes that regulate epithelial cell migration using an siRNA screening approach
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PubMed Central
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28 July 2018
Role of ADAM-9 disintegrin-cysteine-rich domains in human keratinocyte migration
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PubMed Central
reference URL
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28 July 2018
Reactive oxygen species mediate androgen receptor- and serum starvation-elicited downstream signaling of ADAM9 expression in human prostate cancer cells
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PubMed Central
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28 July 2018
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
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28 July 2018
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
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28 July 2018
Oxidative stress induces ADAM9 protein expression in human prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
ADAM-9 (MDC-9/meltrin-gamma), a member of the a disintegrin and metalloproteinase family, regulates myeloma-cell-induced interleukin-6 production in osteoblasts by direct interaction with the alpha(v)beta5 integrin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
Overexpression of ADAM9 enhances growth factor-mediated recycling of E-cadherin in human colon cancer cell line HT29 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
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28 July 2018
Adam-9 expression and regulation in human skin melanoma and melanoma cell lines
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
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28 July 2018
Tumor-stroma interactions: their role in the control of tumor cell invasion.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
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28 July 2018
ADAM15 decreases integrin alphavbeta3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
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28 July 2018
Increased expression of ADAM family members in human breast cancer and breast cancer cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
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28 July 2018
HB-EGF is a potent inducer of tumor growth and angiogenesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
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28 July 2018
Evidence of antiangiogenic and antimetastatic activities of the recombinant disintegrin domain of metargidin
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
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28 July 2018
Role of tissue stroma in cancer cell invasion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
Expression of ADAM-9 mRNA and protein in human breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
The ADAMs family of metalloproteases: multidomain proteins with multiple functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
Meltrin gamma(ADAM-9) mediates cellular adhesion through alpha(6)beta(1 )integrin, leading to a marked induction of fibroblast cell motility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
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28 July 2018
SUM-159PT cells: a novel estrogen independent human breast cancer model system
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
Matrix metalloproteinases as insulin-like growth factor binding protein-degrading proteinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
The integrin alpha 6 beta 4 is a laminin receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 July 2018
The ADAMs: signalling scissors in the tumour microenvironment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
Urinary metalloproteinases: noninvasive biomarkers for breast cancer risk assessment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
ADAM15 gene structure and differential alternative exon use in human tissues.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
Proteolytic processing of delta-like 1 by ADAM proteases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
How ADAM-9 and ADAM-11 differentially from estrogen receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: a retrospective study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
A role for ADAM12 in breast tumor progression and stromal cell apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
Tumor cell invasiveness correlates with changes in integrin expression and localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
ADAM13 disintegrin and cysteine-rich domains bind to the second heparin-binding domain of fibronectin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804
retrieved
28 October 2018
Critical function for ADAM9 in mouse prostate cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20736367
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Early response cytokines and innate immunity: essential roles for TNF receptor 1 and type I IL-1 receptor during Escherichia coli pneumonia in mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20736367
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/0008-5472.CAN-09-4231
1 reference
stated in
Europe PubMed Central
PMCID
2955804
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
PMCID
2955804
1 reference
stated in
Europe PubMed Central
PMCID
2955804
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
PubMed ID
20736367
1 reference
stated in
Europe PubMed Central
PMCID
2955804
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
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