(Q34207648)

31 July 2017

title

Distinct Methylation of IFNG in the Gut (English)

1 reference

31 July 2017

3

Stephan R Targan

1 reference

31 July 2017

Rivkah Gonsky

1

1 reference

31 July 2017

Richard L Deem

series ordinal

2

1 reference

31 July 2017

publication date

1 July 2009

1 reference

Journal of Interferon and Cytokine Research

31 July 2017

published in

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31 July 2017

volume

29

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31 July 2017

issue

7

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31 July 2017

page(s)

407-414

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Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma

31 July 2017

cites work

1 reference

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Inhibition of IFN-gamma transcription by site-specific methylation during T helper cell development

28 July 2018

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Mucosa-specific targets for regulation of IFN-gamma expression: lamina propria T cells use different cis-elements than peripheral blood T cells to regulate transactivation of IFN-gamma expression

28 July 2018

1 reference

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Animal models of mucosal inflammation and their relation to human inflammatory bowel disease

28 July 2018

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Local and systemic liberation of proinflammatory cytokines in ulcerative colitis

28 July 2018

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Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production

28 July 2018

1 reference

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Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells

28 July 2018

1 reference

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Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

28 July 2018

1 reference

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Cytokines in intestinal inflammation: pathophysiological and clinical considerations.

28 July 2018

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Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene

28 July 2018

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Undermethylation of interferon-gamma gene in human T cell lines and normal T lymphocytes

28 July 2018

1 reference

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Interferon-gamma gene expression in human B-cell lines: induction by interleukin-2, protein kinase C activators, and possible effect of hypomethylation on gene regulation

28 July 2018

1 reference

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IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

28 July 2018

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Dynamic changes in histone-methylation 'marks' across the locus encoding interferon-gamma during the differentiation of T helper type 2 cells.

28 October 2018

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A distal conserved sequence element controls Ifng gene expression by T cells and NK cells.

28 October 2018

1 reference

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28 October 2018

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Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease

28 October 2018

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A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956574

Cutting Edge: Innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter.

28 October 2018

1 reference

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Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene.

28 October 2018

1 reference

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Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO- T cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956574

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956574

Cutting edge: stable epigenetic inheritance of regional IFN-gamma promoter demethylation in CD44highCD8+ T lymphocytes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956574

Human mucosal cytotoxic effector cells

28 October 2018

1 reference

12 December 2020

Interferon gamma production by human intestinal mucosal mononuclear cells. Decreased levels in inflammatory bowel disease

1 reference

12 December 2020

Interleukin 4 in inflammatory bowel disease and mucosal immune reactivity

1 reference

12 December 2020

The pathogenesis of mucosal inflammation in murine models of inflammatory bowel disease and Crohn disease

1 reference

12 December 2020

Hypomethylation of the proximal and intronic regulatory regions of the IFN-Î³ gene is not essential for its transcription by naive CD4+ T cells cultured with IL-4

1 reference

12 December 2020

Identifiers

DOI

10.1089/JIR.2008.0109

1 reference

31 July 2017

1 reference

31 July 2017

1 reference