(Q34220190)

31 July 2017

title

Methodologies for the isolation of alternative binders with improved clinical potentiality over conventional antibodies (English)

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31 July 2017

Ario de Marco

1

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31 July 2017

publication date

4 April 2012

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Critical Reviews in Biotechnology

31 July 2017

published in

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31 July 2017

volume

33

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31 July 2017

issue

1

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31 July 2017

page(s)

40-48

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Fine tuning of receptor-selectivity for tumor necrosis factor-α using a phage display system with one-step competitive panning.

31 July 2017

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The availability of a recombinant anti-SNAP antibody in VHH format amplifies the application flexibility of SNAP-tagged proteins

21 January 2018

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Monoclonal antibodies - a proven and rapidly expanding therapeutic modality for human diseases

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Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy

21 January 2018

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Partial analysis of the flagellar antigenic determinant recognized by a monoclonal antibody to Clostridium tyrobutyricum

21 January 2018

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Identification of a murine ICAM-1-specific peptide by subtractive phage library selection on cells

21 January 2018

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Persistent elimination of ErbB-2/HER2-overexpressing tumors using combinations of monoclonal antibodies: relevance of receptor endocytosis

21 January 2018

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High-affinity binders selected from designed ankyrin repeat protein libraries

21 January 2018

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Bispecific designed ankyrin repeat proteins (DARPins) targeting epidermal growth factor receptor inhibit A431 cell proliferation and receptor recycling

21 January 2018

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Bi-specific aptamers mediating tumor cell lysis

21 January 2018

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Polyclonal antibodies elicited against trans-diamminedichloroplatinum(II)-modified DNA and their application in nonradioactive hybridization experiments

21 January 2018

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Beyond natural antibodies: the power of in vitro display technologies

21 January 2018

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Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

21 January 2018

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Isolating and engineering human antibodies using yeast surface display

21 January 2018

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Isolation of llama antibody fragments for prevention of dandruff by phage display in shampoo

21 January 2018

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Single domain antibodies are specially suited for quantitative determination of gliadins under denaturing conditions

21 January 2018

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DARPins as bispecific receptor antagonists analyzed for immunoglobulin E receptor blockage.

21 January 2018

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Inhibition of ongoing allergic reactions using a novel anti-IgE DARPin-Fc fusion protein.

21 January 2018

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Llama antibody fragments with cross-subtype human immunodeficiency virus type 1 (HIV-1)-neutralizing properties and high affinity for HIV-1 gp120

21 January 2018

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Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

21 January 2018

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Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy

21 January 2018

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An efficient chemical approach to bispecific antibodies and antibodies of high valency

21 January 2018

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Function-modulating human monoclonal antibodies against platelet-membrane receptors isolated from a phage-display library

21 January 2018

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VHH, bivalent domains and chimeric Heavy chain-only antibodies with high neutralizing efficacy for scorpion toxin AahI'.

21 January 2018

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ERBB receptors and cancer: the complexity of targeted inhibitors

21 January 2018

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Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425

21 January 2018

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Targeting adenoviral vectors by using the extracellular domain of the coxsackie-adenovirus receptor: improved potency via trimerization

21 January 2018

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Dimeric and trimeric antibodies: high avidity scFvs for cancer targeting.

21 January 2018

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https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Development of a two-part strategy to identify a therapeutic human bispecific antibody that inhibits IgE receptor signaling

21 January 2018

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CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells

21 January 2018

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Recombinant antibodies: engineering and production in yeast and bacterial hosts

21 January 2018

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https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Augmentation of antitumor effects of p53 gene therapy by combination with HDAC inhibitor

21 January 2018

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https://api.crossref.org/works/10.3109%2F07388551.2012.665353

In vivo therapeutic synergism of anti-epidermal growth factor receptor and anti-HER2 monoclonal antibodies against pancreatic carcinomas

21 January 2018

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https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Heavy chain-only antibodies and tetravalent bispecific antibody neutralizing Staphylococcus aureus leukotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8

21 January 2018

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Biotechnological applications of recombinant single-domain antibody fragments

21 January 2018

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https://api.crossref.org/works/10.3109%2F07388551.2012.665353

A simple vector system to improve performance and utilisation of recombinant antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Selection of phage-displayed antibodies specific for a cytoskeletal antigen by competitive elution with a monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Immunological applications of single-domain llama recombinant antibodies isolated from a naïve library

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Identification of amino acids involved in the Flo11p-mediated adhesion of Saccharomyces cerevisiae to a polystyrene surface using phage display with competitive elution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

A multi-Fc-species system for recombinant antibody production

21 January 2018

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https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Therapeutic assessment of SEED: a new engineered antibody platform designed to generate mono- and bispecific antibodies

21 January 2018

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VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

21 January 2018

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Heating as a rapid purification method for recovering correctly-folded thermotolerant VH and VHH domains

21 January 2018

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https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Sym004: a novel synergistic anti-epidermal growth factor receptor antibody mixture with superior anticancer efficacy.

21 January 2018

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https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human anti-human VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Transglutaminase-catalyzed covalent multimerization of Camelidae anti-human TNF single domain antibodies improves neutralizing activity.

21 January 2018

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https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Efficient inhibition of EGFR signaling and of tumour growth by antagonistic anti-EFGR Nanobodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

DARPins recognizing the tumor-associated antigen EpCAM selected by phage and ribosome display and engineered for multivalency

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Isolation, characterization and pentamerization of alpha-cobrotoxin specific single-domain antibodies from a naïve phage display library: preliminary findings for antivenom development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

The assembly of single domain antibodies into bispecific decavalent molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

A novel pentamer versus pentamer approach to generating neutralizers of verotoxin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Single-domain antibodies that compete with the natural ligand fibroblast growth factor block the internalization of the fibroblast growth factor receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

A DNA-binding peptide from a phage display library

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Pentamerization of single-domain antibodies from phage libraries: a novel strategy for the rapid generation of high-avidity antibody reagents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

A bispecific nanobody to provide full protection against lethal scorpion envenoming

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07388551.2012.665353

10.3109/07388551.2012.665353

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference