(Q33966937)

30 July 2017

title

Development of a two-part strategy to identify a therapeutic human bispecific antibody that inhibits IgE receptor signaling (English)

1 reference

30 July 2017

16

Merone Roose-Girma

1 reference

30 July 2017

Janet Jackman

1

1 reference

30 July 2017

Yongmei Chen

2

1 reference

30 July 2017

Arthur Huang

3

1 reference

30 July 2017

Barbara Moffat

4

1 reference

30 July 2017

Justin M Scheer

5

1 reference

30 July 2017

Steven R Leong

6

1 reference

30 July 2017

Wyne P Lee

7

1 reference

30 July 2017

Juan Zhang

8

1 reference

30 July 2017

Navneet Sharma

9

1 reference

30 July 2017

Yanmei Lu

10

1 reference

30 July 2017

Suhasini Iyer

11

1 reference

30 July 2017

Robert L Shields

12

1 reference

30 July 2017

Nancy Chiang

13

1 reference

30 July 2017

Michele C Bauer

14

1 reference

30 July 2017

Diana Wadley

15

1 reference

30 July 2017

Richard Vandlen

17

1 reference

30 July 2017

Daniel G Yansura

18

1 reference

30 July 2017

Yan Wu

19

1 reference

30 July 2017

Lawren C Wu

20

1 reference

30 July 2017

language of work or name

English

0 references

publication date

5 May 2010

1 reference

Journal of Biological Chemistry

30 July 2017

published in

1 reference

30 July 2017

volume

285

1 reference

30 July 2017

issue

27

1 reference

30 July 2017

page(s)

20850-20859

1 reference

Aglycosylated IgG variants expressed in bacteria that selectively bind FcgammaRI potentiate tumor cell killing by monocyte-dendritic cells

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

BiTE: Teaching antibodies to engage T-cells for cancer therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Tumor regression in cancer patients by very low doses of a T cell-engaging antibody

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

"Accentuate the negative, eliminate the positive": engineering allergy therapeutics to block allergic reactivity through negative signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Highly effective recombinant format of a humanized IgG-like bispecific antibody for cancer immunotherapy with retargeting of lymphocytes to tumor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Anti-IgE antibodies for the treatment of IgE-mediated allergic diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Function blocking antibodies to neuropilin-1 generated from a designed human synthetic antibody phage library

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Engineered antibody fragments and the rise of single domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Recombinant approaches to IgG-like bispecific antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Fc receptor targeting in the treatment of allergy, autoimmune diseases and cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Targeting the IgE molecule in allergic and asthmatic diseases: review of the IgE molecule and clinical efficacy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Omalizumab-induced reductions in mast cell Fce psilon RI expression and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

A revival of bispecific antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Inhibitory receptors and allergy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

A novel human immunoglobulin Fc gamma Fc epsilon bifunctional fusion protein inhibits Fc epsilon RI-mediated degranulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Bispecific and bifunctional single chain recombinant antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Bispecific human IgG by design

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Immune inhibitory receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Immunotherapeutic perspective for bispecific antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

The inhibitory receptor superfamily: potential relevance to atopy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Regulation of immune responses through inhibitory receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

An efficient route to human bispecific IgG.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Stable heterodimers from remodeling the domain interface of a homodimer using a phage display library

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Aglycosylation of human IgG1 and IgG3 monoclonal antibodies can eliminate recognition by human cells expressing Fc gamma RI and/or Fc gamma RII receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Studies of aglycosylated chimeric mouse-human IgG. Role of carbohydrate in the structure and effector functions mediated by the human IgG constant region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Humanization of an anti-p185HER2 antibody for human cancer therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898330

Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113910

The same tyrosine-based inhibition motif, in the intra-cytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113910

A bispecific antibody against human IgE and human FcgammaRII that inhibits antigen-induced histamine release by human mast cells and basophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113910

A chimeric human-cat fusion protein blocks cat-induced allergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113910

Expression of full-length immunoglobulins in Escherichia coli: rapid and efficient production of aglycosylated antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113910

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113910

Negative regulation of FcϵRI signaling by FcγRII costimulation in human blood basophils

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20444694

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PHASE I STUDY OF AN ENGINEERED AGLYCOSYLATED HUMANIZED CD3 ANTIBODY IN RENAL TRANSPLANT REJECTION1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20444694

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High affinity human IgE receptor (Fc epsilon RI). Analysis of functional domains of the alpha-subunit with monoclonal antibodies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20444694

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.113910

1 reference

30 July 2017

1 reference

30 July 2017

1 reference