(Q36066311)

12 August 2017

1 reference

title

Fc receptor targeting in the treatment of allergy, autoimmune diseases and cancer. (English)

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12 August 2017

Akira Nakamura

1

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12 August 2017

Kenichi Akiyama

series ordinal

2

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12 August 2017

Toshiyuki Takai

series ordinal

3

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12 August 2017

language of work or name

English

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publication date

1 February 2005

1 reference

Expert Opinion on Therapeutic Targets

12 August 2017

published in

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12 August 2017

volume

9

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12 August 2017

issue

1

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12 August 2017

page(s)

169-190

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New concepts about the mast cell

12 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

The high-affinity IgE receptor (Fc epsilon RI): from physiology to pathology

21 January 2018

1 reference

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The central role of FcepsilonRI in allergy

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Effector lymphocytes in autoimmunity

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Regulation of antibody responses via antibodies, complement, and Fc receptors

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Fc receptors are major mediators of antibody based inflammation in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Variations in immune response genes and their associations with multifactorial immune disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

FcgammaRIIIA-158V and rheumatoid arthritis: a confirmation study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc epsilonRI alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

The structure of a human type III Fcgamma receptor in complex with Fc

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Human antibody-Fc receptor interactions illuminated by crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Crystal structure of the human leukocyte Fc receptor, Fc gammaRIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Crystal structure of the human high-affinity IgE receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Crystal structure of the ectodomain of human FcalphaRI

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

SHIP modulates immune receptor responses by regulating membrane association of Btk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Regulation of mast-cell and basophil function and survival by IgE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Transphosphorylation as the mechanism by which the high-affinity receptor for IgE is phosphorylated upon aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Role of phosphoinositide 3-kinase signaling in mast cells: new insights from knockout mouse studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

FcepsilonRI signaling observed from the inside of the mast cell membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Phagocytic signaling strategies: Fc(gamma)receptor-mediated phagocytosis as a model system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Protein kinase C-alpha participates in FcgammaR-mediated phagocytosis in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Fcgamma receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Function of Rho family proteins in actin dynamics during phagocytosis and engulfment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Implicating a role for immune recognition of self in tumor rejection: passive immunization against the brown locus protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Fc receptors are required in passive and active immunity to melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Antitumor monoclonal antibodies enhance cross-presentation ofcCellular antigens and the generation of myeloma-specific killer T cells by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Identification of the transferrin receptor as a novel immunoglobulin (Ig)A1 receptor and its enhanced expression on mesangial cells in IgA nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

IgG transcytosis and recycling by FcRn expressed in MDCK cells reveals ligand-induced redistribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

A second amplifier function for the allergy-associated Fc(epsilon)RI-beta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Competing Functions Encoded in the Allergy-Associated FcϵRIβ Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Activating and inhibitory nature of the murine paired immunoglobulin-like receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor alpha chain gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by low-affinity Fc receptors for IgG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Negative feedback regulation of IgE synthesis by murine CD23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Autoreactivity by design: innate B and T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Induction and suppression of collagen-induced arthritis is dependent on distinct fcgamma receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Resistance of Fc receptor- deficient mice to fatal glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Arthritis critically dependent on innate immune system players

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Arthritogenic monoclonal antibodies from K/BxN mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Expression of FcgammaRIII is required for development of collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Modulation of immune complex-induced inflammation in vivo by the coordinate expression of activation and inhibitory Fc receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Fcgamma receptor IIB-deficient mice develop Goodpasture's syndrome upon immunization with type IV collagen: a novel murine model for autoimmune glomerular basement membrane disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Autoimmunity to type II collagen an experimental model of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Deletion of fcgamma receptor IIB renders H-2(b) mice susceptible to collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Delineating the genetic basis of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Fc-signalling in the modulation of immune responses by passive antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Fc receptors as potential targets for the treatment of allergy, autoimmune disease and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Anti-cytokine Ab immune therapy: present status and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Molecular aspects of allergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Pathways for self-tolerance and the treatment of autoimmune diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Autoantibodies as predictors of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

New drugs for rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Role of cytokines in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

The soluble CD40 ligand sCD154 in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

An open study of B lymphocyte depletion in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Clinical applications of anti-CD20 antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

The relationship of FcgammaRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Rituximab: expanding role in therapy for lymphomas and autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Clinical trials of antibody therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Monoclonal antibodies as therapeutic agents for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Oncogenic growth factor receptors: implications for signal transduction therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Trastuzumab (Herceptin) enhances class I-restricted antigen presentation recognized by HER-2/neu-specific T cytotoxic lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Immunotherapeutic perspective for bispecific antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Bispecific antibodies targeting cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Recombinant soluble human Fc gamma RII: production, characterization, and inhibition of the Arthus reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Genetic control of collagen-induced arthritis in a cross with NOD and C57BL/10 mice is dependent on gene regions encoding complement factor 5 and FcgammaRIIb and is not associated with loci controlling diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Fcgamma receptors on mast cells: activatory and inhibitory regulation of mediator release

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Polymorphisms of the Fc gamma receptor type IIB gene are not associated with systemic lupus erythematosus in the Swedish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Immune thrombocytopenic purpura

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Immunomodulatory action of intravenous immunoglobulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

IVIG--mechanisms of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

IVIg-mediated amelioration of murine ITP via FcgammaRIIB is independent of SHIP1, SHP-1, and Btk activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Prevention of systemic lupus erythematosus in MRL/lpr mice by administration of an immunoglobulin-binding peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Synthesis and receptor binding of IgG1 peptides derived from the IgG Fc region

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Structure based design and characterization of peptides that inhibit IgE binding to its high-affinity receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

Immunisation against heterologous type II collagen induces arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.169

21 January 2018

Identifiers

DOI

10.1517/14728222.9.1.169

1 reference

12 August 2017

1 reference