(Q34220979)

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LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients (English)

1 reference

Europe PubMed Central

31 July 2017

1 reference

based on heuristic

inferred from title

9

object named as

Kelly K Hunt

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Europe PubMed Central

31 July 2017

Gordon B. Mills

8

object named as

Gordon B Mills

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Europe PubMed Central

31 July 2017

author name string

MyLinh T Duong

1

1 reference

Europe PubMed Central

31 July 2017

Said Akli

2

1 reference

Europe PubMed Central

31 July 2017

Caimiao Wei

3

1 reference

Europe PubMed Central

31 July 2017

Hannah F Wingate

4

1 reference

Europe PubMed Central

31 July 2017

Wenbin Liu

5

1 reference

Europe PubMed Central

31 July 2017

Yiling Lu

6

1 reference

Europe PubMed Central

31 July 2017

Min Yi

7

1 reference

Europe PubMed Central

31 July 2017

Khandan Keyomarsi

10

1 reference

Europe PubMed Central

31 July 2017

publication date

29 March 2012

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

31 July 2017

8

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Europe PubMed Central

31 July 2017

3

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Europe PubMed Central

31 July 2017

e1002538

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Europe PubMed Central

31 July 2017

copyright license

Creative Commons Attribution 4.0 International

29 March 2012

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April 2022 Public Data File from Crossref

copyright status

0 references

Targeting low molecular weight cyclin E (LMW-E) in breast cancer.

1 reference

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Cdk2 is required for breast cancer mediated by the low-molecular-weight isoform of cyclin E

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5 July 2018

Low molecular weight cyclin E overexpression shortens mitosis, leading to chromosome missegregation and centrosome amplification

1 reference

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5 July 2018

A novel interaction between HER2/neu and cyclin E in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315462

5 July 2018

Low-molecular-weight cyclin E can bypass letrozole-induced G1 arrest in human breast cancer cells and tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315462

5 July 2018

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

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Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

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Low molecular weight cyclin E is specific in breast cancer and is associated with mechanisms of tumor progression

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Functional proteomic profiling of AML predicts response and survival

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Autophagy: a novel mechanism of synergistic cytotoxicity between doxorubicin and roscovitine in a sarcoma model.

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Prognostic breast cancer signature identified from 3D culture model accurately predicts clinical outcome across independent datasets

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Sensitivity of Hodgkin's lymphoma cell lines to the cell cycle inhibitor roscovitine.

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The third dimension bridges the gap between cell culture and live tissue

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The MAPK(ERK-1,2) pathway integrates distinct and antagonistic signals from TGFalpha and FGF7 in morphogenesis of mouse mammary epithelium

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Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

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Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer

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Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo

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Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1

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Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes.

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5 July 2018

The tumor-specific hyperactive forms of cyclin E are resistant to inhibition by p21 and p27.

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Regulation of cyclin E protein levels through E2F-mediated inhibition of degradation

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5 July 2018

Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315462

5 July 2018

JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315462

5 July 2018

Cyclin E and survival in patients with breast cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315462

5 July 2018

beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315462

5 July 2018

Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition

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5 July 2018

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315462

5 July 2018

Tumor-specific proteolytic processing of cyclin E generates hyperactive lower-molecular-weight forms

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5 July 2018

Novel splice variants of cyclin E with altered substrate specificity

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5 July 2018

Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315462

5 July 2018

Processing of cyclin E differs between normal and tumor breast cells

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5 July 2018

Expression of cyclin E and the cyclin-dependent kinase inhibitor p27 in malignant lymphomas-prognostic implications.

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The role of cyclin E in cell proliferation, development and cancer

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5 July 2018

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

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5 July 2018

Less expression of cyclin E in cutaneous squamous cell carcinomas than in benign and premalignant keratinocytic lesions

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5 July 2018

Cyclin E, a redundant cyclin in breast cancer

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5 July 2018

Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

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5 July 2018

Cyclin E/Cdk2 activity is controlled by different mechanisms in the G0 and G1 phases of the cell cycle

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5 July 2018

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

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5 July 2018

Regulation of cyclin E transcription by E2Fs and retinoblastoma protein

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Redundant cyclin overexpression and gene amplification in breast cancer cells

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Mammalian G1 cyclins

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Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer

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Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture.

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Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types

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Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane.

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Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

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Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

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5 July 2018

Prognostic value of cyclin E and p53 expression in gastric carcinoma

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21 January 2018

Differential regulation of elafin in normal and tumor-derived mammary epithelial cells is mediated by CCAAT/enhancer binding protein beta.

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The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

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21 January 2018

Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002538

21 January 2018

Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor

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https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002538

21 January 2018

Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis

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21 January 2018

Nonparametric Estimation from Incomplete Observations

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https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002538

21 January 2018

Deregulation of cyclin E in breast cancer

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PGEN.1002538

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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