(Q34227712)

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Hypoxia suppresses cylindromatosis (CYLD) expression to promote inflammation in glioblastoma: possible link to acquired resistance to anti-VEGF therapy.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071012%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Hypoxia suppresses cylindromatosis (CYLD) expression to promote inflammation in glioblastoma: possible link to acquired resistance to anti-VEGF therapy (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071012%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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Mitsuhiro Hayashi

5

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10 March 2020

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Jianying Guo

1

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10 March 2020

Satoru Shinriki

2

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10 March 2020

Yu Su

3

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10 March 2020

Takuya Nakamura

4

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10 March 2020

Yukimoto Tsuda

6

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10 March 2020

Yoshitaka Murakami

7

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10 March 2020

Masayoshi Tasaki

8

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10 March 2020

Takuichiro Hide

9

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10 March 2020

Tatsuya Takezaki

10

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10 March 2020

Jun-Ichi Kuratsu

11

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10 March 2020

Satoshi Yamashita

12

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10 March 2020

Mitsuharu Ueda

13

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10 March 2020

Jian-Dong Li

14

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10 March 2020

Hirofumi Jono

16

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10 March 2020

Yukio Ando

15

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10 March 2020

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1 August 2014

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10 March 2020

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10 March 2020

5

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10 March 2020

15

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10 March 2020

6353-6364

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10 March 2020

CYLD downregulation is correlated with tumor development in patients with hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

Clinical significance of CYLD downregulation in breast cancer

1 reference

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5 July 2018

Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma.

1 reference

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5 July 2018

Acquired resistance to anti-VEGF therapy in glioblastoma is associated with a mesenchymal transition

1 reference

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5 July 2018

Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance

1 reference

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5 July 2018

Interleukins in glioblastoma pathophysiology: implications for therapy.

1 reference

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5 July 2018

TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets.

1 reference

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Controlling escape from angiogenesis inhibitors

1 reference

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5 July 2018

Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype

1 reference

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5 July 2018

Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications

1 reference

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5 July 2018

Glioblastoma--a moving target.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

Snail1 mediates hypoxia-induced melanoma progression

1 reference

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Targeting glioma stem cells: a novel framework for brain tumors

1 reference

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5 July 2018

Targeting hypoxia in cancer therapy

1 reference

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5 July 2018

Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

Hypoxia and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme

1 reference

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5 July 2018

The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

Mechanism of hypoxia-induced NF-kappaB.

1 reference

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5 July 2018

Chemokines and glioma: invasion and more

1 reference

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5 July 2018

Ubiquitin chain cleavage: CYLD at work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

1 reference

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5 July 2018

Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma

1 reference

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5 July 2018

Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy

1 reference

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5 July 2018

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

Inactivation of the CYLD deubiquitinase by HPV E6 mediates hypoxia-induced NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171635

5 July 2018

New regulators of NF-kappaB in inflammation

1 reference

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5 July 2018

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

1 reference

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5 July 2018

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

1 reference

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1 reference

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5 July 2018

Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan

1 reference

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1 reference

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5 July 2018

Interleukin-6 gene amplification and shortened survival in glioblastoma patients.

1 reference

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1 reference

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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

1 reference

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Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.

1 reference

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1 reference

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Antiangiogenic therapy and tumor progression

1 reference

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The biology of VEGF and its receptors

1 reference

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Identification of the familial cylindromatosis tumour-suppressor gene

1 reference

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Genetic profile of gliosarcomas

1 reference

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An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy

1 reference

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1 reference

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1 reference

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28 October 2018

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10.18632/ONCOTARGET.2216

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071012%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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Europe PubMed Central

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10 March 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071012%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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