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Molecular controls of antigen receptor clustering and autoimmunity
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Molecular controls of antigen receptor clustering and autoimmunity
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
author
Josef Penninger
series ordinal
2
object named as
J M Penninger
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
author name string
C Krawczyk
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
publication date
1 May 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
published in
Trends in Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
volume
11
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
page(s)
212-220
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
issue
5
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
cites work
The thymic microenvironment.
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Signaling through scaffold, anchoring, and adaptor proteins
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Three-dimensional segregation of supramolecular activation clusters in T cells
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7 January 2021
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T lymphocyte costimulation mediated by reorganization of membrane microdomains
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A cell culture model for T lymphocyte clonal anergy
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A receptor/cytoskeletal movement triggered by costimulation during T cell activation
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7 January 2021
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Making the T cell receptor go the distance: a topological view of T cell activation
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Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor
1 reference
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Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction
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Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation.
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Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes
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Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription
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Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells
1 reference
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7 January 2021
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Integrin-dependent tyrosine phosphorylation and growth regulation by Vav
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7 January 2021
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Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1
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7 January 2021
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Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav
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7 January 2021
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Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
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inferred from DOI database lookup
Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells
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7 January 2021
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Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs
1 reference
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Crossref
reference URL
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Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential
1 reference
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Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins
1 reference
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7 January 2021
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Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation
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Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
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7 January 2021
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Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cbl-b regulates the CD28 dependence of T-cell activation.
1 reference
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7 January 2021
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The oncogene product Vav is a crucial regulator of primary cytotoxic T cell responses but has no apparent role in CD28-mediated co-stimulation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus
1 reference
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Crossref
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Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex
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A homochiral metal-organic porous material for enantioselective separation and catalysis
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of actin assembly
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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based on heuristic
inferred from DOI database lookup
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of actin polymerization by Arp2/3 complex and WASp/Scar proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
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Biochemistry. Ubiquitination--more than two to tango
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
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v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The c-cbl proto-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites.
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
cbl-3: a new mammalian cbl family protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cbl-b inhibits epidermal growth factor receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement of lymphocyte responsiveness by a gain-of-function mutation of ZAP-70.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered thymic positive selection and intracellular signals in Cbl-deficient mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential requirements for survival and proliferation of CD8 naïve or memory T cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of beta-catenin-lymphocyte enhancer-binding factor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0962-8924(01)01981-X
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
PubMed ID
11316610
1 reference
stated in
Europe PubMed Central
PubMed ID
11316610
retrieved
31 July 2017
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