(Q34228582)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Cosmin Mihai

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Shengying Bao

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Ju-Ping Lai

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Daren L Knoell

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

publication date

28 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Lung Cellular and Molecular Physiology

15 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

302

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

L287-99

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

15 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3289272/fullTextXML

inferred from PubMed Central ID database lookup

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5 July 2018

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Cyclic mechanical stretch decreases cell migration by inhibiting phosphatidylinositol 3-kinase- and focal adhesion kinase-mediated JNK1 activation

5 July 2018

1 reference

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5 July 2018

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Mechanical stretch decreases FAK phosphorylation and reduces cell migration through loss of JIP3-induced JNK phosphorylation in airway epithelial cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Localized elasticity measured in epithelial cells migrating at a wound edge using atomic force microscopy

5 July 2018

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A chemical method for fast and sensitive detection of DNA synthesis in vivo

5 July 2018

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Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair

5 July 2018

1 reference

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Influence of airway diameter and cell confluence on epithelial cell injury in an in vitro model of airway reopening.

5 July 2018

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Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective.

5 July 2018

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PTEN, the Achilles' heel of myocardial ischaemia/reperfusion injury?

5 July 2018

1 reference

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Cell adaptation to a physiologically relevant ECM mimic with different viscoelastic properties

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Relationship between apical membrane elasticity and stress fiber organization in fibroblasts analyzed by fluorescence and atomic force microscopy.

5 July 2018

1 reference

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The regulation of cell migration by PTEN.

5 July 2018

1 reference

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Protection of epithelial cells by keratinocyte growth factor signaling

5 July 2018

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Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Intracellular mechanics of migrating fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Contribution of cellular contractility to spatial and temporal variations in cellular stiffness.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Keratinocyte growth factor induces Akt kinase activity and inhibits Fas-mediated apoptosis in A549 lung epithelial cells

5 July 2018

1 reference

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RhoA and Rac1 are both required for efficient wound closure of airway epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Dystroglycan, a scaffold for the ERK-MAP kinase cascade

5 July 2018

1 reference

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Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation

5 July 2018

1 reference

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Cell migration: integrating signals from front to back

5 July 2018

1 reference

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Abnormal PTEN expression in portal hypertensive gastric mucosa: A key to impaired PI 3‐kinase/Akt activation and delayed injury healing?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Integrin alpha4beta1 regulates migration across basement membranes by lung fibroblasts: a role for phosphatase and tensin homologue deleted on chromosome 10

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia

5 July 2018

1 reference

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Mechanisms of surface-tension-induced epithelial cell damage in a model of pulmonary airway reopening

5 July 2018

1 reference

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PKB binding proteins. Getting in on the Akt.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

The phosphoinositide 3-kinase pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Regulation of substrate adhesion dynamics during cell motility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Raf-MEK-Erk cascade in anoikis is controlled by Rac1 and Cdc42 via Akt.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Mechanical behavior in living cells consistent with the tensegrity model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Activated Akt protects the lung from oxidant-induced injury and delays death of mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Cell movement is guided by the rigidity of the substrate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Cell cycle arrest by the PTEN tumor suppressor is target cell specific and may require protein phosphatase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Rho GTPases control polarity, protrusion, and adhesion during cell movement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

5 July 2018

Atomic force microscope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Dimensional and mechanical dynamics of active and stable edges in motile fibroblasts investigated by using atomic force microscopy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Cell locomotion and focal adhesions are regulated by substrate flexibility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Cell migration: a physically integrated molecular process

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Rho, rac and cdc42 GTPases: regulators of actin structures, cell adhesion and motility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Traction patterns of tumor cells.

5 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00037.2011

Targeting of the Akt/PKB kinase to the actin skeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00037.2011

Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00037.2011

Distinct signalling particles containing ERK/MEK and B-Raf in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00037.2011

MEK mediates v-Src-induced disruption of the actin cytoskeleton via inactivation of the Rho-ROCK-LIM kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00037.2011

Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00037.2011

Physical forces during collective cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00037.2011

Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00037.2011

Geometric confinement influences cellular mechanical properties II -- intracellular variances in polarized cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

An in vitro model of differentiated human airway epithelia. Methods for establishing primary cultures.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289272

Role of deformation-induced lipid trafficking in the prevention of plasma membrane stress failure

28 October 2018

1 reference

12 December 2020

Deformation-induced injury of alveolar epithelial cells. Effect of frequency, duration, and amplitude

1 reference

12 December 2020

Stretch induces cytokine release by alveolar epithelial cells in vitro

1 reference

12 December 2020

Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells

1 reference

12 December 2020

Measurement of stretch-induced loss of alveolar epithelial barrier integrity with a novel in vitro method

1 reference

12 December 2020

10.1152/AJPLUNG.00037.2011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037358%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference