(Q34230513)

31 July 2017

title

Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction (English)

1 reference

31 July 2017

1 reference

Clemens-Martin Wendtner

6

object named as

Clemens-Martin Wendtner

1 reference

31 July 2017

Peter D Kurktschiev

1

1 reference

31 July 2017

Bijan Raziorrouh

2

1 reference

31 July 2017

Winfried Schraut

3

1 reference

31 July 2017

Markus Backmund

4

1 reference

31 July 2017

Martin Wächtler

5

1 reference

31 July 2017

Bertram Bengsch

7

1 reference

31 July 2017

Robert Thimme

8

1 reference

31 July 2017

Gerald Denk

9

1 reference

31 July 2017

Reinhart Zachoval

10

1 reference

31 July 2017

Andrea Dick

11

1 reference

31 July 2017

Michael Spannagl

12

1 reference

31 July 2017

Jürgen Haas

13

1 reference

31 July 2017

Helmut M Diepolder

14

1 reference

31 July 2017

Maria-Christina Jung

15

1 reference

31 July 2017

Norbert H Gruener

16

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31 July 2017

language of work or name

English

0 references

publication date

15 September 2014

1 reference

Journal of Experimental Medicine

31 July 2017

published in

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31 July 2017

volume

211

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31 July 2017

issue

10

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31 July 2017

page(s)

2047-2059

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The third signal cytokine IL-12 rescues the anti-viral function of exhausted HBV-specific CD8 T cells

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Cytokine-mediated programmed proliferation of virus-specific CD8(+) memory T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Hepatitis C virus core selectively suppresses interleukin-12 synthesis in human macrophages by interfering with AP-1 activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Antigen-driven effector CD8 T cell function regulated by T-bet

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Hepatitis C virus infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Analysis of successful immune responses in persons infected with hepatitis C virus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

A novel transcription factor, T-bet, directs Th1 lineage commitment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

A phase I/II study of recombinant human interleukin-12 in patients with chronic hepatitis C.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

A pilot study of recombinant interleukin-2 for treatment of chronic hepatitis C.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Clinical aspects of hepatitis B virus infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Purification, fractionation and assay of antibody-dependent lymphocytic effector cells (K cells) in human blood

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection

6 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20131333

CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20131333

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20131333

Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20131333

Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20131333

Double-blind, randomized controlled trial of interleukin-2 treatment of chronic hepatitis B.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172217

A phase I/II study of recombinant human interleukin-12 in patients with chronic hepatitis B

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25225458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Common HLA-B8-DR3 haplotype in Northern India is different from that found in Europe

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25225458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IL-12 up-regulates T-bet independently of IFN-gamma in human CD4+ T cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25225458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20131333

1 reference

31 July 2017

1 reference

31 July 2017

1 reference