(Q34233880)

31 July 2017

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title

Genomic instability: potential contributions to tumour and normal tissue response, and second tumours, after radiotherapy (English)

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Adaptive radiation therapy

31 July 2017

main subject

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author name string

Hendry JH

series ordinal

1

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31 July 2017

publication date

1 May 2001

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Radiotherapy and Oncology

31 July 2017

published in

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31 July 2017

volume

59

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31 July 2017

issue

2

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31 July 2017

page(s)

117-126

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BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair

31 July 2017

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Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome

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Molecular genotyping shows that ataxia-telangiectasia heterozygotes are predisposed to breast cancer

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7 January 2021

Relationship between in vitro chromosomal radiosensitivity of peripheral blood lymphocytes and the expression of normal tissue damage following radiotherapy for breast cancer

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Radiation-induced genomic instability: a paradigm-breaking phenomenon and its relevance to environmentally induced cancer

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Breast cancer and other second neoplasms after childhood Hodgkin's disease

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7 January 2021

The immunohistochemical expression of DNA-PKcs and Ku (p70/p80) in head and neck cancers: relationships with radiosensitivity

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7 January 2021

The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy

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7 January 2021

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer

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7 January 2021

Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair.

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7 January 2021

Describing patients' normal tissue reactions: concerning the possibility of individualising radiotherapy dose prescriptions based on potential predictive assays of normal tissue radiosensitivity. Steering Committee of the BioMed2 European Union Conc

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7 January 2021

Comparison of DNA repair protein expression and activities between human fibroblast cell lines with different radiosensitivities

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7 January 2021

Lack of correlation between ATM protein expression and tumour cell radiosensitivity

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7 January 2021

Delayed Reproductive Death in X-irradiated Chinese Hamster Ovary Cells

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7 January 2021

Contribution of Lethal Mutations to Excision Assays for Tumour Cell Survival

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7 January 2021

Induction of lethal mutations in experimental tumours after single and fractionated irradiations in vivo

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7 January 2021

Re-irradiation of mouse skin: similarity of dose reductions for healing and macrocolony endpoints

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7 January 2021

Radiosensitivity in ataxia-telangiectasia

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7 January 2021

Multiple naevoid basal cell carcinoma syndrome (Gorlin's syndrome)

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7 January 2021

Second cancers after Hodgkin's disease in childhood

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7 January 2021

Transgenerational mutation by radiation

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7 January 2021

Radiation-induced germline instability at minisatellite loci

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7 January 2021

Testing for the breast cancer predisposition gene, BRCA1.

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7 January 2021

Emergence of genetic instability in children treated for leukemia.

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7 January 2021

Expression of lethal mutations in progeny of irradiated mammalian cells

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7 January 2021

Second primary tumors following radiotherapy for childhood cancer

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7 January 2021

Enhanced response to the induction of sister chromatid exchange by gamma radiation in neurofibromatosis

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7 January 2021

The tolerance of mouse tails to necrosis after repeated irradiation with X rays

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7 January 2021

p53 deficiency sensitizes clonogenic cells to irradiation in the large but not the small intestine

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7 January 2021

Implications of delayed reproductive cell death (lethal mutations/genomic instability) for the interpretation of tissue responses.

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7 January 2021

A cellular analysis of residual hemopoietic deficiencies in mice after 4 repeated doses of 4.5 gray X rays

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7 January 2021

Second malignant neoplasms in children treated for rhabdomyosarcoma. Intergroup Rhabdomyosarcoma Study Committee

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7 January 2021

Enhanced DNA repair and tolerance of DNA damage associated with resistance to cis-diammine-dichloroplatinum (II) after in vitro exposure of a human teratoma cell line to fractionated X-irradiation.

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7 January 2021

The tolerance of re-irradiation of heavily irradiated human skin

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7 January 2021

Genetic complementation analysis of ataxia telangiectasia and Nijmegen breakage syndrome: a survey of 50 patients

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7 January 2021

Abnormal radiosensitivity of lymphocytes from breast cancer patients with excessive normal tissue damage after radiotherapy: chromosome aberrations after low dose-rate irradiation

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7 January 2021

Radiation-induced chromosomal instability in human fibroblasts: temporal effects and the influence of radiation quality

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7 January 2021

p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis

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7 January 2021

A correlation between residual radiation-induced DNA double-strand breaks in cultured fibroblasts and late radiotherapy reactions in breast cancer patients

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7 January 2021

Induction of genetic instability by ionizing radiation

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7 January 2021

Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells

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7 January 2021

The modelled benefits of individualizing radiotherapy patients' dose using cellular radiosensitivity assays with inherent variability

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7 January 2021

Apoptosis induced by γ-irradiation, but not CD4 ligation, of peripheral T lymphocytesin vivo is p53-dependent

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7 January 2021

Plating efficiency as a function of time postirradiation: evidence for the delayed expression of lethal mutations.

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7 January 2021

On the recall phenomenon

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7 January 2021

A role for genomic instability in cellular radioresistance?

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7 January 2021

Expression of delayed toxicity and lethal mutations in the progeny of human cells surviving exposure to radiation and other environmental mutagens

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7 January 2021

Dose- and time-response relationships for lethal mutations and chromosomal instability induced by ionizing radiation in an immortalized human keratinocyte cell line

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7 January 2021

Lethal mutations and genomic instability

1 reference

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7 January 2021

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Sequence analysis of the ATM gene in 20 patients with RTOG grade 3 or 4 acute and/or late tissue radiation side effects

1 reference

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7 January 2021

Postirradiation expression of lethal mutations in an immortalized human keratinocyte cell line

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7 January 2021

Cytogenetic response to G2-phase X irradiation in relation to DNA repair and radiosensitivity in a cancer-prone family with Li-Fraumeni syndrome

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7 January 2021

Radiation-induced thyroid neoplasms: evidence for familial susceptibility factors

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7 January 2021

Induction of chromosomal instability in human mammary cells by neutrons and gamma rays

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Cell cycles in cell hierarchies

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7 January 2021

Rare microsatellite polymorphisms in the DNA repair genes XRCC1, XRCC3 and XRCC5 associated with cancer in patients of varying radiosensitivity

1 reference

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7 January 2021

Interactions in recovery and in residual injury from sequential treatments of mouse haemopoietic and stromal marrow cell populations, using X-rays, cyclophosphamide and busulphan

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Testing for mutations of the ataxia telangiectasia gene in radiosensitive breast cancer patients

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Incidence of second neoplasms in patients with bilateral retinoblastoma

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7 January 2021

Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer?

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7 January 2021

Chromosomal instability in in vivo radiation exposed subjects

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7 January 2021

Cytogenetic responses to G2 phase x-irradiation of cells from retinoblastoma patients

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Chromosomal radiosensitivity, cancer predisposition and response to radiotherapy

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7 January 2021

Genetic predisposition in breast cancer

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7 January 2021

High yields of lethal mutations in somatic mammalian cells that survive ionizing radiation

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7 January 2021

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

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7 January 2021

Heterozygosity for mutations in the ataxia telangiectasia gene is not a major cause of radiotherapy complications in breast cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Fibroblasts from Li-Fraumeni patients are resistant to low dose-rate irradiation

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

The basal cell nevus syndrome.Disasters occurring among a series of 36 patients

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Multiple schwannomas and meningiomas associated with irradiation in childhood

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Further delineation of the Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Manifestations and mechanisms of radiation-induced genomic instability in V-79 Chinese hamster cells

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Radiation-induced instability and its relation to radiation carcinogenesis

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Enhanced radiation late effects and cellular radiation sensitivity in an ATM heterozygous breast cancer patient

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Adriamycin-induced recall of radiation pneumonitis and epilation in lung and hair follicles of mouse

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

The self renewal probability of hemopoietic stem cells

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Gamma-ray-induced cell killing and chromosome abnormalities in the bone marrow of p53-deficient mice

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Insights into the functions of BRCA1 and BRCA2.

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

The intrinsic radiosensitivity of normal and tumour cells

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Cell cycle arrest defect in Li-Fraumeni Syndrome: a mechanism of cancer predisposition?

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Expression of Ku70 correlates with survival in carcinoma of the cervix.

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

The repair of double-strand DNA breaks correlates with radiosensitivity of L5178Y-S and L5178Y-R cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk

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https://api.crossref.org/works/10.1016%2FS0167-8140%2801%2900285-7

7 January 2021

10.1016/S0167-8140(01)00285-7

Identifiers

DOI

1 reference

31 July 2017

1 reference