(Q34238083)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

chronic obstructive pulmonary disease

17 January 2020

main subject

0 references

author

Matthew D Layne

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

7

Pawel Sliwinski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

13

Barbara J Klanderman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

21

Augustine M K Choi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Xiaobo Zhou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Rebecca M Baron

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Megan Hardin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Michael H Cho

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jan Zielinski

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Iwona Hawrylkiewicz

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Craig P Hersh

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

John D Mancini

9

1 reference

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17 January 2020

Ke Lu

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Derek Thibault

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Amy L Donahue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Bernard Rosner

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Benjamin A Raby

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Quan Lu

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Adriana M Geldart

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Mark A Perrella

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Scott T Weiss

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Edwin K Silverman

22

1 reference

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17 January 2020

publication date

2 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

21

1 reference

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17 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

1325-1335

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

Births: final data for 2008.

17 January 2020

cites work

1 reference

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Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function

6 July 2018

1 reference

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9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

6 July 2018

1 reference

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Epigenetic silencing of spermatocyte-specific and neuronal genes by SUMO modification of the transcription factor Sp3.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Clld7, a candidate tumor suppressor on chromosome 13q14, regulates pathways of DNA damage/repair and apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Expression and epigenetic modulation of sonic hedgehog-GLI1 pathway genes in neuroblastoma cell lines and tumors.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Mediator and cohesin connect gene expression and chromatin architecture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

6 July 2018

1 reference

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Genomewide association studies and assessment of the risk of disease

6 July 2018

1 reference

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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Distamycin A inhibits HMGA1-binding to the P-selectin promoter and attenuates lung and liver inflammation during murine endotoxemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Variants in FAM13A are associated with chronic obstructive pulmonary disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Long-range enhancers on 8q24 regulate c-Myc

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Genome-wide association study identifies five loci associated with lung function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Hedgehog-interacting protein is a COPD susceptibility gene: the Rotterdam Study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Genomic views of distant-acting enhancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Clinical practice. Alpha1-antitrypsin deficiency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Long-range regulation at the SOX9 locus in development and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Fast and accurate short read alignment with Burrows-Wheeler transform

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

A genome-wide association study of pulmonary function measures in the Framingham Heart Study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Down-regulation of hedgehog-interacting protein through genetic and epigenetic alterations in human hepatocellular carcinoma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Genome-wide association analysis identifies 20 loci that influence adult height

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

High-resolution profiling of histone methylations in the human genome

6 July 2018

1 reference

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Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Complement factor H polymorphism in age-related macular degeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Reduction of nitric oxide synthase 2 expression by distamycin A improves survival from endotoxemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Combined activities of hedgehog signaling inhibitors regulate pancreas development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Epidemiology Standardization Project (American Thoracic Society)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3284120

Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb.

6 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR569

A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR569

3D chromatin regulation of Sonic hedgehog in the limb buds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR569

Transcriptional silencing of hedgehog-interacting protein by CpG hypermethylation and chromatic structure in human gastrointestinal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR569

Siblings of patients with severe chronic obstructive pulmonary disease have a significant risk of airflow obstruction

21 January 2018

1 reference

12 December 2020

Mapping chromatin interactions by chromosome conformation capture

1 reference

12 December 2020

Chromosome 4q31 locus in COPD is also associated with lung cancer

1 reference

12 December 2020

Deaths: preliminary data for 2008.

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDR569

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140090%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

22140090

1 reference