(Q34239748)

31 July 2017

title

Endocytosis and intracellular trafficking contribute to necrotic neurodegeneration in C. elegans (English)

1 reference

Calpain clp-1 CELE_C06G4.2

31 July 2017

main subject

Caenorhabditis elegans

0 references

1 reference

Phosphatidylinositol-binding clathrin assembly protein unc-11 CELE_C32E8.10

1 reference

Synaptotagmin-1 CELE_F31E8.2

1 reference

Dynamin CELE_C02C6.1

1 reference

Synaptojanin CELE_JC8.10

1 reference

Kinesin-like protein unc-104 CELE_C52E12.2

1 reference

Protein lgg-1 CELE_C32D5.9

1 reference

AP-2 complex subunit mu CELE_R160.1

1 reference

Kinesin heavy chain CELE_R05D3.7

1 reference

Endophilin-A homolog CELE_T04D1.3

1 reference

1 reference

Nektarios Tavernarakis

series ordinal

2

1 reference

31 July 2017

Kostoula Troulinaki

1

1 reference

31 July 2017

language of work or name

English

0 references

publication date

9 December 2011

1 reference

31 July 2017

1 reference

31 July 2017

volume

31

1 reference

31 July 2017

issue

3

1 reference

31 July 2017

page(s)

654-666

1 reference

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Autophagy and cell death in model organisms

6 July 2018

1 reference

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Role of axonal transport in neurodegenerative diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME-4, a coated-pit protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Autophagy and cell death in Caenorhabditis elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Endophilin I expression is increased in the brains of Alzheimer disease patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

A novel requirement for C. elegans Alix/ALX-1 in RME-1-mediated membrane transport

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Autophagosome formation: core machinery and adaptations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Autophagy is required for necrotic cell death in Caenorhabditis elegans.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Mechanism of endophilin N-BAR domain-mediated membrane curvature

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Axonal transport and neurodegenerative disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Stimulation of dynamin GTPase activity by amphiphysin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Rab conversion as a mechanism of progression from early to late endosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

The vacuolar H+ -ATPase mediates intracellular acidification required for neurodegeneration in C. elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Molecular motors and mechanisms of directional transport in neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Endocytosis by random initiation and stabilization of clathrin-coated pits

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

The stimulatory action of amphiphysin on dynamin function is dependent on lipid bilayer curvature

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Ca2+-dependent proteases in ischemic neuronal death: a conserved 'calpain-cathepsin cascade' from nematodes to primates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

BAR domains as sensors of membrane curvature: the amphiphysin BAR structure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Clathrin-dependent endocytosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Class III phosphoinositide 3-kinase--Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Autophagy genes are essential for dauer development and life-span extension in C. elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Synaptotagmin I, a Ca2+ sensor for neurotransmitter release

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

The biochemistry of neuronal necrosis: rogue biology?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Genome-wide RNAi screening in Caenorhabditis elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Death by necrosis. Uncontrollable catastrophe, or is there order behind the chaos?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Amphiphysins: raising the BAR for synaptic vesicle recycling and membrane dynamics. Bin-Amphiphysin-Rvsp

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapse

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2+) release from the endoplasmic reticulum

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Studies of synaptic vesicle endocytosis in the nematode C. elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Clathrin-mediated endocytosis: membrane factors pull the trigger

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

The AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Endocytosis and signaling cascades: a close encounter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Rab proteins as membrane organizers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Synaptotagmin I functions as a calcium regulator of release probability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

A conserved clathrin assembly motif essential for synaptic vesicle endocytosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Synaptic vesicle endocytosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Cloning by insertional mutagenesis of a cDNA encoding Caenorhabditis elegans kinesin heavy chain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Identification of a putative structural gene for cathepsin D in Caenorhabditis elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.447

Endophilin/SH3p4 is required for the transition from early to late stages in clathrin-mediated synaptic vesicle endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.447

Endophilin Is Required for Synaptic Vesicle Endocytosis by Localizing Synaptojanin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.447

Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.447

Influence of autophagy genes on ion-channel-dependent neuronal degeneration in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.447

A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.447

Truncations of amphiphysin I by calpain inhibit vesicle endocytosis during neural hyperexcitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.447

Amphiphysins: Raising the BAR for Synaptic Vesicle Recycling and Membrane Dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.447

Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

A role for the clathrin assembly domain of AP180 in synaptic vesicle endocytosis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

The calcium-binding site of clathrin light chains.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273398

Neuropathology of degenerative cell death in Caenorhabditis elegans

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22157748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2011.447

1 reference

31 July 2017

1 reference

31 July 2017

1 reference