(Q34242995)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Development of a pharmaceutical hepatotoxicity biomarker panel using a discovery to targeted proteomics approach (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

William M Gallagher

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Stephen R. Pennington

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Christine A Miller

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Alexandra Sposny

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Phillip Hewitt

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Martin Wells

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

publication date

23 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

Molecular & Cellular Proteomics

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

394-410

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

mProphet: automated data processing and statistical validation for large-scale SRM experiments

29 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Sequence tagging reveals unexpected modifications in toxicoproteomics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Options and considerations when selecting a quantitative proteomics strategy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

ProteomeCommons.org collaborative annotation and project management resource integrated with the Tranche repository

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

The discovery and development of proteomic safety biomarkers for the detection of drug-induced liver toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Use of SELDI MS to discover and identify potential biomarkers of toxicity in InnoMed PredTox: a multi-site, multi-compound study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Role of spectral counting in quantitative proteomics.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Performance of novel kidney biomarkers in preclinical toxicity studies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

A guided tour of the Trans-Proteomic Pipeline

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Free computational resources for designing selected reaction monitoring transitions.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

High-throughput generation of selected reaction-monitoring assays for proteins and proteomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Empirical Bayes analysis of quantitative proteomics experiments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Directed mass spectrometry: towards hypothesis-driven proteomics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Correlation between y-type ions observed in ion trap and triple quadrupole mass spectrometers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Targeted proteomic strategy for clinical biomarker discovery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Expediting the development of targeted SRM assays: using data from shotgun proteomics to automate method development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Testing significance relative to a fold-change threshold is a TREAT.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

BioMart--biological queries made easy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Selected reaction monitoring for quantitative proteomics: a tutorial

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

An integrated, directed mass spectrometric approach for in-depth characterization of complex peptide mixtures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Creation of a digital slide and tissue microarray resource from a multi-institutional predictive toxicology study in the rat: an initial report from the PredTox group

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

PeptideAtlas: a resource for target selection for emerging targeted proteomics workflows

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Public consortium efforts in toxicogenomics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Targeted quantitative analysis of Streptococcus pyogenes virulence factors by multiple reaction monitoring

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Comparative LC-MS: a landscape of peaks and valleys

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Database resources of the National Center for Biotechnology Information

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Analysis of peptide MS/MS spectra from large-scale proteomics experiments using spectrum libraries

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

General framework for developing and evaluating database scoring algorithms using the TANDEM search engine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

A uniform proteomics MS/MS analysis platform utilizing open XML file formats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Toxicogenomics and systems toxicology: aims and prospects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Can the pharmaceutical industry reduce attrition rates?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

TANDEM: matching proteins with tandem mass spectra

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

A statistical model for identifying proteins by tandem mass spectrometry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

The human plasma proteome: history, character, and diagnostic prospects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Probability-based protein identification by searching sequence databases using mass spectrometry data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

KEGG: kyoto encyclopedia of genes and genomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Basic local alignment search tool

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412970

Integrated pipeline for mass spectrometry-based discovery and confirmation of biomarkers demonstrated in a mouse model of breast cancer.

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016493

Improving sensitivity by probabilistically combining results from multiple MS/MS search methodologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016493

Semisupervised model-based validation of peptide identifications in mass spectrometry-based proteomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016493

Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016493

Protocols of Two-Dimensional Difference Gel Electrophoresis to Investigate Mechanisms of Toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016493

Relative and absolute quantitative expression profiling of cytochromes P450 using isotope-coded affinity tags

21 January 2018

1 reference

12 December 2020

Omic profiling for drug safety assessment: current trends and public–private partnerships

1 reference

12 December 2020

Assessment of candidate biomarkers of drug-induced hepatobiliary injury in preclinical toxicity studies

1 reference

12 December 2020

EU Framework 6 Project: Predictive Toxicology (PredTox)—overview and outcome

1 reference

12 December 2020

Identifiers

DOI

10.1074/MCP.M111.016493

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527513%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

22527513

1 reference