(Q34246928)

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Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

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31 July 2017

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells (English)

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31 July 2017

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Kfir Lapid

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Shinya Oishi

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Hal E. Broxmeyer

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Hal E Broxmeyer

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Paul S. Frenette

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Paul S Frenette

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Aya Ludin

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Tsvee Lapidot

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Orit Kollet

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Alexander Kalinkovich

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Alexander Kalinkovich

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Tomer Itkin

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Ayelet Dar

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Amir Schajnovitz

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Amir Schajnovitz

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Melania Tesio

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Eike C Buss

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Wei-Ming Kao

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Michela Battista

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Neta Netzer Cohen

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Raanan Margalit

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Francoise Baleux

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Nobutaka Fujii

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Andre Larochelle

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Cynthia E Dunbar

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publication date

15 April 2011

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1286-1296

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31 July 2017

https://scigraph.springernature.com/pub.10.1038/leu.2011.62

0 references

The brain-bone-blood triad: traffic lights for stem-cell homing and mobilization

1 reference

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6 July 2018

Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells.

1 reference

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6 July 2018

Innate immunity as orchestrator of stem cell mobilization

1 reference

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6 July 2018

CXCR4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction

1 reference

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6 July 2018

S1P1 receptor directs the release of immature B cells from bone marrow into blood.

1 reference

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6 July 2018

Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization d

1 reference

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6 July 2018

Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

CCR2 and CXCR4 regulate peripheral blood monocyte pharmacodynamics and link to efficacy in experimental autoimmune encephalomyelitis

1 reference

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6 July 2018

Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands

1 reference

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6 July 2018

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization

1 reference

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6 July 2018

Stem cell regulation via dynamic interactions of the nervous and immune systems with the microenvironment

1 reference

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6 July 2018

Plasmin therapy enhances mobilization of HPCs after G-CSF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Stem-cell ecology and stem cells in motion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

The plasminogen fibrinolytic pathway is required for hematopoietic regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Haematopoietic stem cell release is regulated by circadian oscillations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR-4-dependent up-regulation of urokinase-type plasminogen activator receptor (uPAR, CD87) expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

A novel role of complement in mobilization: immunodeficient mice are poor granulocyte-colony stimulating factor mobilizers because they lack complement-activating immunoglobulins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

The multiple roles of osteoclasts in host defense: bone remodeling and hematopoietic stem cell mobilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

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Physiological migration of hematopoietic stem and progenitor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

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SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

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Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

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Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

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Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Ultrastructural morphometric study of efferent nerve terminals on murine bone marrow stromal cells, and the recognition of a novel anatomical unit: the "neuro-reticular complex".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4175714

6 July 2018

Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.62

21 January 2018

Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.62

21 January 2018

The CXCR4 antagonist 4F-benzoyl-TN14003 stimulates the recovery of the bone marrow after transplantation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.62

21 January 2018

Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.62

21 January 2018

A phase II study of plerixafor (AMD3100) plus G-CSF for autologous hematopoietic progenitor cell mobilization in patients with Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.62

21 January 2018

Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.62

21 January 2018

Decreased circulating progenitor cell number and failed mechanisms of stromal cell-derived factor-1alpha mediated bone marrow mobilization impair diabetic tissue repair

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.62

21 January 2018

Insights into the biology of mobilized hematopoietic stem/progenitor cells through innovative treatment schedules of the CXCR4 antagonist AMD3100.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.62

21 January 2018

Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.62

21 January 2018

uPAR-uPA-PAI-1 interactions and signaling: a vascular biologist's view

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the urokinase-type plasminogen activator receptor in hematopoietic stem cell mobilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil-derived MMP-9 mediates synergistic mobilization of hematopoietic stem and progenitor cells by the combination of G-CSF and the chemokines GRObeta/CXCL2 and GRObetaT/CXCL2delta4

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved mobilization of peripheral blood CD34+ cells and dendritic cells by AMD3100 plus granulocyte-colony-stimulating factor in non-Hodgkin's lymphoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulfated glycans induce rapid hematopoietic progenitor cell mobilization: evidence for selectin-dependent and independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catecholaminergic neurotransmitters regulate migration and repopulation of immature human CD34+ cells through Wnt signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/LEU.2011.62

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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