(Q34248457)

31 July 2017

title

UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation (English)

1 reference

31 July 2017

Gabriela Alexandru

5

0 references

Nicola T Wood

object named as

Nicola T Wood

4

0 references

author name string

Susanne Bandau

1

1 reference

31 July 2017

Axel Knebel

2

1 reference

31 July 2017

Zoe O Gage

3

1 reference

31 July 2017

publication date

26 April 2012

1 reference

31 July 2017

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31 July 2017

volume

10

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31 July 2017

page(s)

36

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A Dual E3 Mechanism for Rub1 Ligation to Cdc53

31 July 2017

cites work

1 reference

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Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ

6 July 2018

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Ubiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradation

6 July 2018

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

6 July 2018

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Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation

6 July 2018

1 reference

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Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

6 July 2018

1 reference

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UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

6 July 2018

1 reference

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Proteasome subunit Rpn13 is a novel ubiquitin receptor

6 July 2018

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UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

6 July 2018

1 reference

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Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation

6 July 2018

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Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.

6 July 2018

1 reference

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Cdc48p(Npl4p/Ufd1p) binds and segregates membrane-anchored/tethered complexes via a polyubiquitin signal present on the anchors

6 July 2018

1 reference

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Ubiquitin-binding domains

6 July 2018

1 reference

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The role of p97/Cdc48p in endoplasmic reticulum-associated degradation: from the immune system to yeast.

6 July 2018

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Integration of oxygen signaling at the consensus HRE.

6 July 2018

1 reference

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Global phosphoproteome of HT-29 human colon adenocarcinoma cells

6 July 2018

1 reference

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Ubiquitin-binding domains

6 July 2018

1 reference

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Delivery of ubiquitinated substrates to protein-unfolding machines

6 July 2018

1 reference

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The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Structure of the UBA domain of Dsk2p in complex with ubiquitin molecular determinants for ubiquitin recognition.

6 July 2018

1 reference

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Function and regulation of cullin-RING ubiquitin ligases

6 July 2018

1 reference

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Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system

6 July 2018

1 reference

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Nedd8 on cullin: building an expressway to protein destruction.

6 July 2018

1 reference

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Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

The UBX domain: a widespread ubiquitin-like module

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

The von Hippel-Lindau tumor suppressor protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Molecular characterization of the thermosensitive E1 ubiquitin-activating enzyme cell mutant A31N-ts20. Requirements upon different levels of E1 for the ubiquitination/degradation of the various protein substrates in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Identification of NEDD8-conjugation site in human cullin-2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

XPC and human homologs of RAD23: intracellular localization and relationship to other nucleotide excision repair complexes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

A 26 S protease subunit that binds ubiquitin conjugates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Multiple roles of Rbx1 in the VBC-Cul2 ubiquitin ligase complex.

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7007-10-36

Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7007-10-36

Studies on the intracellular localization of hHR23B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7007-10-36

Conjugation to Nedd8 instigates ubiquitylation and down-regulation of activated receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7007-10-36

HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349548

28 October 2018

Identifiers

DOI

10.1186/1741-7007-10-36

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference