(Q34257147)

31 July 2017

title

Cytotoxicity of superoxide dismutase 1 in cultured cells is linked to Zn2+ chelation (English)

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31 July 2017

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Jens Danielsson

7

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author name string

Ann-Sofi Johansson

1

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31 July 2017

Monika Vestling

2

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31 July 2017

Per Zetterström

3

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31 July 2017

Lisa Lang

4

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31 July 2017

Lina Leinartaitė

5

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31 July 2017

Mikael Karlström

6

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31 July 2017

Stefan L Marklund

8

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31 July 2017

Mikael Oliveberg

9

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31 July 2017

language of work or name

English

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publication date

25 April 2012

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31 July 2017

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31 July 2017

volume

7

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31 July 2017

issue

4

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31 July 2017

page(s)

e36104

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

25 April 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Disulfide-reduced ALS variants of Cu, Zn superoxide dismutase exhibit increased populations of unfolded species

6 July 2018

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Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase

6 July 2018

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Cooperation of metallothionein and zinc transporters for regulating zinc homeostasis in human intestinal Caco-2 cells

6 July 2018

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Cysteine 111 affects aggregation and cytotoxicity of mutant Cu,Zn-superoxide dismutase associated with familial amyotrophic lateral sclerosis

6 July 2018

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Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS

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Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

6 July 2018

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Binding of amyloidogenic transthyretin to the plasma membrane alters membrane fluidity and induces neurotoxicity

6 July 2018

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Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants

6 July 2018

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Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis

6 July 2018

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Folding of human superoxide dismutase: disulfide reduction prevents dimerization and produces marginally stable monomers

6 July 2018

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Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis

6 July 2018

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Zn2+ transporters and Zn2+ homeostasis in neurons

6 July 2018

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Accumulation of manganese superoxide dismutase under metal-depleted conditions: proposed role for zinc ions in cellular redox balance

6 July 2018

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Solution structure of Apo Cu,Zn superoxide dismutase: role of metal ions in protein folding

6 July 2018

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Histone Deacetylases: Unique Players in Shaping the Epigenetic Histone Code

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: decreased stability of the apo state

6 July 2018

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Familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase are susceptible to disulfide reduction

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Changing the net charge from negative to positive makes ribonuclease Sa cytotoxic

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Structure and dynamics of copper-free SOD: The protein before binding copper

6 July 2018

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Implication of extracellular zinc exclusion by recombinant human calprotectin (MRP8 and MRP14) from target cells in its apoptosis-inducing activity

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Histone deacetylase inhibitors as new cancer drugs

6 July 2018

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Zinc protects against apoptosis of endothelial cells induced by linoleic acid and tumor necrosis factor alpha

6 July 2018

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Effect of zinc-reversible growth-inhibitory activity in human empyema fluid on antibiotic microbicidal activity

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Metallothionein is part of a zinc-scavenging mechanism for cell survival under conditions of extreme zinc deprivation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

High-affinity zinc inhibition of NMDA NR1-NR2A receptors.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Definition of a continuous human cell line derived from neuroblastoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Contribution of conformational stability and reversibility of unfolding to the increased thermostability of human and bovine superoxide dismutase mutated at free cysteines.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Calorimetric analysis of thermodynamic stability and aggregation for apo and holo amyotrophic lateral sclerosis-associated Gly-93 mutants of superoxide dismutase

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Implications of ALS focality: rostral-caudal distribution of lower motor neuron loss postmortem

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Oxygen-induced maturation of SOD1: a key role for disulfide formation by the copper chaperone CCS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Prefibrillar amyloid aggregates could be generic toxins in higher organisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

The HHQK domain of beta-amyloid provides a structural basis for the immunopathology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Identifying the minimal copper- and zinc-binding site sequence in amyloid-beta peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Fungal susceptibility to zinc deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Different species of alpha-synuclein oligomers induce calcium influx and seeding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Inhibition of Chaperone Activity Is a Shared Property of Several Cu,Zn-Superoxide Dismutase Mutants That Cause Amyotrophic Lateral Sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Cytotoxic actions of the heavy metal chelator TPEN on NG108-15 neuroblastoma-glioma cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338499

Conformational Stability Is a Determinant of Ribonuclease A Cytotoxicity

28 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Backbone Dynamics of Human Cu,Zn Superoxide Dismutase and of Its Monomeric F50E/G51E/E133Q Mutant: The Influence of Dimerization on Mobility and Function†

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036104

Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite

21 January 2018

1 reference

12 December 2020

Amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins

1 reference

12 December 2020

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

1 reference

12 December 2020

Protection by dietary zinc in ALS mutant G93A SOD transgenic mice

1 reference

12 December 2020

Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models

1 reference

12 December 2020

Inclusions of amyotrophic lateral sclerosis-linked superoxide dismutase in ventral horns, liver, and kidney

1 reference

12 December 2020

Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2+

1 reference

12 December 2020

A characterization of copper/zinc superoxide dismutase mutants at position 124. Zinc-deficient proteins

1 reference

12 December 2020

A spectroscopic characterization of a monomeric analog of copper, zinc superoxide dismutase

1 reference

12 December 2020

Cu/Zn superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis

1 reference

12 December 2020

Immunohistochemical study on superoxide dismutases in spinal cords from autopsied patients with amyotrophic lateral sclerosis

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0036104

Identifiers

DOI

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31 July 2017

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31 July 2017

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