(Q57204416)

English

Inhibition of Chaperone Activity Is a Shared Property of Several Cu,Zn-Superoxide Dismutase Mutants That Cause Amyotrophic Lateral Sclerosis

scientific article published in Journal of Biological Chemistry

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Inhibition of chaperone activity is a shared property of several Cu,Zn-superoxide dismutase mutants that cause amyotrophic lateral sclerosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

amyotrophic lateral sclerosis

0 references

molecular chaperones

0 references

Ashutosh Tiwari

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Hemachand Tummala

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Cheolwha Jung

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Zuoshang Xu

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Cynthia M J Higgins

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Lawrence J Hayward

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

0 references

publication date

7 March 2005

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

280

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

18

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

17725-17731

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Mutant dynactin in motor neuron disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Mutations in dynein link motor neuron degeneration to defects in retrograde transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

A missense mutation in Tbce causes progressive motor neuronopathy in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Hindlimb motor neurons require Cu/Zn superoxide dismutase for maintenance of neuromuscular junctions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Cell death after exposure to subarachnoid hemolysate correlates inversely with expression of CuZn-superoxide dismutase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

In vitro photochemical cataract in mice lacking copper-zinc superoxide dismutase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

A familial amyotrophic lateral sclerosis-associated A4V Cu, Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Mutant Cu,Zn superoxide dismutases and familial amyotrophic lateral sclerosis: evaluation of oxidative hypotheses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

No correlation between aggregates of Cu/Zn superoxide dismutase and cell death in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Excitotoxicity hypothesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Aggregate formation in the spinal cord of mutant SOD1 transgenic mice is reversible and mediated by proteasomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Programmed cell death in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Chaperoning brain degeneration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Hsp70 and Hsp40 improve neurite outgrowth and suppress intracytoplasmic aggregate formation in cultured neuronal cells expressing mutant SOD1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Amyotrophic lateral sclerosis: a proposed mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Isolation and characterization of intact mitochondria from neonatal rat brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase are susceptible to disulfide reduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/zinc superoxide dismutase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Molecular chaperones in the cytosol: from nascent chain to folded protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Upregulation of HSP27 in a Transgenic Model of ALS

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

The protein import motor of mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Decrease of Hsp25 protein expression precedes degeneration of motoneurons in ALS-SOD1 mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

ALS, SOD and peroxynitrite

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501705200

21 January 2018

Identifiers

10.1074/JBC.M501705200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753080%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q57204416&oldid=2106168104"