(Q34257246)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22370893%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22370893%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

1 reference

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6

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24 January 2020

author name string

Sandy Leung-Kuen Au

1

1 reference

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24 January 2020

Carmen Chak-Lui Wong

2

1 reference

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24 January 2020

Joyce Man-Fong Lee

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22370893%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Dorothy Ngo-Yin Fan

4

1 reference

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24 January 2020

Felice Hoching Tsang

5

1 reference

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24 January 2020

Chun-Ming Wong

7

1 reference

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24 January 2020

language of work or name

English

0 references

publication date

11 June 2012

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24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22370893%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

volume

56

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22370893%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

page(s)

622-631

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24 January 2020

issue

2

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Global cancer statistics, 2002

24 January 2020

cites work

1 reference

7 January 2021

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7 January 2021

Molecular pathogenesis of hepatocellular carcinoma

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7 January 2021

The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma

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7 January 2021

The polycomb group protein EZH2 is involved in progression of prostate cancer

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7 January 2021

Control of developmental regulators by Polycomb in human embryonic stem cells

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7 January 2021

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

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7 January 2021

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

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7 January 2021

MicroRNAs: target recognition and regulatory functions

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7 January 2021

The diverse functions of microRNAs in animal development and disease

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7 January 2021

Roles of small RNAs in tumor formation

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7 January 2021

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

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7 January 2021

Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer

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7 January 2021

A microRNA DNA methylation signature for human cancer metastasis

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7 January 2021

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

1 reference

7 January 2021

MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

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7 January 2021

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

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7 January 2021

High-throughput tissue microarray analysis of c-myc activation in chronic liver diseases and hepatocellular carcinoma

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7 January 2021

Prognostic significance of pathologic features of hepatocellular carcinoma. A multivariate analysis of 278 patients

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7 January 2021

Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion.

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7 January 2021

The microRNA miR-139 suppresses metastasis and progression of hepatocellular carcinoma by down-regulating Rho-kinase 2.

1 reference

7 January 2021

DIANA-mirPath: Integrating human and mouse microRNAs in pathways

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7 January 2021

SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex

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7 January 2021

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

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7 January 2021

Repression of E-cadherin by the polycomb group protein EZH2 in cancer

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7 January 2021

An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB

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7 January 2021

MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2.

1 reference

7 January 2021

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

1 reference

7 January 2021

RAS is regulated by the let-7 microRNA family

1 reference

7 January 2021

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

1 reference

7 January 2021

MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity

1 reference

7 January 2021

The impact of microRNAs on protein output

1 reference

7 January 2021

Widespread changes in protein synthesis induced by microRNAs

1 reference

7 January 2021

Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma

1 reference

7 January 2021

Rho GTPase-activating protein deleted in liver cancer suppresses cell proliferation and invasion in hepatocellular carcinoma.

1 reference

7 January 2021

Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma

1 reference

7 January 2021

High expression of H3K27me3 in human hepatocellular carcinomas correlates closely with vascular invasion and predicts worse prognosis in patients.

1 reference

7 January 2021

Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma

1 reference

7 January 2021

Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin.

1 reference

7 January 2021

Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells

1 reference

7 January 2021

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

1 reference

7 January 2021

Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

1 reference

7 January 2021