(Q34257253)

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Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure

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31 July 2017

Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure (English)

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31 July 2017

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Faith H Osier

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Katharine A Collins

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Fenella D Halstead

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Fenella D Halstead

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Susanne H Hodgson

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Susanne H Hodgson

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Simon J. Draper

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Simon J Draper

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Adrian V. S. Hill

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Adrian V S Hill

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Kazutoyo Miura

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Carole A Long

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Katie J Ewer

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Kathryn M Milne

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Kathryn H Milne

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Sean C Elias

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Simone C de Cassan

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Simone C de Cassan

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Prateek Choudhary

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Prateek Choudhary

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Sumi Biswas

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Geraldine O'Hara

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Geraldine A O'Hara

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Christopher J A Duncan

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publication date

25 September 2014

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31 July 2017

e107903

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Europe PubMed Central

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31 July 2017

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25 September 2014

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April 2022 Public Data File from Crossref

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Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations

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Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines

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Analysis of human B-cell responses following ChAd63-MVA MSP1 and AMA1 immunization and controlled malaria infection

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Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

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Naturally acquired antibodies specific for Plasmodium falciparum reticulocyte-binding protein homologue 5 inhibit parasite growth and predict protection from malaria

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Utilizing poxviral vectored vaccines for antibody induction-progress and prospects

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Development of chimpanzee adenoviruses as vaccine vectors: challenges and successes emerging from clinical trials.

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Recent advances in antibody-inducing poxviral and adenoviral vectored vaccine delivery platforms for difficult disease targets

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Clinical development of Modified Vaccinia virus Ankara vaccines

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Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination

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Assessment of immune interference, antagonism, and diversion following human immunization with biallelic blood-stage malaria viral-vectored vaccines and controlled malaria infection

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ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans

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Humoral immune responses to a single allele PfAMA1 vaccine in healthy malaria-naïve adults

1 reference

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Early appearance of neutralizing immunoglobulin G3 antibodies is associated with chikungunya virus clearance and long-term clinical protection

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6 July 2018

High affinity antibodies to Plasmodium falciparum merozoite antigens are associated with protection from malaria

1 reference

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6 July 2018

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors

1 reference

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Global malaria mortality between 1980 and 2010: a systematic analysis

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Therapeutic vaccination with recombinant adenovirus reduces splenic parasite burden in experimental visceral leishmaniasis.

1 reference

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Clinical assessment of a recombinant simian adenovirus ChAd63: a potent new vaccine vector

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Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man.

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A viral vectored prime-boost immunization regime targeting the malaria Pfs25 antigen induces transmission-blocking activity

1 reference

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The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

1 reference

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Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177865

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A field trial to assess a blood-stage malaria vaccine

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6 July 2018

Vaccines against malaria

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6 July 2018

Phase Ia clinical evaluation of the Plasmodium falciparum blood-stage antigen MSP1 in ChAd63 and MVA vaccine vectors

1 reference

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The requirement for potent adjuvants to enhance the immunogenicity and protective efficacy of protein vaccines can be overcome by prior immunization with a recombinant adenovirus

1 reference

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6 July 2018

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.

1 reference

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The generation and evaluation of recombinant human IgA specific for Plasmodium falciparum merozoite surface protein 1-19 (PfMSP1 19).

1 reference

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Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1

1 reference

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Immunological responses against Plasmodium falciparum Apical Membrane Antigen 1 vaccines vary depending on the population immunized

1 reference

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Tailoring subunit vaccine immunogenicity: maximizing antibody and T cell responses by using combinations of adenovirus, poxvirus and protein-adjuvant vaccines against Plasmodium falciparum MSP1.

1 reference

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New candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1

1 reference

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Blood-stage malaria vaccines - recent progress and future challenges

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A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray

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6 July 2018

Viruses as vaccine vectors for infectious diseases and cancer

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The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177865

6 July 2018

The carboxy-terminus of merozoite surface protein 1: structure, specific antibodies and immunity to malaria.

1 reference

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6 July 2018

Anti-apical-membrane-antigen-1 antibody is more effective than anti-42-kilodalton-merozoite-surface-protein-1 antibody in inhibiting plasmodium falciparum growth, as determined by the in vitro growth inhibition assay

1 reference

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Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A.

1 reference

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Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya

1 reference

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Recombinant viral vaccines expressing merozoite surface protein-1 induce antibody- and T cell-mediated multistage protection against malaria

1 reference

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Immunoglobulin G subclass-specific responses against Plasmodium falciparum merozoite antigens are associated with control of parasitemia and protection from symptomatic illness

1 reference

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1 reference

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Immunity to malaria: more questions than answers

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1 reference

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Apical membrane antigen 1: a malaria vaccine candidate in review

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Epitope-specific regulation of immunoglobulin class switching in mice immunized with malarial merozoite surface proteins

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177865

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177865

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1 reference

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6 July 2018

Serum antibodies from malaria-exposed people recognize conserved epitopes formed by the two epidermal growth factor motifs of MSP1(19), the carboxy-terminal fragment of the major merozoite surface protein of Plasmodium falciparum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177865

6 July 2018

Kinetic constraints on the development of a malaria vaccine

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Opsonization as an effector mechanism in human protection against asexual blood stages of Plasmodium falciparum: Functional role of IgG subclasses

1 reference

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6 July 2018

Plasmodium falciparum malaria: evidence for an isotype imbalance which may be responsible for delayed acquisition of protective immunity

1 reference

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107903

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107903

21 January 2018

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1 reference

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21 January 2018

The malaria vaccine candidate GMZ2 elicits functional antibodies in individuals from malaria endemic and non-endemic areas

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107903

21 January 2018

Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107903

21 January 2018

Naturally acquired immunoglobulin (Ig)G subclass antibodies to crude asexual Plasmodium falciparum lysates: evidence for association with protection for IgG1 and disease for IgG2.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0107903

21 January 2018

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1 reference

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28 October 2018

Differential effect and interaction of monocytes, hyperimmune sera, and immunoglobulin G on the growth of asexual stage Plasmodium falciparum parasites

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28 October 2018

Pattern of immunoglobulin isotype response to Plasmodium falciparum blood-stage antigens in individuals living in a holoendemic area of Senegal (Dielmo, west Africa).

1 reference

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Immune effector mechanisms in malaria

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A systematic study of neutrophil degranulation and respiratory burst in vitro by defined immune complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25254500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil Fc gamma and complement receptors involved in binding soluble IgG immune complexes and in specific granule release induced by soluble IgG immune complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25254500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic, affinity, and diversity limits of human polyclonal antibody responses against tetanus toxoid

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https://pubmed.ncbi.nlm.nih.gov/25254500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0107903

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2014PLoSO...9j7903B

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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