(Q34258775)

1 August 2017

title

Protein N-terminal acetyltransferases in cancer (English)

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1 August 2017

2

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1 August 2017

T V Kalvik

1

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1 August 2017

language of work or name

English

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publication date

5 March 2012

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1 August 2017

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1 August 2017

volume

32

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1 August 2017

issue

3

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1 August 2017

page(s)

269-276

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Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

N-terminal acetyltransferases and sequence requirements for N-terminal acetylation of eukaryotic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Role of the alpha-amino group of protein in ubiquitin-mediated protein breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

N-terminal acetylation of cellular proteins creates specific degradation signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The N-end rule pathway and regulation by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Nat3p and Mdm20p are required for function of yeast NatB Nalpha-terminal acetyltransferase and of actin and tropomyosin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The stress-induced Tfs1p requires NatB-mediated acetylation to inhibit carboxypeptidase Y and to regulate the protein kinase A pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The recruitment of acetylated and unacetylated tropomyosin to distinct actin polymers permits the discrete regulation of specific myosins in fission yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Golgi targeting of ARF-like GTPase Arl3p requires its Nalpha-acetylation and the integral membrane protein Sys1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane protein Sys1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The yeast orthologue of GRASP65 forms a complex with a coiled-coil protein that contributes to ER to Golgi traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Genome-wide screen for inner nuclear membrane protein targeting in Saccharomyces cerevisiae: roles for N-acetylation and an integral membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

N-terminal acetylation inhibits protein targeting to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Towards a functional understanding of protein N-terminal acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Yeast N(alpha)-terminal acetyltransferases are associated with ribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Bioinformatics analysis of a Saccharomyces cerevisiae N-terminal proteome provides evidence of alternative translation initiation and post-translational N-terminal acetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Identification and specificities of N-terminal acetyltransferases from Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Identification of the human N(alpha)-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Identification and characterization of the human ARD1-NATH protein acetyltransferase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Composition and biological significance of the human Nα-terminal acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

An Nalpha-acetyltransferase responsible for acetylation of the N-terminal residues of histones H4 and H2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Biochemical and structural characterization of recombinant histone acetyltransferase proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Generation of novel monoclonal antibodies and their application for detecting ARD1 expression in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Identification of genes associated with dedifferentiation of hepatocellular carcinoma with expression profiling analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Correlation of expression of human arrest-defective-1 (hARD1) protein with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Analysis of ARD1 function in hypoxia response using retroviral RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Depletion of the human Nα-terminal acetyltransferase A induces p53-dependent apoptosis and p53-independent growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Human arrest defective 1 acetylates and activates beta-catenin, promoting lung cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Arrest defective 1 autoacetylation is a critical step in its ability to stimulate cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

21 January 2018

Cyclin D and oncogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The fundamental role of epigenetic events in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

DNA methylation in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

N-α-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Arrest defective-1 controls tumor cell behavior by acetylating myosin light chain kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Autophagy as a regulated pathway of cellular degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

A genome-wide RNAi screen reveals multiple regulators of caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Cancer cell metabolism: Warburg and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The role of hypoxia-induced factors in tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Hypoxia-inducible factors and hypoxic cell death in tumour physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

HIFs and tumors--causes and consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Tumor hypoxia and cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Hydroxylation of HIF-1: oxygen sensing at the molecular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

HIF-1 and hypoxic response: the plot thickens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Oxygen sensing by HIF hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Targeting HIF-1 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Interaction between HIF-1 alpha (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Purified recombinant hARD1 does not catalyse acetylation of Lys532 of HIF-1alpha fragments in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

NATH, a novel gene overexpressed in papillary thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Tubedown expression correlates with the differentiation status and aggressiveness of neuroblastic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Serological identification and expression analysis of gastric cancer-associated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

LOH analysis of genes around D4S2964 identifies ARD1B as a prognostic predictor of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Implication of human N-alpha-acetyltransferase 5 in cellular proliferation and carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Patt1, a novel protein acetyltransferase that is highly expressed in liver and downregulated in hepatocellular carcinoma, enhances apoptosis of hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

The acetyltransferase activity of San stabilizes the mitotic cohesin at the centromeres in a shugoshin-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Two putative acetyltransferases, san and deco, are required for establishing sister chromatid cohesion in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Differential requirements of a mitotic acetyltransferase in somatic and germ line cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Chromosome segregation and cancer: cutting through the mystery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.82

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.82

1 reference

Dimensions Publication ID

1 August 2017

1022069890

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