(Q34266491)

1 August 2017

1 reference

title

Potential mechanisms of action of lamotrigine in the treatment of bipolar disorders (English)

1 reference

1 August 2017

Potential Mechanisms of Action of Lamotrigine in the Treatment of Bipolar Disorders (English)

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

16 March 2024

1 reference

1

Terence A Ketter

1 reference

1 August 2017

3

Robert M Post

1 reference

1 August 2017

2

Husseini K Manji

1 reference

1 August 2017

language of work or name

English

0 references

publication date

1 October 2003

1 reference

full work available at URL

1 August 2017

https://journals.lww.com/10.1097/01.jcp.0000088915.02635.e8

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Journal of Clinical Psychopharmacology

16 March 2024

published in

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1 August 2017

23

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1 August 2017

5

1 reference

1 August 2017

484-495

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New antiepileptic drugs: comparison of key clinical trials.

1 August 2017

2

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group.

16 March 2024

3

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

A Double-Blind, Placebo-Controlled, Prophylaxis Study of Lamotrigine in Rapid-Cycling Bipolar Disorder

16 March 2024

4

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

A placebo-controlled study of lamotrigine and gabapentin monotherapy in refractory mood disorders

16 March 2024

5

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Cellular and molecular actions of lamotrigine: Possible mechanisms of efficacy in bipolar disorder.

16 March 2024

7

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lack of effect of the novel anticonvulsant SB-204269 on voltage-dependent currents in neurones cultured from rat hippocampus.

16 March 2024

9

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Effects induced by the antiepileptic drug valproic acid upon the ionic currents recorded in rat neocortical neurons in cell culture.

16 March 2024

10

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Positive and negative psychiatric effects of antiepileptic drugs in patients with seizure disorders.

16 March 2024

12

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

16 March 2024

13

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action.

16 March 2024

14

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Effect of carbamazepine, oxcarbazepine and lamotrigine on the increase in extracellular glutamate elicited by veratridine in rat cortex and striatum.

16 March 2024

15

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Inhibition of synaptosomal veratridine-induced sodium influx by antidepressants and neuroleptics used in chronic pain.

16 March 2024

16

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine reduces total postoperative analgesic requirement: a randomized double-blind, placebo-controlled pilot study.

16 March 2024

17

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine (Lamictal) in refractory trigeminal neuralgia: results from a double-blind placebo controlled crossover trial

16 March 2024

18

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Analgesic effects of lamotrigine and phenytoin on cold-induced pain: a crossover placebo-controlled study in healthy volunteers

16 March 2024

19

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

A placebo-controlled trial of lamotrigine for painful HIV-associated neuropathy

16 March 2024

20

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine reduces painful diabetic neuropathy: a randomized, controlled study

16 March 2024

21

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine for central poststroke pain: a randomized controlled trial.

16 March 2024

22

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

200 mg daily of lamotrigine has no analgesic effect in neuropathic pain: a randomised, double-blind, placebo controlled trial

16 March 2024

23

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine may limit pathological excitation in the hippocampus by modulating a transient potassium outward current.

16 March 2024

24

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Preliminary controlled trial of nimodipine in ultra-rapid cycling affective dysregulation

16 March 2024

25

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Nimodipine monotherapy and carbamazepine augmentation in patients with refractory recurrent affective illness.

16 March 2024

26

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Superiority of Lithium Over Verapamil in Mania

16 March 2024

27

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Verapamil for the treatment of acute mania: a double-blind, placebo-controlled trial.

16 March 2024

28

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Voltage-activated calcium channels: targets of antiepileptic drug therapy?

16 March 2024

29

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neurological cultures from rat cortex

16 March 2024

30

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine inhibition of glutamate release from isolated cerebrocortical nerve terminals (synaptosomes) by suppression of voltage-activated calcium channel activity

16 March 2024

31

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

A calcium antagonistic effect of the new antiepileptic drug lamotrigine

16 March 2024

32

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Inhibition of N-type calcium currents by lamotrigine in rat amygdalar neurones

16 March 2024

33

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Presynaptic inhibition of excitatory neurotransmission by lamotrigine in the rat amygdalar neurons.

16 March 2024

34

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine inhibits Ca2+ currents in cortical neurons: functional implications

16 March 2024

35

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons

16 March 2024

36

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

16 March 2024

New antiepileptic drugs

37

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Antiepileptic drugs and mechanisms of epileptogenesis. A review.

16 March 2024

38

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Update on the mechanism of action of antiepileptic drugs

16 March 2024

39

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Felbamate monotherapy has stimulant-like effects in patients with epilepsy.

16 March 2024

42

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Adaptation of cortical NMDA receptors by chronic treatment with specific serotonin reuptake inhibitors.

16 March 2024

44

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Down-regulation of cortical beta-adrenoceptors by chronic treatment with functional NMDA antagonists.

16 March 2024

45

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

1-aminocyclopropanecarboxylates exhibit antidepressant and anxiolytic actions in animal models.

16 March 2024

48

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression

16 March 2024

49

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Alterations in the N-methyl-d-asparatate (NMDA) receptor complex in the frontal cortex of suicide victims

16 March 2024

50

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists.

16 March 2024

51

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Effect of the benzodiazepine receptor antagonist Ro 15-1788 on the anticonvulsant and anticonflict actions of MK-801.

16 March 2024

52

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Anticonflict effects of a competitive NMDA receptor antagonist and a partial agonist at strychnine-insensitive glycine receptors.

16 March 2024

53

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

GABA and mood disorders: a brief review and hypothesis

16 March 2024

55

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study

16 March 2024

56

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy.

16 March 2024

57

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

GABAB receptors are up-regulated by chronic treatment with lithium or carbamazepine. GABA hypothesis of affective disorders?

16 March 2024

58

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

GABA receptor alterations after chronic lithium administration. Comparison with carbamazepine and sodium valproate

16 March 2024

59

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Neurobiologic basis of anxiety and its treatment

16 March 2024

61

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neurological cultures from rat cortex

16 March 2024

63

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Chronic lamotrigine treatment increases rat hippocampal GABA shunt activity and elevates cerebral taurine levels

16 March 2024

64

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine increases gene expression of GABA-A receptor beta3 subunit in primary cultured rat hippocampus cells

16 March 2024

65

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Analysis of CSF amino acids in young patients with generalised refractory epilepsy during an add-on study with lamotrigine.

16 March 2024

66

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Modulation of cerebral GABA by topiramate, lamotrigine, and gabapentin in healthy adults

16 March 2024

67

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study.

16 March 2024

68

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Effects of four antiepileptic drugs on sleep and waking in the rat under both light and dark phases

16 March 2024

70

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

The new antiepileptic drugs: a systematic review of their efficacy and tolerability

16 March 2024

71

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Human Safety of Lamotrigine

16 March 2024

73

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Valproate, lamotrigine, and insulin-mediated risks in women with epilepsy.

16 March 2024

74

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Neuroplasticity and cellular resilience in mood disorders

16 March 2024

76

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Enhancement of hippocampal neurogenesis by lithium

16 March 2024

77

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

16 March 2024

78

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Mood stabilizers, glycogen synthase kinase-3beta and cell survival

16 March 2024

79

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects?

16 March 2024

80

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

N-acetylaspartate in neuropsychiatric disorders

16 March 2024

81

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lithium-induced increase in human brain grey matter

16 March 2024

82

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders

16 March 2024

83

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

3-Acetylpyridine produces age-dependent excitotoxic lesions in rat striatum.

16 March 2024

84

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Felbamate selectively blocks in vitro hippocampal kainate-induced irreversible electrical changes

16 March 2024

85

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

PNU-151774E protects against kainate-induced status epilepticus and hippocampal lesions in the rat.

16 March 2024

86

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Effect of riluzole on quinolinate-induced neuronal damage in rats: comparison with blockers of glutamatergic neurotransmission

16 March 2024

87

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists

16 March 2024

88

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

The novel anticonvulsant lamotrigine prevents dopamine depletion in C57 black mice in the MPTP animal model of Parkinson's disease.

16 March 2024

89

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine inhibits tetraethylammonium-induced synaptic plasticity in the rat amygdala.

16 March 2024

90

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Prevention by lamotrigine, MK-801 and N omega-nitro-L-arginine methyl ester of motoneuron cell death after neonatal axotomy

16 March 2024

91

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine protects hippocampal CA1 neurons from ischemic damage after cardiac arrest.

16 March 2024

92

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Mechanisms of ischaemic damage to central white matter axons: a quantitative histological analysis using rat optic nerve

16 March 2024

93

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Transduction of psychosocial stress into the neurobiology of recurrent affective disorder

16 March 2024

94

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Stressful life events and previous episodes in the etiology of major depression in women: an evaluation of the "kindling" hypothesis

16 March 2024

96

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Genetic risk, number of previous depressive episodes, and stressful life events in predicting onset of major depression

16 March 2024

97

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Clinical consequences of sensitisation in affective disorder:

16 March 2024

98

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Recurrence in affective disorder. I. Case register study.

16 March 2024

99

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

The effect of lamotrigine upon development of cortical kindled seizures in the rat

16 March 2024

101

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine treatment during amygdala-kindled seizure development fails to inhibit seizures and diminishes subsequent anticonvulsant efficacy.

16 March 2024

102

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Effects of lamotrigine and levetiracetam on seizure development in a rat amygdala kindling model

16 March 2024

103

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Tolerance to the anticonvulsant effects of lamotrigine on amygdala kindled seizures: cross-tolerance to carbamazepine but not valproate or diazepam

16 March 2024

104

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Contingent tolerance to the anticonvulsant effects of carbamazepine: relationship to loss of endogenous adaptive mechanisms

16 March 2024

105

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Coadministration of gabapentin or MK-801 with lamotrigine slows tolerance to its anticonvulsant effects on kindled seizures

16 March 2024

106

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine reduces spontaneous and evoked GABAA receptor-mediated synaptic transmission in the basolateral amygdala: implications for its effects in seizure and affective disorders

16 March 2024

107

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders

16 March 2024

108

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats

16 March 2024

109

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Lamotrigine induced selective changes in 5-HT(1A) receptor mediated response in rat brain

16 March 2024

110

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Effects of lamotrigine on the 5-HT1A receptor function in healthy human males.

16 March 2024

111

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Modulation of K+-evoked [3H]-noradrenaline release from rat and human brain slices by gabapentin: involvement of KATP channels

16 March 2024

112

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Emergent properties of networks of biological signaling pathways

16 March 2024

114

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Complexity in biological signaling systems

16 March 2024

115

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Mechanisms of action of anticonvulsants in affective disorders: comparisons with lithium

16 March 2024

116

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Signaling: cellular insights into the pathophysiology of bipolar disorder

16 March 2024

117

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro.

16 March 2024

119

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania

16 March 2024

120

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

Attenuation of cyclic AMP production by carbamazepine.

16 March 2024

121

1 reference

https://api.crossref.org/works/10.1097/01.JCP.0000088915.02635.E8

16 March 2024

Identifiers

1 reference

1 August 2017

1 reference