(Q34268487)

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β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation (English)

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Europe PubMed Central

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1 August 2017

Alzheimer's disease

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Jeffrey H Kordower

11

object named as

Jeffrey H Kordower

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Europe PubMed Central

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1 August 2017

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Yan Cai

1

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1 August 2017

Kun Xiong

2

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1 August 2017

Xue-Mei Zhang

3

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1 August 2017

Huaibin Cai

4

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1 August 2017

Xue-Gang Luo

5

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1 August 2017

Jia-Chun Feng

6

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1 August 2017

Richard W Clough

7

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1 August 2017

Robert G Struble

8

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1 August 2017

Peter R Patrylo

9

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1 August 2017

Yaping Chu

10

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1 August 2017

Xiao-Xin Yan

12

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1 August 2017

language of work or name

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publication date

18 August 2010

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1 August 2017

European Journal of Neuroscience

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1 August 2017

32

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1 August 2017

7

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Europe PubMed Central

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1 August 2017

1223-1238

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Europe PubMed Central

PubMed publication ID

1 August 2017

Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease

1 reference

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Functional deprivation promotes amyloid plaque pathogenesis in Tg2576 mouse olfactory bulb and piriform cortex

1 reference

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6 July 2018

Modeling an anti-amyloid combination therapy for Alzheimer's disease

1 reference

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6 July 2018

The secretases: enzymes with therapeutic potential in Alzheimer disease

1 reference

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6 July 2018

Current treatment and recent clinical research in Alzheimer's disease

1 reference

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6 July 2018

Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development

1 reference

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6 July 2018

Basal cerebral metabolism may modulate the cognitive effects of Abeta in mild cognitive impairment: an example of brain reserve.

1 reference

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6 July 2018

The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential

1 reference

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6 July 2018

Cerebral amyloid angiopathy in the aetiology and immunotherapy of Alzheimer disease

1 reference

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6 July 2018

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

1 reference

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6 July 2018

Is Alzheimer's disease a result of presynaptic failure? Synaptic dysfunctions induced by oligomeric beta-amyloid

1 reference

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6 July 2018

The role of vascular factors in late-onset sporadic Alzheimer's disease. Genetic and molecular aspects.

1 reference

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6 July 2018

Classification and basic pathology of Alzheimer disease

1 reference

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6 July 2018

A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain

1 reference

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6 July 2018

Synaptic transmission block by presynaptic injection of oligomeric amyloid beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

Cortical layer-dependent dynamic blood oxygenation, cerebral blood flow and cerebral blood volume responses during visual stimulation

1 reference

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6 July 2018

Amyloid precursor protein trafficking, processing, and function

1 reference

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6 July 2018

Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease

1 reference

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6 July 2018

Linking vascular disorders and Alzheimer's disease: potential involvement of BACE1

1 reference

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6 July 2018

Mechanisms of amyloid plaque pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

The development of amyloid beta protein deposits in the aged brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

So what if tangles precede plaques?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

An energy budget for signaling in the grey matter of the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

The morphological phenotype of beta-amyloid plaques and associated neuritic changes in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

Cerebrovascular pathology in Alzheimer's disease: cause, effect or epiphenomenon?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

The relationship between senile plaques and cerebral blood vessels in Alzheimer's disease and senile dementia. Morphological mechanism of senile plaque production.

1 reference

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6 July 2018

The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

Aged Non-Human Primates: An Animal Model of Age-Associated Neurodegenerative Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

6 July 2018

Serial reconstruction of β-protein amyloid plaques: relationship to microvessels and size distribution

1 reference

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6 July 2018

Concomitant detection of beta-amyloid peptides with N-terminal truncation and different C-terminal endings in cortical plaques from cases with Alzheimer's disease, senile monkeys and triple transgenic mice.

1 reference

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28 October 2018

Changes with age in the activities of beta-secretase and the Abeta-degrading enzymes neprilysin, insulin-degrading enzyme and angiotensin-converting enzyme.

1 reference

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28 October 2018

BACE1 activity in cerebrospinal fluid and its relation to markers of AD pathology

1 reference

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Oligomeric Abeta in Alzheimer's disease: relationship to plaque and tangle pathology, APOE genotype and cerebral amyloid angiopathy.

1 reference

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Abeta43 is more frequent than Abeta40 in amyloid plaque cores from Alzheimer disease brains.

1 reference

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Consequence of Abeta immunization on the vasculature of human Alzheimer's disease brain.

1 reference

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28 October 2018

Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

28 October 2018

Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment.

1 reference

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28 October 2018

Mitochondrial respiratory inhibition and oxidative stress elevate beta-secretase (BACE1) proteins and activity in vivo in the rat retina.

1 reference

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Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis.

1 reference

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beta-Secretase expression in normal and functionally deprived rat olfactory bulbs: inverse correlation with oxidative metabolic activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

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Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?

1 reference

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Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis.

1 reference

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28 October 2018

Spatial and temporal relationships between plaques and tangles in Alzheimer-pathology.

1 reference

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28 October 2018

The beta-amyloid-related proteins presenilin 1 and BACE1 are axonally transported to nerve terminals in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

28 October 2018

Distribution, progression and chemical composition of cortical amyloid-beta deposits in aged rhesus monkeys: similarities to the human.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

28 October 2018

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

28 October 2018

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

28 October 2018

Stage-correlated distribution of type 1 and 2 dystrophic neurites in cortical and hippocampal plaques in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970759

28 October 2018

Immunoreactivity for GABA plasma membrane transporter, GAT-1, in the developing rat cerebral cortex: transient presence in the somata of neocortical and hippocampal neurons

1 reference

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28 October 2018

Qualitative and Quantitative Differences in Senile Plaque Dystrophie Neurites of Alzheimerʼs Disease and Normal Aged Brain

1 reference

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28 October 2018

Aging in rhesus monkeys: relevance to human health interventions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20726888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NADPH-diaphorase-positive neurons in primate cerebral cortex colocalize with GABA and calcium-binding proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20726888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of normal aging on patterns of local cerebral glucose utilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20726888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1460-9568.2010.07376.X

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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