(Q34269756)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Barbara Stecca

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

R Santini

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

S Pandolfi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

V Montagnani

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

M D'Amico

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

J Y Penachioni

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

M C Vinci

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

L Borgognoni

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

language of work or name

English

0 references

publication date

31 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

4697-4708

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2014.71

12 March 2020

exact match

0 references

cites work

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells

1 reference

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Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Sox2 promotes tamoxifen resistance in breast cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Stem cells and targeted approaches to melanoma cure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

The emerging role of SOX2 in cell proliferation and survival and its crosstalk with oncogenic signaling in lung cancer.

6 July 2018

1 reference

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NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo

6 July 2018

1 reference

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SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression

6 July 2018

1 reference

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WIP1 phosphatase modulates the Hedgehog signaling by enhancing GLI1 function.

6 July 2018

1 reference

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Targeting cancer stem cells: a new therapy to cure cancer patients.

6 July 2018

1 reference

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Melanoma chemotherapy leads to the selection of ABCB5-expressing cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Targeting CD20 in melanoma patients at high risk of disease recurrence.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Regression of metastatic melanoma in a patient by antibody targeting of cancer stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

SOX2 contributes to melanoma cell invasion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function

6 July 2018

1 reference

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SOX2 and nestin expression in human melanoma: an immunohistochemical and experimental study.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Eradication of melanomas by targeted elimination of a minor subset of tumor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Phosphorylation of Sox2 cooperates in reprogramming to pluripotent stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Selection of tumorigenic melanoma cells using ALDH.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

GLI2-mediated melanoma invasion and metastasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Hedgehog controls neural stem cells through p53-independent regulation of Nanog

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

The transcription factor Sox2 is required for osteoblast self-renewal

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Heterogeneous phenotype of human melanoma cells with in vitro and in vivo features of tumor-initiating cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Expression of the embryonic stem cell transcription factor SOX2 in human skin: relevance to melanocyte and merkel cell biology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Identification of cells initiating human melanomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Sonic Hedgehog promotes the development of multipotent neural crest progenitors endowed with both mesenchymal and neural potentials

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Induced pluripotent stem cell lines derived from human somatic cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

A tumorigenic subpopulation with stem cell properties in melanomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

SOX2 functions to maintain neural progenitor identity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Multipotent cell lineages in early mouse development depend on SOX2 function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Gli1 is a target of Sonic hedgehog that induces ventral neural tube development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4180644

Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches.

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

Gli2 is a novel regulator of sox2 expression in telencephalic neuroepithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

Sox2 requirement in sonic hedgehog-associated medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

SOX2 expression associates with stem cell state in human ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

Acetylation of sox2 induces its nuclear export in embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

Identification of a Polyoxometalate Inhibitor of the DNA Binding Activity of Sox2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

Melanoma stem cells: not rare, but well done

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

Sox2 expression in breast tumours and activation in breast cancer stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

Diagnostic utility of neural stem and progenitor cell markers nestin and SOX2 in distinguishing nodal melanocytic nevi from metastatic melanomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.71

31 March 2020

Identifiers

DOI

10.1038/ONC.2014.71

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681955%20AND%20SRC:MED&resulttype=core&format=json