(Q34271138)

English

Galardin (GM 6001), a broad-spectrum matrix metalloproteinase inhibitor, blocks bombesin- and LPA-induced EGF receptor transactivation and DNA synthesis in rat-1 cells

scientific article published on November 1, 2003

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scholarly article

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Europe PubMed Central

1 August 2017

Galardin (GM 6001), a broad-spectrum matrix metalloproteinase inhibitor, blocks bombesin- and LPA-induced EGF receptor transactivation and DNA synthesis in rat-1 cells (English)

1 reference

Europe PubMed Central

1 August 2017

1 reference

ChEBI release 2020-05-28

transcriptional activation

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14568001

23 March 2024

1 reference

10.1016/S0014-4827(03)00355-0

https://api.crossref.org/works/10.1016/S0014-4827(03)00355-0

23 March 2024

author name string

Chintda Santiskulvong

1

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Europe PubMed Central

1 August 2017

Enrique Rozengurt

2

1 reference

Europe PubMed Central

1 August 2017

language of work or name

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publication date

1 November 2003

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Europe PubMed Central

1 August 2017

full work available at URL

https://api.elsevier.com/content/article/PII:S0014482703003550?httpAccept=text/xml

1 reference

10.1016/S0014-4827(03)00355-0

https://api.crossref.org/works/10.1016/S0014-4827(03)00355-0

23 March 2024

https://api.elsevier.com/content/article/PII:S0014482703003550?httpAccept=text/plain

1 reference

10.1016/S0014-4827(03)00355-0

https://api.crossref.org/works/10.1016/S0014-4827(03)00355-0

23 March 2024

Experimental Cell Research

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Europe PubMed Central

1 August 2017

290

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Europe PubMed Central

1 August 2017

2

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Europe PubMed Central

1 August 2017

437-446

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Europe PubMed Central

1 August 2017

Gq and G11 are concurrently activated by bombesin and vasopressin in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Selective reconstitution of gastrin-releasing peptide receptor with G alpha q

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

The bombesin receptor subtypes have distinct G protein specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Temporal relationship between inositol polyphosphate formation and increases in cytosolic Ca2+ in quiescent 3T3 cells stimulated by platelet-derived growth factor, bombesin and vasopressin.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Signal characteristics of G protein-transactivated EGF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Differential modulation of bombesin-stimulated phospholipase C beta and mitogen-activated protein kinase activity by [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Reduced requirement of mitogen-activated protein kinase (MAPK) activity for entry into the S phase of the cell cycle in Swiss 3T3 fibroblasts stimulated by bombesin and insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

[D-Arg1,D-Trp5,7,9,Leu11]Substance P coordinately and reversibly inhibits bombesin- and vasopressin-induced signal transduction pathways in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Rapamycin dissociates p70(S6K) activation from DNA synthesis stimulated by bombesin and insulin in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Differential control of cyclins D1 and D3 and the cdk inhibitor p27Kip1 by diverse signalling pathways in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Galpha(13) stimulates Rho-dependent activation of the cyclooxygenase-2 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Beta-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Transactivation of the epidermal growth factor receptor in colonic epithelial cells by carbachol requires extracellular release of transforming growth factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Heparin blockade of thrombin-induced smooth muscle cell migration involves inhibition of epidermal growth factor (EGF) receptor transactivation by heparin-binding EGF-like growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Angiotensin II signaling and HB-EGF shedding via metalloproteinase in glomerular mesangial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

c-Src phosphorylates epidermal growth factor receptor on tyrosine 845.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Topical synthetic inhibitor of matrix metalloproteinases delays epidermal regeneration of human wounds

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Effect of galardin on collagen degradation by Pseudomonas aeruginosa

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Bombesin and neuromedin B stimulate the activation of p42(mapk) and p74(raf-1) via a protein kinase C-independent pathway in Rat-1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Lysophosphatidic acid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Lysophosphatidic acid, a multifunctional phospholipid messenger

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Lysophosphatidic acid: G-protein signalling and cellular responses

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Lysophospholipids--receptor revelations

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Autophosphorylation sites on the epidermal growth factor receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Neuropeptides as growth factors for normal and cancerous cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Lysophosphatidic acid-regulated mitogenic ERK signaling in androgen-insensitive prostate cancer PC-3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor Shc

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

Dissociation of focal adhesion kinase and paxillin tyrosine phosphorylation induced by bombesin and lysophosphatidic acid from epidermal growth factor receptor transactivation in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900355-0

7 January 2021

The bombesin/GRP receptor transfected into Rat-1 fibroblasts couples to phospholipase C activation, tyrosine phosphorylation of p125FAK and paxillin and cell proliferation

6

1 reference

10.1016/S0014-4827(03)00355-0

https://api.crossref.org/works/10.1016/S0014-4827(03)00355-0

23 March 2024

Inhibition of platelet-derived growth factor and epidermal growth factor receptor signaling events after treatment of cells with specific synthetic inhibitors of tyrosine kinase phosphorylation

45

1 reference

10.1016/S0014-4827(03)00355-0

https://api.crossref.org/works/10.1016/S0014-4827(03)00355-0

23 March 2024

Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation

56

1 reference

10.1016/S0014-4827(03)00355-0

https://api.crossref.org/works/10.1016/S0014-4827(03)00355-0

23 March 2024

Identifiers

10.1016/S0014-4827(03)00355-0

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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