(Q34271192)

1 August 2017

title

Drug repositioning through incomplete bi-cliques in an integrated drug-target-disease network (English)

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1 August 2017

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4

Michael Schroeder

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1 August 2017

Simone Daminelli

1

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1 August 2017

V Joachim Haupt

series ordinal

2

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1 August 2017

Matthias Reimann

series ordinal

3

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1 August 2017

publication date

26 April 2012

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1 August 2017

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1 August 2017

volume

4

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1 August 2017

issue

7

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1 August 2017

page(s)

778-788

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Cutting the cost of drug development?

1 August 2017

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Old friends in new guise: repositioning of known drugs with structural bioinformatics

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Predicting new molecular targets for known drugs

21 January 2018

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Do structurally similar molecules have similar biological activity?

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Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition

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21 January 2018

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Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis

21 January 2018

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A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology

21 January 2018

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Computational polypharmacology with text mining and ontologies

21 January 2018

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Systematic evaluation of drug-disease relationships to identify leads for novel drug uses

21 January 2018

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21 January 2018

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Network pharmacology: the next paradigm in drug discovery

21 January 2018

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Unveiling the role of network and systems biology in drug discovery

21 January 2018

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21 January 2018

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In vitro effect of indomethacin and interferon-alpha on Th1 and Th2 cytokine synthesis in patients with chronic hepatitis C.

21 January 2018

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Chronic inflammation in Alzheimer's disease offers therapeutic opportunities.

21 January 2018

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The flavonoid scaffold as a template for the design of modulators of the vascular Ca(v) 1.2 channels

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Entamoeba histolytica: computer-assisted modeling of phosphofructokinase for the prediction of broad-spectrum antiparasitic agents

21 January 2018

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Trypanocidal activity of the proteasome inhibitor and anti-cancer drug bortezomib

21 January 2018

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Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action?

21 January 2018

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Estrogen and progesterone affect responses to malaria infection in female C57BL/6 mice

21 January 2018

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Synthesis and evaluation of non-peptidic cysteine protease inhibitors of P. falciparum derived from etacrynic acid

21 January 2018

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Antimalarial activity in mice of resveratrol derivative from Pleuropterus ciliinervis

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents

21 January 2018

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21 January 2018

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In vitro antileishmanial activity of resveratrol and its hydroxylated analogues against Leishmania major promastigotes and amastigotes

21 January 2018

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21 January 2018

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21 January 2018

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Antiparasitic activity of risedronate in a murine model of acute Chagas' disease.

21 January 2018

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Radicicol activates heat shock protein expression and cardioprotection in neonatal rat cardiomyocytes

21 January 2018

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Proarrhythmic potential of antimicrobial agents

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

Mechanism of interference by haemolysis in the cardiac troponin T immunoassay

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

Crystal Structure of Cardiac-specific Histone Methyltransferase SmyD1 Reveals Unusual Active Site Architecture

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

Leukotriene A4 hydrolase in the human B-lymphocytic cell line Raji: indications of catalytically divergent forms of the enzyme

21 January 2018

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21 January 2018

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21 January 2018

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Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A₄hydrolase

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

Structural and thermodynamic analysis of thrombin:suramin interaction in solution and crystal phases

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

21 January 2018

The Protein Data Bank

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21 January 2018

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Pybel: a Python wrapper for the OpenBabel cheminformatics toolkit

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

Fold independent structural comparisons of protein-ligand binding sites for exploring functional relationships

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

GoPubMed: exploring PubMed with the Gene Ontology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00154C

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21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2IB00154C

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21 January 2018

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https://api.crossref.org/works/10.1039%2FC2IB00154C

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1039/C2IB00154C

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1 August 2017

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