(Q34271784)

English

Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

David A. Hafler

4

object named as

David A Hafler

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Steven J. Burakoff

3

object named as

Steven J Burakoff

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

author name string

Jacqueline M Slavik

1

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Dong-Gyun Lim

2

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Europe PubMed Central

PubMed publication ID

1 August 2017

language of work or name

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publication date

22 October 2003

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Europe PubMed Central

PubMed publication ID

1 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

1 August 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

910-919

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

1 reference

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21 January 2018

Calcineurin. Structure, function, and inhibition

1 reference

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Mechanism of action of the immunosuppressant rapamycin

1 reference

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Rapamycin in transplantation: a review of the evidence

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Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

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Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes

1 reference

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21 January 2018

Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin

1 reference

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21 January 2018

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

1 reference

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21 January 2018

cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells

1 reference

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21 January 2018

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1 reference

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21 January 2018

Immunopharmacology of rapamycin

1 reference

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21 January 2018

Three-dimensional segregation of supramolecular activation clusters in T cells

1 reference

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21 January 2018

The immunological synapse: a molecular machine controlling T cell activation

1 reference

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Examination of CD8+ T cell function in humans using MHC class I tetramers: similar cytotoxicity but variable proliferation and cytokine production among different clonal CD8+ T cells specific to a single viral epitope

1 reference

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21 January 2018

Determination of lymphocyte division by flow cytometry

1 reference

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21 January 2018

Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

1 reference

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21 January 2018

Rapamycin resistance tied to defective regulation of p27Kip1.

1 reference

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21 January 2018

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

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Evidence that cyclin D1 mediates both growth and proliferation downstream of TOR in hepatocytes

1 reference

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21 January 2018

Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability

1 reference

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21 January 2018

Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts

1 reference

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21 January 2018

IL-2-dependent induction of G1 cyclins in primary T cells is not blocked by rapamycin or cyclosporin A.

1 reference

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21 January 2018

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

The target of rapamycin (TOR) proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

The TOR kinases link nutrient sensing to cell growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation

1 reference

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21 January 2018

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

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21 January 2018

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

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21 January 2018

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

Rapamycin increases the cellular concentration of the BCL-2 protein and exerts an anti-apoptotic effect

1 reference

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21 January 2018

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

Regulation of ribosomal S6 kinase 2 by effectors of the phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209733200

21 January 2018

Erythropoietin activates two distinct signaling pathways required for the initiation and the elongation of c-myc

1 reference

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21 January 2018

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

1 reference

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Cytokine secretion of myelin basic protein reactive T cells in patients with multiple sclerosis

1 reference

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B Cell Growth Is Controlled by Phosphatidylinosotol 3-Kinase-Dependent Induction of Rel/NF-κB Regulated c-myc Transcription

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M209733200

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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