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Removal of shelterin reveals the telomere end-protection problem
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
title
Removal of shelterin reveals the telomere end-protection problem
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
author
Titia de Lange
object named as
Titia de Lange
series ordinal
2
0 references
Agnel Sfeir
series ordinal
1
object named as
Agnel Sfeir
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
language of work or name
English
0 references
publication date
1 May 2012
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
published in
Science
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
volume
336
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
issue
6081
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
page(s)
593-597
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
cites work
Telomere protection by TPP1/POT1 requires tethering to TIN2
1 reference
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PubMed Central
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6 July 2018
DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation
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PubMed Central
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6 July 2018
The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres
1 reference
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PubMed Central
reference URL
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6 July 2018
The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
retrieved
6 July 2018
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
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6 July 2018
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
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PubMed Central
reference URL
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6 July 2018
Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal
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PubMed Central
reference URL
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6 July 2018
Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation
1 reference
stated in
PubMed Central
reference URL
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6 July 2018
Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.
1 reference
stated in
PubMed Central
reference URL
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6 July 2018
Telomere protection by TPP1 is mediated by POT1a and POT1b
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
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6 July 2018
How telomeres solve the end-protection problem
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
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6 July 2018
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
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PubMed Central
reference URL
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6 July 2018
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
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PubMed Central
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6 July 2018
Functional dissection of human and mouse POT1 proteins
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PubMed Central
reference URL
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6 July 2018
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
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6 July 2018
DNA helicases Sgs1 and BLM promote DNA double-strand break resection
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
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6 July 2018
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
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6 July 2018
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
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6 July 2018
4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
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6 July 2018
How shelterin protects mammalian telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
retrieved
6 July 2018
IgH class switching and translocations use a robust non-classical end-joining pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
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6 July 2018
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
retrieved
6 July 2018
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
retrieved
6 July 2018
Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
retrieved
6 July 2018
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
retrieved
6 July 2018
Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
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6 July 2018
Protection of telomeres by the Ku protein in fission yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
retrieved
6 July 2018
The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
retrieved
6 July 2018
Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477646
retrieved
28 October 2018
Yeast Ku as a regulator of chromosomal DNA end structure
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22556254
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1126/SCIENCE.1218498
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
PMCID
3477646
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
PubMed ID
22556254
1 reference
stated in
Europe PubMed Central
PubMed ID
22556254
retrieved
1 August 2017
ResearchGate publication ID
224897522
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