(Q34274294)

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Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ

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31 January 2020

Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ (English)

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31 January 2020

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31 January 2020

Darryl C Zeldin

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31 January 2020

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31 January 2020

Nader G Abraham

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Nader G Abraham

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31 January 2020

Michal Laniado-Schwartzman

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Michal L Schwartzman

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31 January 2020

author name string

Dong Hyun Kim

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31 January 2020

Kazuyoshi Inoue

3

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31 January 2020

Angela Burgess

4

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31 January 2020

Katherine Gotlinger

5

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31 January 2020

Vijaya Lingam Manthati

6

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31 January 2020

Sreenivasulu Reddy Koduru

7

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31 January 2020

publication date

9 October 2010

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31 January 2020

Stem Cells and Development

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31 January 2020

19

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31 January 2020

12

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31 January 2020

1863-1873

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31 January 2020

Improved myocardial perfusion in chronic diabetic mice by the up-regulation of pLKB1 and AMPK signaling.

1 reference

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6 July 2018

AMP-activated protein kinase: a stress-responsive kinase with implications for cardiovascular disease.

1 reference

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6 July 2018

Mesenchymal stromal cells: current understanding and clinical status

1 reference

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6 July 2018

Overexpression of heme oxygenase-1 increases human osteoblast stem cell differentiation.

1 reference

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6 July 2018

HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage

1 reference

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6 July 2018

Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats

1 reference

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6 July 2018

Epoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null mice

1 reference

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6 July 2018

14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Effect of short hairpin RNA-mediated adiponectin/Acrp30 down-regulation on insulin signaling and glucose uptake in the 3T3-L1 adipocytes

1 reference

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6 July 2018

Protective actions of epoxyeicosatrienoic acid: dual targeting of cardiovascular PI3K and KATP channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice

1 reference

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6 July 2018

Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats

1 reference

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6 July 2018

Adipokines, myokines and cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Diabetes impairs the vascular recruitment of normal stem cells by oxidant damage, reversed by increases in pAMPK, heme oxygenase-1, and adiponectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Bone marrow stem cell transplant into intra-bone cavity prevents type 2 diabetes: role of heme oxygenase-adiponectin.

1 reference

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6 July 2018

Hematopoietic mixed chimerism derived from allogeneic embryonic stem cells prevents autoimmune diabetes mellitus in NOD mice.

1 reference

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6 July 2018

Hydrogen peroxide inhibits cytochrome p450 epoxygenases: interaction between two endothelium-derived hyperpolarizing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Targeting endothelial cells with heme oxygenase-1 gene using VE-cadherin promoter attenuates hyperglycemia-mediated cell injury and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Improved cytochemical method for detecting Jordans' bodies in neutral lipid storage diseases

1 reference

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6 July 2018

Arachidonic acid metabolites as endothelium-derived hyperpolarizing factors

1 reference

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6 July 2018

Impact of silencing HO-2 on EC-SOD and the mitochondrial signaling pathway

1 reference

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6 July 2018

Action of epoxyeicosatrienoic acids on cellular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Cardiovascular therapeutic aspects of soluble epoxide hydrolase inhibitors.

1 reference

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6 July 2018

Reactive oxygen species have a causal role in multiple forms of insulin resistance

1 reference

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6 July 2018

Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases

1 reference

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6 July 2018

Separation of insulin signaling into distinct GLUT4 translocation and activation steps

1 reference

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6 July 2018

Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Obesity-induced inflammatory changes in adipose tissue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972407

6 July 2018

Epoxygenase pathways of arachidonic acid metabolism

1 reference

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6 July 2018

Inhibition of adipogenesis by Wnt signaling

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6 July 2018

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1 reference

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6 July 2018

Reactive oxygen species inhibit adhesion of mesenchymal stem cells implanted into ischemic myocardium via interference of focal adhesion complex

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28 October 2018

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1 reference

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28 October 2018

Crucial role for LKB1 to AMPKalpha2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes

1 reference

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28 October 2018

Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells

1 reference

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28 October 2018

Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature.

1 reference

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28 October 2018

Association of soluble epoxide hydrolase gene polymorphism with insulin resistance in type 2 diabetic patients.

1 reference

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28 October 2018

Role of the heme oxygenases in abnormalities of the mesenteric circulation in cirrhotic rats.

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28 October 2018

Vascular dysfunction in hyperglycemia: is protein kinase C the culprit?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20412023

12 December 2020

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Modulation of erythropoiesis by novel human bone marrow cytochrome P450-dependent metabolites of arachidonic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/20412023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of cytochrome P-450 epoxygenase metabolites in EGF signaling in renal proximal tubule

1 reference

https://pubmed.ncbi.nlm.nih.gov/20412023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20412023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20412023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

11,12-epoxyeicosatrienoic acid stimulates heme-oxygenase-1 in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20412023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic suppression of HO-1 exacerbates renal damage: reversed by an increase in the antiapoptotic signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20412023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular dysfunction in hyperglycemia: is protein kinase C the culprit?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20412023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1089/SCD.2010.0098

1 reference

Europe PubMed Central

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31 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20412023%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20412023%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

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