(Q34275400)

1 August 2017

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title

Apoptotic death sensor: an organelle's alter ego? (English)

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1 August 2017

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Bratton SB

1

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1 August 2017

Cohen GM

series ordinal

2

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1 August 2017

publication date

1 June 2001

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Trends in Pharmacological Sciences

1 August 2017

published in

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1 August 2017

volume

22

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1 August 2017

issue

6

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1 August 2017

page(s)

306-315

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Apoptosis in human disease: a new skin for the old ceremony?

1 August 2017

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Caspase structure, proteolytic substrates, and function during apoptotic cell death

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Control of programmed cell death by the baculovirus genes p35 and iap.

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IAP family proteins--suppressors of apoptosis

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7 January 2021

NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

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7 January 2021

NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP

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7 January 2021

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

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7 January 2021

Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

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7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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7 January 2021

Structural basis of IAP recognition by Smac/DIABLO

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7 January 2021

Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

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7 January 2021

The IAP proteins: caspase inhibitors and beyond

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7 January 2021

Molecular mechanisms of apoptosis induced by cytotoxic chemicals

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7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

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7 January 2021

Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex

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7 January 2021

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes

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7 January 2021

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

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7 January 2021

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

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7 January 2021

Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

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7 January 2021

Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex

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7 January 2021

Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1

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7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

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7 January 2021

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

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7 January 2021

BH3-Only proteins-essential initiators of apoptotic cell death

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7 January 2021

Surfing the p53 network

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7 January 2021

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

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7 January 2021

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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7 January 2021

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

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7 January 2021

Bax involvement in p53-mediated neuronal cell death

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7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

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7 January 2021

Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis

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7 January 2021

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

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7 January 2021

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

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7 January 2021

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

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7 January 2021

Death receptors: signaling and modulation

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7 January 2021

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

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7 January 2021

Caspase activation: the induced-proximity model

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7 January 2021

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

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7 January 2021

Induction of apoptosis by cancer chemotherapy.

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7 January 2021

Thymineless death in colon carcinoma cells is mediated via fas signaling

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7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

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7 January 2021

Signal transduction from the endoplasmic reticulum to the cell nucleus

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7 January 2021

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

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7 January 2021

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

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7 January 2021

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

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7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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7 January 2021

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

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7 January 2021

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

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7 January 2021

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901718-1

7 January 2021

Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver

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https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901718-1

7 January 2021

ASK1 is essential for JNK/SAPK activation by TRAF2

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901718-1

7 January 2021

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901718-1

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901718-1

7 January 2021

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

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7 January 2021

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7 January 2021

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7 January 2021

Understanding IAP function and regulation: a view from Drosophila

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https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901718-1

7 January 2021

An emerging blueprint for apoptosis in Drosophila

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https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901718-1

7 January 2021

Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901718-1

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901718-1

7 January 2021

Debcl, a proapoptotic Bcl-2 homologue, is a component of the Drosophila melanogaster cell death machinery.

1 reference

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7 January 2021

A novel activation mechanism of caspase-activated DNase from Drosophila melanogaster

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7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

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7 January 2021

10.1016/S0165-6147(00)01718-1

Identifiers

DOI

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1 August 2017

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