(Q34277020)

English

Pathogen-induced proapoptotic phenotype and high CD95 (Fas) expression accompany a suboptimal CD8+ T-cell response: reversal by adenoviral vaccine.

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2 February 2020

Pathogen-induced proapoptotic phenotype and high CD95 (Fas) expression accompany a suboptimal CD8+ T-cell response: reversal by adenoviral vaccine (English)

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2 February 2020

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Oscar Bruna-Romero

2

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2 February 2020

Mariana R Dominguez

4

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2 February 2020

Jonatan Ersching

5

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2 February 2020

Bruna Cunha de Alencar

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2 February 2020

Ricardo Gazzinelli

8

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2 February 2020

Karina Bortoluci

9

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2 February 2020

Marcela F Lopes

11

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2 February 2020

Gustavo P. Amarante-Mendes

10

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Gustavo P Amarante-Mendes

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2 February 2020

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José Ronnie Vasconcelos

1

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2 February 2020

Adriano F Araújo

3

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2 February 2020

Mauricio M Rodrigues

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2 February 2020

Alexandre V Machado

7

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2 February 2020

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17 May 2012

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2 February 2020

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2 February 2020

8

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2 February 2020

e1002699

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2 February 2020

5

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2 February 2020

copyright license

Creative Commons Attribution 4.0 International

17 May 2012

1 reference

April 2022 Public Data File from Crossref

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Subdominant/cryptic CD8 T cell epitopes contribute to resistance against experimental infection with a human protozoan parasite.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

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Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys

1 reference

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6 July 2018

Heterologous plasmid DNA prime-recombinant human adenovirus 5 boost vaccination generates a stable pool of protective long-lived CD8(+) T effector memory cells specific for a human parasite, Trypanosoma cruzi

1 reference

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Evasion of immune responses by Trypanosoma cruzi, the etiological agent of Chagas disease.

1 reference

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Modulation of CD4+ T-cell activation by CD95 co-stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease

1 reference

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Peptide vaccine induces enhanced tumor growth associated with apoptosis induction in CD8+ T cells

1 reference

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Chagas disease: changes in knowledge and management

1 reference

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6 July 2018

Vector choice determines immunogenicity and potency of genetic vaccines against Angola Marburg virus in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

CD8+ T cells specific for immunodominant trans-sialidase epitopes contribute to control of Trypanosoma cruzi infection but are not required for resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

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Demonstration of cross-protective vaccine immunity against an emerging pathogenic Ebolavirus Species

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Impaired innate immunity in Tlr4(-/-) mice but preserved CD8+ T cell responses against Trypanosoma cruzi in Tlr4-, Tlr2-, Tlr9- or Myd88-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

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Efficacy of multivalent adenovirus-based vaccine against simian immunodeficiency virus challenge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Immunization of mice with a recombinant adenovirus vaccine inhibits the early growth of Mycobacterium tuberculosis after infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Prime-boost immunization with adenoviral and modified vaccinia virus Ankara vectors enhances the durability and polyfunctionality of protective malaria CD8+ T-cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Role of the Fas/FasL pathway in HIV or SIV disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

The role of parasite persistence in pathogenesis of Chagas heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

The importance of apoptosis for immune regulation in Chagas disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Chronic Trypanosoma cruzi-elicited cardiomyopathy: from the discovery to the proposal of rational therapeutic interventions targeting cell adhesion molecules and chemokine receptors--how to make a dream come true

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Back to the future in Chagas disease: from animal models to patient cohort studies, progress in immunopathogenesis research.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Perforin and gamma interferon expression are required for CD4+ and CD8+ T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by heterologous plasmid DNA prime-recombinant adenovirus 5 boost vaccination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

CD8+ T cells in Trypanosoma cruzi infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Insufficient TLR activation contributes to the slow development of CD8+ T cell responses in Trypanosoma cruzi infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

CD95, BIM and T cell homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Regulation of Fas-mediated immune homeostasis by an activation-induced protein, Cyclon.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Intranasal mucosal boosting with an adenovirus-vectored vaccine markedly enhances the protection of BCG-primed guinea pigs against pulmonary tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

New insights on adenovirus as vaccine vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Treatment with anti-FasL antibody preserves memory lymphocytes and virus-specific cellular immunity in macaques challenged with simian immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

CD4 and CD8 T cell responses to the M. tuberculosis Ag85B-TB10.4 promoted by adjuvanted subunit, adenovector or heterologous prime boost vaccination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

The many roles of FAS receptor signaling in the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts

1 reference

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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

1 reference

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Relationship between CD107a expression and cytotoxic activity

1 reference

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6 July 2018

Chagas heart disease pathogenesis: one mechanism or many?

1 reference

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6 July 2018

Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Decoding caspase signaling in host immunity to the protozoan Trypanosoma cruzi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Modulation of CD4(+) T cell-dependent specific cytotoxic CD8(+) T cells differentiation and proliferation by the timing of increase in the pathogen load

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Pathogenesis of chronic Chagas heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Long-term protective immunity induced against Trypanosoma cruzi infection after vaccination with recombinant adenoviruses encoding amastigote surface protein-2 and trans-sialidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

CD8+ T-Cell responses to Trypanosoma cruzi are highly focused on strain-variant trans-sialidase epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Immunogenicity and protection of a recombinant human adenovirus serotype 35-based malaria vaccine against Plasmodium yoelii in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Where do we stand on the autoimmunity hypothesis of Chagas disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Adenovirus vector-based vaccines for human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Inducible nitric oxide synthase is not essential for control of Trypanosoma cruzi infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Chagas disease: a role for autoimmunity?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cell-mediated protective immunity against malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

6 July 2018

Distinct kinetics of effector CD8+ cytotoxic T cells after infection with Trypanosoma cruzi in naive or vaccinated mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

Infection with Trypanosoma cruzi restricts the repertoire of parasite-specific CD8+ T cells leading to immunodominance

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

Strain-specific protective immunity following vaccination against experimental Trypanosoma cruzi infection.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

Pro- and anti-apoptotic CD95 signaling in T cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

Virus-specific CD8 T cells in peripheral tissues are more resistant to apoptosis than those in lymphoid organs.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

Increased CD95/Fas-induced apoptosis of HIV-specific CD8(+) T cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

The replication of human immunodeficiency virus type 1 in macrophages is enhanced after phagocytosis of apoptotic cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

Vaccination with replication-deficient recombinant adenoviruses encoding the main surface antigens of toxoplasma gondii induces immune response and protection against infection in mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002699

21 January 2018

Interleukin-6 (IL-6) prevents activation-induced cell death: IL-2-independent inhibition of Fas/fasL expression and cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

28 October 2018

The Fas death pathway controls coordinated expansions of type 1 CD8 and type 2 CD4 T cells in Trypanosoma cruzi infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

9 December 2018

TLR-dependent induction of IFN-beta mediates host defense against Trypanosoma cruzi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

9 December 2018

Levels of tumor necrosis factor alpha, gamma interferon, and interleukins 4,6, and 10 as determined in mice infected with virulent or attenuated strains of Trypanosoma cruzi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355083

9 December 2018

Interferon alpha augments activation-induced T cell death by upregulation of Fas (CD95/APO-1) and Fas ligand expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22615561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22615561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune response in mice that lack the interferon-gamma receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22615561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22615561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PPAT.1002699

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22615561%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22615561%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22615561%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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