(Q41963150)

14 October 2017

CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling (English)

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14 October 2017

7

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14 October 2017

Klaus-Michael Debatin

10

1 reference

14 October 2017

Tobias L Haas

6

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Nathalie Arhel

object named as

Nathalie Arhel

3

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Frank Kirchhoff

object named as

Frank Kirchhoff

9

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Henning Walczak

8

object named as

Henning Walczak

1 reference

14 October 2017

Gudrun Strauss

1

1 reference

14 October 2017

Jonathan A Lindquist

2

1 reference

14 October 2017

Edward Felder

4

1 reference

14 October 2017

Sabine Karl

5

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14 October 2017

language of work or name

English

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publication date

1 June 2009

1 reference

Journal of Experimental Medicine

14 October 2017

1 reference

14 October 2017

206

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14 October 2017

6

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14 October 2017

1379-1393

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describes a project that uses

14 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2715064/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death

1 reference

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Role of Nef in primate lentiviral immunopathogenesis

5 June 2018

1 reference

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Yes and PI3K bind CD95 to signal invasion of glioblastoma

5 June 2018

1 reference

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Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

5 June 2018

1 reference

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Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.

5 June 2018

1 reference

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Genetic disorders of programmed cell death in the immune system

5 June 2018

1 reference

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MAP kinases in immune responses.

5 June 2018

1 reference

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Cellular FLICE-inhibitory protein is required for T cell survival and cycling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Betulinic acid as new activator of NF-kappaB: molecular mechanisms and implications for cancer therapy

5 June 2018

1 reference

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Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

5 June 2018

1 reference

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Overview of cell death signaling pathways

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Right time, right place: the organization of membrane proximal signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Induction of tolerance using Fas ligand: a double-edged immunomodulator

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Differential regulation of the mitochondrial and death receptor pathways in neural stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

5 June 2018

1 reference

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TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Death receptors couple to both cell proliferation and apoptosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, lymphotoxin-alpha(1)beta(2), Fas ligand, and TNF-related apoptosis-inducing ligand

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Molecular ordering of the initial signaling events of CD95.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

The dual functions of fas ligand in the regulation of peripheral CD8+ and CD4+ T cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Caspase activation is required for T cell proliferation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Antiretroviral cytolytic T-lymphocyte nonresponsiveness: FasL/Fas-mediated inhibition of CD4(+) and CD8(+) antiviral T cells by viral antigen-positive veto cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Membrane compartmentation is required for efficient T cell activation.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

The expression of Fas Ligand by macrophages and its upregulation by human immunodeficiency virus infection.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

A role for FADD in T cell activation and development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Activation of the CD95 (APO-1/Fas) system in T cells from human immunodeficiency virus type-1-infected children.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Mature CD4+ T lymphocytes from MRL/lpr mice are resistant to receptor-mediated tolerance and apoptosis.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Fas transduces activation signals in normal human T lymphocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Fas signaling in thyroid carcinomas is diverted from apoptosis to proliferation.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Impaired activation and localization of LAT in anergic T cells as a consequence of a selective palmitoylation defect.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Lymph node dendritic cells control CD8+ T cell responses through regulated FasL expression

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Lack of FasL-mediated killing leads to in vivo tumor promotion in mouse Lewis lung cancer

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Involvement of SHP-1 tyrosine phosphatase in TCR-mediated signaling pathways in lipid rafts

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Activation interferes with the APO-1 pathway in mature human T cells.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715064

Membrane-bound CD95 ligand expressed on human antigen-presenting cells prevents alloantigen-specific T cell response without impairment of viral and third-party T cell immunity

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20082363

Fas engagement induces neurite growth through ERK activation and p35 upregulation

21 January 2018

1 reference

12 December 2020

T-cell apoptosis and suppression of T-cell receptor/CD3-zeta by Fas ligand-containing membrane vesicles shed from ovarian tumors

1 reference

12 December 2020

The tolerogenic molecule CD95-L is expressed on the plasma membrane of human activated, but not resting, Langerhans' cells

1 reference

12 December 2020

Circulating soluble Fas ligand in patients with gastric carcinoma

1 reference

12 December 2020

Anti-Third Party CD8+ CTLs as Potent Veto Cells

1 reference

12 December 2020

Significance of serum soluble Fas ligand in patients with bladder carcinoma

1 reference

12 December 2020

Apoptosis of mouse naive T cells induced by recombinant soluble Fas ligand and activation-induced resistance to Fas ligand

1 reference

12 December 2020

Tolerance induction by veto CTLs in the TCR transgenic 2C mouse model. II. Deletion of effector cells by Fas-Fas ligand apoptosis

1 reference

12 December 2020

Recombinant anti-CD4 antibody 13B8.2 blocks membrane-proximal events by excluding the Zap70 molecule and downstream targets SLP-76, PLC gamma 1, and Vav-1 from the CD4-segregated Brij 98 detergent-resistant raft domains

1 reference

12 December 2020

Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity

1 reference

12 December 2020

Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL- and CD95L-mediated apoptosis

1 reference

12 December 2020

Targeting the function of mature dendritic cells by human cytomegalovirus: a multilayered viral defense strategy

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20082363

1 reference

14 October 2017

1 reference

14 October 2017

PubMed publication ID

19487421

1 reference