(Q34279676)

English

Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

dehydrogenation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Thomas E. Cheatham, III

2

object named as

Thomas E Cheatham

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

3

object named as

Garold S Yost

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

author name string

Kiumars Shahrokh

1

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Europe PubMed Central

PubMed publication ID

1 August 2017

language of work or name

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publication date

4 June 2012

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Biochimica et Biophysica Acta

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

1820

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

1605-1617

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine

1 reference

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Quantum mechanically derived AMBER-compatible heme parameters for various states of the cytochrome P450 catalytic cycle

1 reference

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1 reference

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Structure and function of cytochromes P450 2B: from mechanism-based inactivators to X-ray crystal structures and back

1 reference

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Structure and mechanism of the complex between cytochrome P4503A4 and ritonavir

1 reference

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1 reference

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1 reference

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1 reference

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Structure-function relationships of estrogenic triphenylethylenes related to endoxifen and 4-hydroxytamoxifen

1 reference

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Hydrocarbon hydroxylation by cytochrome P450 enzymes

1 reference

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Dehydrogenation of the indoline-containing drug 4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (indapamide) by CYP3A4: correlation with in silico predictions

1 reference

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1 reference

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Effect of glutathione on homo- and heterotropic cooperativity in cytochrome P450 3A4.

1 reference

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Cytochrome p450 and chemical toxicology

1 reference

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Metabolism and toxicity of drugs. Two decades of progress in industrial drug metabolism

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State-of-the-art tools for computational site of metabolism predictions: comparative analysis, mechanistical insights, and future applications

1 reference

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What common structural features and variations of mammalian P450s are known to date?

1 reference

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Comparison of multiple Amber force fields and development of improved protein backbone parameters

1 reference

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6 July 2018

Structural basis for ligand promiscuity in cytochrome P450 3A4.

1 reference

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6 July 2018

The ins and outs of cytochrome P450s.

1 reference

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CAVER: a new tool to explore routes from protein clefts, pockets and cavities

1 reference

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6 July 2018

Biomolecular modeling: Goals, problems, perspectives

1 reference

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Three-dimensional models of non-steroidal ligands: a comparative molecular field analysis.

1 reference

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Structures of cytochrome P450 3A4.

1 reference

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Multiple targeting by the antitumor drug tamoxifen: a structure-activity study.

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Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone

1 reference

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1 reference

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based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22677141

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inferred from PubMed ID database lookup

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https://pubmed.ncbi.nlm.nih.gov/22677141

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https://pubmed.ncbi.nlm.nih.gov/22677141

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Identifiers

10.1016/J.BBAGEN.2012.05.011

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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