(Q34280300)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

review article

1 reference

title

Vascular endothelial growth factor and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

0 references

1 reference

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Mohamed Al-Shabrawey

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Ruth B Caldwell

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Manuela Bartoli

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

M Ali Behzadian

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Daniel H Platt

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

R William Caldwell

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

publication date

1 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

Diabetes - Metabolism: Research and Reviews

21 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

442-455

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group

21 December 2019

cites work

1 reference

Factors controlling ocular angiogenesis

21 January 2018

1 reference

Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor

21 January 2018

1 reference

Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization

21 January 2018

1 reference

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

21 January 2018

1 reference

Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1.

21 January 2018

1 reference

Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy

21 January 2018

1 reference

Suppression of diabetic retinopathy with angiopoietin-1.

21 January 2018

1 reference

Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo

21 January 2018

1 reference

Hyperoxia induces retinal vascular endothelial cell apoptosis through formation of peroxynitrite

21 January 2018

1 reference

Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment.

21 January 2018

1 reference

The Wisconsin epidemiologic study of diabetic retinopathy. II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years

21 January 2018

1 reference

7 January 2021

Retinopathy and vision loss in insulin-dependent diabetes in Europe. The EURODIAB IDDM Complications Study

1 reference

7 January 2021

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

1 reference

7 January 2021

Advanced glycation end products increase retinal vascular endothelial growth factor expression

1 reference

7 January 2021

1 reference

7 January 2021

1 reference

7 January 2021

Potential new medical therapies for diabetic retinopathy: protein kinase C inhibitors

1 reference

7 January 2021

Molecular understanding of hyperglycemia's adverse effects for diabetic complications

1 reference

7 January 2021

The potential role of PKC beta in diabetic retinopathy and macular edema

1 reference

7 January 2021

Target molecules for anti-angiogenic therapy: from basic research to clinical trials

1 reference

7 January 2021

Angiogenesis inhibitors revised and revived at AACR

1 reference

7 January 2021

Vascular endothelial growth factor and diabetes: the agonist versus antagonist paradox

1 reference

7 January 2021

Antiangiogenesis agents

1 reference

7 January 2021

Role of vasoactive factors in the pathogenesis of early changes in diabetic retinopathy

1 reference

7 January 2021

Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

1 reference

7 January 2021

Vascular endothelial growth factor in ocular neovascularization and proliferative diabetic retinopathy.

1 reference

7 January 2021

Upregulation of the vascular endothelial growth factor/vascular endothelial growth factor receptor system in experimental background diabetic retinopathy of the rat.

1 reference

7 January 2021

Biochemistry and molecular cell biology of diabetic complications

1 reference

7 January 2021

Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy

1 reference

7 January 2021

Abnormalities of retinal metabolism in diabetes or experimental galactosemia VIII. Prevention by aminoguanidine

1 reference

7 January 2021

Increased H2O2, vascular endothelial growth factor and receptors in the retina of the BBZ/Wor diabetic rat.

1 reference

7 January 2021

Increased NADH oxidase activity in the retina of the BBZ/Wor diabetic rat

1 reference

7 January 2021

Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo

1 reference

7 January 2021

Antioxidants attenuate early up regulation of retinal vascular endothelial growth factor in streptozotocin-diabetic rats

1 reference

7 January 2021

Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine

1 reference

7 January 2021

Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia

1 reference

7 January 2021

Detection of nitrotyrosine in the diabetic plasma: evidence of oxidative stress

1 reference

7 January 2021

High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions.

1 reference

7 January 2021

Role of superoxide anions in changes of endothelial vasoactive response during acute hyperglycemia

1 reference

7 January 2021

Increased superoxide anion formation in endothelial cells during hyperglycemia: an adaptive response or initial step of vascular dysfunction?

1 reference

7 January 2021

High glucose-induced tyrosine nitration in endothelial cells: role of eNOS uncoupling and aldose reductase activation

1 reference

7 January 2021

Peroxynitrite causes DNA damage and oxidation of thiols in rat thymocytes [corrected]

1 reference

7 January 2021

Peroxynitrite causes apoptosis in rat thymocytes

1 reference

7 January 2021

Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells

1 reference

7 January 2021

Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function.

1 reference

7 January 2021

Nitric oxide exposure and sulfhydryl modulation alter L-arginine transport in cultured pulmonary artery endothelial cells

1 reference

7 January 2021

High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H(2) receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endotheli

1 reference

7 January 2021

VEGF receptor signaling in tumor angiogenesis

1 reference

7 January 2021

Role of vascular endothelial growth factor in regulation of physiological angiogenesis

1 reference

7 January 2021

Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

1 reference

7 January 2021

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

1 reference

7 January 2021

Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells

1 reference

7 January 2021

Effects of hypoxia on glial cell expression of angiogenesis-regulating factors VEGF and TGF-beta

1 reference

7 January 2021

Modulation of VEGF production by pH and glucose in retinal Müller cells.

1 reference

7 January 2021

Retinal expression, regulation, and functional bioactivity of prostacyclin-stimulating factor

1 reference

7 January 2021

Thromboxane A(2) regulation of endothelial cell migration, angiogenesis, and tumor metastasis

1 reference

7 January 2021

Correlation of vascular permeability factor/vascular endothelial growth factor with extraretinal neovascularization in the rat

1 reference

7 January 2021

Retinal vascular endothelial growth factor (VEGF) mRNA expression is altered in relation to neovascularization in oxygen induced retinopathy

1 reference

7 January 2021

Detection of vascular endothelial growth factor (VEGF) protein in vascular and non-vascular cells of the normal and oxygen-injured rat retina

1 reference

7 January 2021

Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy

1 reference

7 January 2021

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1 reference

7 January 2021

Post-transcriptional regulation of vascular endothelial growth factor by hypoxia.

1 reference

7 January 2021

Purification and characterization of hypoxia-inducible factor 1

1 reference

7 January 2021

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

1 reference

7 January 2021

Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF.

1 reference

7 January 2021

Induction of vascular endothelial growth factor gene expression by interleukin-1 beta in rat aortic smooth muscle cells

1 reference

7 January 2021

Interleukin 6 induces the expression of vascular endothelial growth factor

1 reference

7 January 2021

Advanced glycation end products induce choroidal endothelial cell proliferation, matrix metalloproteinase-2 and VEGF upregulation in vitro

1 reference

7 January 2021

Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis

1 reference

7 January 2021

The Stat family in cytokine signaling

1 reference

7 January 2021

The role of STATs in proliferation, differentiation, and apoptosis

1 reference

7 January 2021

Preface: STAT signaling

1 reference

7 January 2021

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

1 reference

7 January 2021

Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytes

1 reference

7 January 2021

Cardiac-specific activation of signal transducer and activator of transcription 3 promotes vascular formation in the heart.

1 reference

7 January 2021

Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2).

1 reference

7 January 2021

In vivo activation of JAK2/STAT-3 pathway during angiogenesis induced by GM-CSF.

1 reference

7 January 2021

Vascular endothelial growth factor activates STAT proteins in aortic endothelial cells

1 reference

7 January 2021

VEGF differentially activates STAT3 in microvascular endothelial cells

1 reference

7 January 2021

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

1 reference

7 January 2021

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1 reference

7 January 2021

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1 reference

7 January 2021

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1 reference

7 January 2021

Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization

1 reference

7 January 2021

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

1 reference

7 January 2021

Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family

1 reference

7 January 2021

Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group

1 reference

7 January 2021

Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

1 reference

7 January 2021

Constitutive nitric oxide synthase is associated with retinal vascular permeability in early diabetic rats

1 reference

7 January 2021

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

1 reference

7 January 2021

Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells

1 reference

7 January 2021

Molecular and biological properties of vascular endothelial growth factor

1 reference

7 January 2021

Isolation of putative progenitor endothelial cells for angiogenesis

1 reference

7 January 2021

Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice

1 reference

7 January 2021

Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures

1 reference

7 January 2021

Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis

1 reference

7 January 2021

Advanced glycation end products-driven angiogenesis in vitro. Induction of the growth and tube formation of human microvascular endothelial cells through autocrine vascular endothelial growth factor

1 reference

7 January 2021

Celecoxib, a selective cyclooxygenase-2 inhibitor, inhibits retinal vascular endothelial growth factor expression and vascular leakage in a streptozotocin-induced diabetic rat model

1 reference

7 January 2021

Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression

1 reference

7 January 2021

Outcome of vitreous surgery and the balance between vascular endothelial growth factor and endostatin

1 reference

7 January 2021

Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy

1 reference

7 January 2021

A novel integrin-activated pathway forms PKB/Akt-stimulatory phosphatidylinositol 3,4-bisphosphate via phosphatidylinositol 3-phosphate in platelets

1 reference

7 January 2021

p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells.

1 reference

7 January 2021

Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.

1 reference

7 January 2021

Phosphatidylinositol 3-kinase is a target for protein tyrosine nitration

1 reference

7 January 2021

Characterization of the cytoprotective action of peroxynitrite decomposition catalysts.

1 reference

7 January 2021

Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathology

1 reference

7 January 2021

Effects of intraocular or systemic administration of neutralizing antibody against vascular endothelial growth factor on the murine experimental model of retinopathy

1 reference

7 January 2021

Preclinical and phase 1A clinical evaluation of an anti-VEGF pegylated aptamer (EYE001) for the treatment of exudative age-related macular degeneration

1 reference

7 January 2021

Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer

1 reference

7 January 2021

Soluble Flt-1 gene therapy for peritoneal metastases using HVJ-cationic liposomes

1 reference

7 January 2021

Antiangiogenic gene therapy in a rat glioma model using a dominant-negative vascular endothelial growth factor receptor 2.

1 reference

7 January 2021

Angiozyme: a novel angiogenesis inhibitor

1 reference

7 January 2021

Inhibition of tumor growth, angiogenesis, and microcirculation by the novel Flk-1 inhibitor SU5416 as assessed by intravital multi-fluorescence videomicroscopy

1 reference

7 January 2021

Inhibition of tumor growth and metastasis by targeting tumor-associated angiogenesis with antagonists to the receptors of vascular endothelial growth factor

1 reference

7 January 2021

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

1 reference

7 January 2021

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

1 reference

7 January 2021

Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

1 reference

7 January 2021

Inhibitory mechanism of vascular endothelial growth factor (VEGF) by bucillamine

1 reference

7 January 2021

Inhibitory effects of bucillamine on increased blood-retinal barrier permeability in streptozotocin-induced diabetic rats

1 reference

7 January 2021

Transcription factors as targets for cancer therapy

1 reference

7 January 2021

Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

1 reference

7 January 2021

Effects of statins on the vasculature: Implications for aggressive lipid management in the cardiovascular metabolic syndrome

1 reference

7 January 2021

Beyond lipid lowering: the role of statins in vascular protection

1 reference

7 January 2021

Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes.

1 reference

7 January 2021

Microcirculation as a target for the anti-inflammatory properties of statins.

1 reference

7 January 2021

Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin

1 reference

7 January 2021

Statins have biphasic effects on angiogenesis

1 reference

7 January 2021

Double-edged role of statins in angiogenesis signaling

1 reference

7 January 2021

Fluvastatin enhances the inhibitory effects of a selective angiotensin II type 1 receptor blocker, valsartan, on vascular neointimal formation

1 reference

7 January 2021

Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma. A randomized controlled trial

1 reference

7 January 2021

The role of serum lipids in exudative diabetic maculopathy: is there a place for lipid lowering therapy?

1 reference

7 January 2021

Is diabetic retinopathy an inflammatory disease?

1 reference

7 January 2021

Effects of high glucose concentration and a thromboxane synthase inhibitor on the production of thromboxane A2 and prostaglandin I2 and E2 by cultured retinal endothelial cells

1 reference

7 January 2021

Studies on Salicylates and Complement in Diabetes

1 reference

7 January 2021

Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin

1 reference

7 January 2021

Expression of constitutive cyclo-oxygenase (COX-1) in rats with streptozotocin-induced diabetes; effects of treatment with evening primrose oil or an aldose reductase inhibitor on COX-1 mRNA levels

1 reference

7 January 2021

Oxidative stress and diabetic vascular complications

1 reference

7 January 2021

High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes

1 reference

7 January 2021

Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase

1 reference

7 January 2021

Effect of reinstitution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats

1 reference

7 January 2021

Nitric oxide is proangiogenic in the retina and choroid.

1 reference

7 January 2021

Identifiers

DOI

10.1002/DMRR.415

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14648803%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference