(Q34282379)

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Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A. (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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author name string

Qizhen Shi

1

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Scot A Fahs

2

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Erin L Kuether

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Brian C Cooley

4

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Hartmut Weiler

5

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Europe PubMed Central

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1 August 2017

Robert R Montgomery

6

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1 August 2017

language of work or name

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publication date

6 July 2010

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Europe PubMed Central

PubMed publication ID

1 August 2017

1 reference

Europe PubMed Central

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1 August 2017

116

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Europe PubMed Central

PubMed publication ID

1 August 2017

16

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

3049-3057

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2974610/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Endothelial cell processing and alternatively spliced transcripts of factor VIII: potential implications for coagulation cascades and pulmonary hypertension

1 reference

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High levels of acetylated low-density lipoprotein uptake and low tyrosine kinase with immunoglobulin and epidermal growth factor homology domains-2 (Tie2) promoter activity distinguish sinusoids from other vessel types in murine bone marrow

1 reference

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Molecular and phenotypic determinants of the response to desmopressin in adult patients with mild hemophilia A.

1 reference

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6 July 2018

Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice

1 reference

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6 July 2018

Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity

1 reference

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6 July 2018

Transplanted endothelial cells repopulate the liver endothelium and correct the phenotype of hemophilia A mice

1 reference

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6 July 2018

Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice.

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6 July 2018

Tie2-expressing monocytes: regulation of tumor angiogenesis and therapeutic implications

1 reference

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6 July 2018

Lentivirus-mediated platelet-derived factor VIII gene therapy in murine haemophilia A.

1 reference

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6 July 2018

Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974610

6 July 2018

Regulated release of VWF and FVIII and the biologic implications

1 reference

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6 July 2018

Sustained FVIII expression and phenotypic correction of hemophilia A in neonatal mice using an endothelial-targeted sleeping beauty transposon

1 reference

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6 July 2018

Absence of a desmopressin response after therapeutic expression of factor VIII in hemophilia A dogs with liver-directed neonatal gene therapy

1 reference

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Expression of human factor VIII under control of the platelet-specific alphaIIb promoter in megakaryocytic cell line as well as storage together with VWF.

1 reference

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Heterogeneity of Endothelial Cells from Different Organ Sites in T-Cell Subset Recruitment

1 reference

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Comparative response of plasma VWF in dogs to up-regulation of VWF mRNA by interleukin-11 versus Weibel-Palade body release by desmopressin (DDAVP).

1 reference

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Inducible and selective transgene expression in murine vascular endothelium

1 reference

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6 July 2018

Gene-based approaches to the treatment of hemophilia

1 reference

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6 July 2018

Interactions between von Willebrand factor and Factor VIII: where did they first meet

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A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis

1 reference

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6 July 2018

Intracellular trafficking of factor VIII to von Willebrand factor storage granules

1 reference

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6 July 2018

Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice

1 reference

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Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

1 reference

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Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

1 reference

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Role of the B domain for factor VIII and factor V expression and function.

1 reference

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Synthesis of Antihemophilic Factor Antigen by Cultured Human Endothelial Cells

1 reference

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The effects of epinephrine infusion in patients with von Willebrand's disease

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Effects of AVP and DDAVP on plasma renin activity and electrolyte excretion in conscious dogs

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6 July 2018

Synthesis of Factor VIII Antigen by Cultured Guinea Pig Megakaryocytes

1 reference

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Stabilization of factor VIII in plasma by the von Willebrand factor. Studies on posttransfusion and dissociated factor VIII and in patients with von Willebrand's disease

1 reference

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Activation of human endothelial cells from specific vascular beds induces the release of a FVIII storage pool

1 reference

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Undetected factor VIII in a patient with type 3 von Willebrands disease mistaken as severe haemophilia A.

1 reference

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1 reference

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Lack of desmopressin (DDAVP) response in men with hemophilia A following liver transplantation

1 reference

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1 reference

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1 reference

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Expression of factor VIII by murine liver sinusoidal endothelial cells

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Impact, diagnosis and treatment of von Willebrand disease

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Survival of iodine-125-labeled factor VIII in patients with von Willebrand's disease

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https://pubmed.ncbi.nlm.nih.gov/20606161

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Analysis of Tie receptor tyrosine kinase in haemopoietic progenitor and leukaemia cells

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https://pubmed.ncbi.nlm.nih.gov/20606161

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Epinephrine induces von Willebrand factor release from cultured endothelial cells: involvement of cyclic AMP-dependent signalling in exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20606161

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1 reference

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1 reference

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Identifiers

10.1182/BLOOD-2010-03-272419

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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