(Q36915859)

English

Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity

scientific article published on 21 May 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

0 references

Coagulation factor VIII

0 references

0 references

author name string

Qizhen Shi

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Scot A Fahs

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

David A Wilcox

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Erin L Kuether

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Patricia A Morateck

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Nicole Mareno

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Hartmut Weiler

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Robert R Montgomery

8

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

21 May 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

112

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

2713-2721

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Surgical interventions in a cohort of patients with haemophilia A and inhibitors: an experiential retrospective chart review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Hematopoietic stem-cell gene therapy of hemophilia A incorporating a porcine factor VIII transgene and nonmyeloablative conditioning regimens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Lentivirus-mediated platelet-derived factor VIII gene therapy in murine haemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

An overview of the history, clinical practice concerns, comparative studies and strategies to optimize therapy of bypassing agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Humoral immunity is the dominant barrier for allogeneic bone marrow engraftment in sensitized recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Current European practice in immune tolerance induction therapy in patients with haemophilia and inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Current and future approaches to inhibitor management and aversion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Correction of murine hemophilia A by hematopoietic stem cell gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Absence of a desmopressin response after therapeutic expression of factor VIII in hemophilia A dogs with liver-directed neonatal gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Inhibitors in congenital coagulation disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Pathogenic antibodies to coagulation factors. Part one: factor VIII and factor IX.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Inhibitors in hemophilia A: mechanisms of inhibition, management and perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Recombinant factor VIII expression in hematopoietic cells following lentiviral transduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Immune tolerance induction in patients with haemophilia A with inhibitors: a systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Haemophilias A and B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Development of improved factor VIII molecules and new gene transfer approaches for hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

High level expression of human factor VIII in mammalian cells after retroviral-mediated gene transfer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Hemophilia. Strategies for the treatment of inhibitor patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Properties of anti-factor VIII inhibitor antibodies in hemophilia A patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Advances toward gene therapy for hemophilia at the millennium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Biosynthesis, assembly and secretion of coagulation factor VIII.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Intracellular trafficking of factor VIII to von Willebrand factor storage granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

A practical guide to the evaluation and treatment of hemophilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Myelosuppressive conditioning is required to achieve engraftment of pluripotent stem cells contained in moderate doses of syngeneic bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

29 September 2017

Current use of by-passing agents in Europe in the management of acute bleeds in patients with haemophilia and inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Immune tolerance induction in the treatment of paediatric haemophilia A patients with factor VIII inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Humoral immunity due to long-lived plasma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Effects of irradiation on the in vitro immune response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Incidence of development of factor VIII and factor IX inhibitors in haemophiliacs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

27 June 2018

Ex vivo gene therapy for hemophilia A that enhances safe delivery and sustained in vivo factor VIII expression from lentivirally engineered endothelial progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

High expression reduces an antibody response after neonatal gene therapy with B domain-deleted human factor VIII in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Treatment characteristics and the risk of inhibitor development: a multicenter cohort study among previously untreated patients with severe hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Hematopoietic stem cells encoding porcine factor VIII induce pro-coagulant activity in hemophilia A mice with pre-existing factor VIII immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Efficient AAV1-AAV2 hybrid vector for gene therapy of hemophilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Naked DNA transfer of Factor VIII induced transgene-specific, species-independent immune response in hemophilia A mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Acquired factor VIII inhibitor in a non-haemophilic boy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Efficient production of human FVIII in hemophilic mice using lentiviral vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Definitions in hemophilia. Recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the International Society on Thrombosis and Haemostasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

The abrogation of allosensitization following the induction of mixed allogeneic chimerism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Sustained high-level expression of full-length human factor VIII and restoration of clotting activity in hemophilic mice using a minimal adenovirus vector.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Reaginic antibody formation in the mouse. XI. Participation of long-lived antibody-forming cells in persistent antibody formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Two phases of engraftment established by serial bone marrow transplantation in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556608

4 September 2018

Synthesis of antibody by spleen cells after exposure to kiloroentgen doses of ionizing radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18495954

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Nijmegen modification of the Bethesda assay for factor VIII:C inhibitors: improved specificity and reliability

1 reference

https://pubmed.ncbi.nlm.nih.gov/18495954

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18495954

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiosensitivity of spleen cells from normal and preimmunized mice and its significance to intact animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18495954

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2008-02-138214

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

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