(Q45876434)

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Naked DNA transfer of Factor VIII induced transgene-specific, species-independent immune response in hemophilia A mice

scientific article published in July 2004

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15233948

Naked DNA transfer of Factor VIII induced transgene-specific, species-independent immune response in hemophilia A mice (English)

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15233948

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Coagulation factor VIII

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7

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Hans D Ochs

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15233948

author name string

Peiqing Ye

1

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17 December 2017

http://europepmc.org/abstract/MED/15233948

Arthur R Thompson

2

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17 December 2017

http://europepmc.org/abstract/MED/15233948

Rita Sarkar

3

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17 December 2017

http://europepmc.org/abstract/MED/15233948

Zhenping Shen

4

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17 December 2017

http://europepmc.org/abstract/MED/15233948

David P Lillicrap

5

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17 December 2017

http://europepmc.org/abstract/MED/15233948

Randal J Kaufman

6

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17 December 2017

http://europepmc.org/abstract/MED/15233948

David J Rawlings

8

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17 December 2017

http://europepmc.org/abstract/MED/15233948

Carol H Miao

9

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17 December 2017

http://europepmc.org/abstract/MED/15233948

publication date

1 July 2004

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17 December 2017

http://europepmc.org/abstract/MED/15233948

Molecular Therapy

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17 December 2017

http://europepmc.org/abstract/MED/15233948

10

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17 December 2017

http://europepmc.org/abstract/MED/15233948

1

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17 December 2017

http://europepmc.org/abstract/MED/15233948

117-126

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PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15233948

CD4+ T-cell clones specific for wild-type factor VIII: a molecular mechanism responsible for a higher incidence of inhibitor formation in mild/moderate hemophilia A.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Structure and function of the factor VIII gene and protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Antibodies with hydrolytic activity towards factor VIII in patients with hemophilia A.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Partial correction of murine hemophilia A with neo-antigenic murine factor VIII.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

High-Level Factor VIII Gene ExpressionIn VivoAchieved by Nonviral Liver-Specific Gene Therapy Vectors

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

The canine factor VIII 3'-untranslated region and a concatemeric hepatocyte nuclear factor 1 regulatory element enhance factor VIII transgene expression in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Complete and sustained phenotypic correction of hemophilia B in mice following hepatic gene transfer of a high-expressing human factor IX plasmid

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Inclusion of the hepatic locus control region, an intron, and untranslated region increases and stabilizes hepatic factor IX gene expression in vivo but not in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Long-term and therapeutic-level hepatic gene expression of human factor IX after naked plasmid transfer in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Generation and characterization of E1/E2a/E3/E4-deficient adenoviral vectors encoding human factor VIII.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Muscle-directed gene transfer and transient immune suppression result in sustained partial correction of canine hemophilia B caused by a null mutation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Risk and prevention of anti-factor IX formation in AAV-mediated gene transfer in the context of a large deletion of F9.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Role of vector in activation of T cell subsets in immune responses against the secreted transgene product factor IX.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Influence of vector dose on factor IX-specific T and B cell responses in muscle-directed gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Gene therapy for the hemophilias

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Long-term expression of human coagulation factor VIII and correction of hemophilia A after in vivo retroviral gene transfer in factor VIII-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Nonrandom transduction of recombinant adeno-associated virus vectors in mouse hepatocytes in vivo: cell cycling does not influence hepatocyte transduction

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

In vivo treatment of hemophilia A and mucopolysaccharidosis type VII using nonprimate lentiviral vectors.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia A dogs.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Sustained human factor VIII expression in hemophilia A mice following systemic delivery of a gutless adenoviral vector

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Cross-presentation: a general mechanism for CTL immunity and tolerance

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.04.009

7 January 2021

Identifiers

10.1016/J.YMTHE.2004.04.009

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15233948

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15233948

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