(Q34283057)

English

ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

1 reference

based on heuristic

inferred from title

object named as

Toni Ibrahim

11

0 references

Laura Mercatali

object named as

Laura Mercatali

10

0 references

14

object named as

Connie J Eaves

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

16

object named as

Yibin Kang

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

author name string

Rumela Chakrabarti

1

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Yong Wei

2

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Julie Hwang

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Xiang Hang

4

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Mario Andres Blanco

5

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Abrar Choudhury

6

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Benjamin Tiede

7

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Rose-Anne Romano

8

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Christina DeCoste

9

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Dino Amadori

12

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Nagarajan Kannan

13

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Satrajit Sinha

15

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

publication date

21 September 2014

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Nature Cell Biology

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

16

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

1004-15, 1-13

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Transcription factor Oct1 is a somatic and cancer stem cell determinant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Elf5 inhibits the epithelial–mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Comprehensive molecular portraits of human breast tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Developmental stage and time dictate the fate of Wnt/β-catenin-responsive stem cells in the mammary gland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Cancer stem cells: current status and evolving complexities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Wnt signaling in mammary glands: plastic cell fates and combinatorial signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Dissecting the heterogeneity of triple-negative breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Cancer stem cells: impact, heterogeneity, and uncertainty

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Slug and Sox9 cooperatively determine the mammary stem cell state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

p63 regulates human keratinocyte proliferation via MYC-regulated gene network and differentiation commitment through cell adhesion-related gene network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Frizzled7 as an emerging target for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

FZD7 has a critical role in cell proliferation in triple negative breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

The cell of origin of BRCA1 mutation-associated breast cancer: a cautionary tale of gene expression profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Cells of origin in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

A prophylactic vaccine for breast cancer?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Optimization of duplex stability and terminal asymmetry for shRNA design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Lentiviral vectors to probe and manipulate the Wnt signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

p63 in epithelial survival, germ cell surveillance, and neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

TAp63 induces senescence and suppresses tumorigenesis in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

A mouse mammary epithelial cell model to identify molecular mechanisms regulating breast cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Subtypes of breast cancer show preferential site of relapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Wnt signalling and its impact on development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

p63 and p73 in human cancer: defining the network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

p63 overexpression induces the expression of Sonic Hedgehog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

p63 regulates an adhesion programme and cell survival in epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Generation of a functional mammary gland from a single stem cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Wnt signalling in stem cells and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Wnt signaling and breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Stem cells, cancer, and cancer stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

Lessons from hereditary colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183725

6 July 2018

The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FNCB3040

21 January 2018

Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia

1 reference

https://api.crossref.org/works/10.1038%2FNCB3040

21 January 2018

Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors

1 reference

https://api.crossref.org/works/10.1038%2FNCB3040

21 January 2018

Control of mammary stem cell function by steroid hormone signalling.

1 reference

https://api.crossref.org/works/10.1038%2FNCB3040

21 January 2018

Stable suppression of tumorigenicity by virus-mediated RNA interference

1 reference

https://api.crossref.org/works/10.1038%2FNCB3040

21 January 2018

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

1 reference

https://pubmed.ncbi.nlm.nih.gov/25241036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25241036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer stem cells: an evolving concept

1 reference

https://pubmed.ncbi.nlm.nih.gov/25241036

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NCB3040

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34283057&oldid=2196458556"