(Q34283477)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11407596%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

review article

1 reference

title

Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas (English)

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8 November 2019

1

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8 November 2019

author name string

V W Yong

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11407596%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

publication date

1 February 2001

1 reference

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Journal of Neuro-Oncology

8 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11407596%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

volume

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11407596%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11407596%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

245-264

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Current concepts in neuro-oncology: the cell cycle--a review

8 November 2019

cites work

1 reference

12 December 2020

Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression

1 reference

12 December 2020

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

1 reference

12 December 2020

Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells

1 reference

12 December 2020

Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase C

1 reference

12 December 2020

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

1 reference

12 December 2020

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

1 reference

12 December 2020

Protein kinase C and growth regulation of malignant gliomas.

1 reference

12 December 2020

Comparative analysis of expression of hepatocyte growth factor and its receptor, c-met, in gliomas, meningiomas and schwannomas in humans.

1 reference

12 December 2020

Reverse transcriptase polymerase chain reaction as a reliable method to detect epidermal growth factor receptor exon 2-7 gene deletion in human glioblastomas

1 reference

12 December 2020

Ribozyme inhibition of the protein kinase C alpha triggers apoptosis in glioma cells

1 reference

12 December 2020

Intensification of growth factor receptor signalling by phorbol treatment of ligand-primed cells implies a dimer-stabilizing effect of protein kinase C-dependent juxtamembrane domain phosphorylation

1 reference

12 December 2020

Transforming growth factor-alpha, epidermal growth factor receptor, and proliferating potential in benign and malignant gliomas

1 reference

12 December 2020

A mouse model for glioma: biology, pathology, and therapeutic opportunities.

1 reference

12 December 2020

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

1 reference

12 December 2020

CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas.

1 reference

12 December 2020

Treatment of human glioblastoma cells with the staurosporine derivative CGP 41251 inhibits CDC2 and CDK2 kinase activity and increases radiation sensitivity

1 reference

12 December 2020

Protein kinase C alpha activates RAF-1 by direct phosphorylation

1 reference

12 December 2020

Treatment of recurrent malignant gliomas with chronic oral high-dose tamoxifen.

1 reference

12 December 2020

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

12 December 2020

New functional activities for the p21 family of CDK inhibitors

1 reference

12 December 2020

Multiple infusions of anti-epidermal growth factor receptor (EGFR) monoclonal antibody (EMD 55,900) in patients with recurrent malignant gliomas.

1 reference

12 December 2020

Integrins, oncogenes, and anchorage independence.

1 reference

12 December 2020

Reovirus therapy of tumors with activated Ras pathway

1 reference

12 December 2020

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

12 December 2020

Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities.

1 reference

12 December 2020

Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro

1 reference

12 December 2020

Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q.

1 reference

12 December 2020

Repression of human fibroblast growth factor 2 by a novel transcription factor

1 reference

12 December 2020

Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas

1 reference

12 December 2020

Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation

1 reference

12 December 2020

The retinoblastoma protein and cell cycle control

1 reference

12 December 2020

Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

1 reference

12 December 2020

Rac and Cdc42 are potent stimulators of E2F-dependent transcription capable of promoting retinoblastoma susceptibility gene product hyperphosphorylation

1 reference

12 December 2020

Apoptosis of human glioma cells in vitro and in vivo induced by a neutralizing antibody against human basic fibroblast growth factor.

1 reference

12 December 2020

Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis.

1 reference

12 December 2020

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

1 reference

12 December 2020

Gene amplification in human gliomas

1 reference

12 December 2020

Growth inhibition of astrocytoma cells by farnesyl transferase inhibitors is mediated by a combination of anti-proliferative, pro-apoptotic and anti-angiogenic effects.

1 reference

12 December 2020

Histopathology, classification, and grading of gliomas

1 reference

12 December 2020

Trans receptor inhibition of human glioblastoma cells by erbB family ectodomains.

1 reference

12 December 2020

Human glioblastomas with no alterations of the CDKN2A (p16INK4A, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene

1 reference

12 December 2020

Coexpression of stem cell factor and its receptor c-Kit in human malignant glioma cell lines.

1 reference

12 December 2020

Differential modulation of mitogen-activated protein (MAP) kinase/extracellular signal-related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor

1 reference

12 December 2020

Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors

1 reference

12 December 2020

The autocrine loop of TGF-alpha/EGFR and brain tumors

1 reference

12 December 2020

Recombinant human stem cell factor stimulates growth of a human glioblastoma cell line expressing c-kit protooncogene

1 reference

12 December 2020

PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis

1 reference

12 December 2020

Tumor surveillance via the ARF-p53 pathway.

1 reference

12 December 2020

The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity

1 reference

12 December 2020

Inhibition of glioma cell growth by a truncated platelet-derived growth factor-beta receptor

1 reference

12 December 2020

Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors

1 reference

12 December 2020

Inhibition of the growth of glioblastomas by CGP 41251, an inhibitor of protein kinase C, and by a phorbol ester tumor promoter.

1 reference

12 December 2020

Fibroblast growth factor receptor gene expression and immunoreactivity are elevated in human glioblastoma multiforme

1 reference

12 December 2020

The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells

1 reference

12 December 2020

Increasing complexity of Ras signal transduction: involvement of Rho family proteins

1 reference

12 December 2020

Prostaglandin F2α decreases the affinity of epidermal growth factor receptors in Swiss mouse 3T3 cells via protein kinase C activation

1 reference

12 December 2020

Met and hepatocyte growth factor/scatter factor expression in human gliomas

1 reference

12 December 2020

The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

1 reference

12 December 2020

Increased levels of p21WAF1/Cip1 in human brain tumors.

1 reference

12 December 2020

Antisense expression of protein kinase C alpha inhibits the growth and tumorigenicity of human glioblastoma cells

1 reference

12 December 2020

Analysis of cytokine receptor messenger RNA expression in human glioblastoma cells and normal astrocytes by reverse-transcription polymerase chain reaction

1 reference

12 December 2020

Treatment of glioblastoma U-87 by systemic administration of an antisense protein kinase C-alpha phosphorothioate oligodeoxynucleotide

1 reference

12 December 2020

Basic fibroblast growth factor expression as a predictor of prognosis in pediatric high-grade gliomas.

1 reference

12 December 2020

Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways

1 reference

12 December 2020

Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer.

1 reference

12 December 2020

Expression of retinoblastoma gene product and p21 (WAF1/Cip 1) protein in gliomas: correlations with proliferation markers, p53 expression and survival

1 reference

12 December 2020

Expression of epidermal growth factor receptors in human brain tumors

1 reference

12 December 2020

Gene Amplification in Malignant Human Gliomas: Clinical and Histopathologic Aspects

1 reference

12 December 2020

Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression

1 reference

12 December 2020

The identification of four protein kinase C isoforms in human glioblastoma cell lines: PKC alpha, gamma, epsilon, and zeta

1 reference

12 December 2020

Transforming growth factor-alpha antisense vectors can inhibit glioma cell growth

1 reference

12 December 2020

Regulation of the cell cycle by focal adhesion kinase

1 reference

12 December 2020

Induction of brain tumors in mice using a recombinant platelet-derived growth factor B-chain retrovirus.

1 reference

12 December 2020

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

12 December 2020

Receptor tyrosine kinase expression in astrocytic lesions: similar features in gliosis and glioma

1 reference

12 December 2020

Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors.

1 reference

12 December 2020

Tamoxifen and carboplatin combinational treatment of high-grade gliomas. Results of a clinical trial on newly diagnosed patients.

1 reference

12 December 2020

Activated platelet-derived growth factor autocrine pathway drives the transformed phenotype of a human glioblastoma cell line

1 reference

12 December 2020

Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

1 reference

12 December 2020

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

1 reference

12 December 2020

Efficacy and toxicity of the antisense oligonucleotide aprinocarsen directed against protein kinase C-alpha delivered as a 21-day continuous intravenous infusion in patients with recurrent high-grade astrocytomas

1 reference

12 December 2020

Multiple ras effector pathways contribute to G(1) cell cycle progression

1 reference

12 December 2020

Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide

1 reference

12 December 2020

Lack of p16INK4 or retinoblastoma protein (pRb), or amplification-associated overexpression of cdk4 is observed in distinct subsets of malignant glial tumors and cell lines

1 reference

12 December 2020

Basic science of HER-2/neu: a review

1 reference

12 December 2020

Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas.

1 reference

12 December 2020

Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation

1 reference

12 December 2020

PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.

1 reference

12 December 2020

Function of aberrant EGFR in malignant gliomas

1 reference

12 December 2020

1 reference

12 December 2020

Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity

1 reference

12 December 2020

Expression of c-Met correlates with grade of malignancy in human astrocytic tumours: an immunohistochemical study.

1 reference

12 December 2020

Somatic mutations of PTEN in glioblastoma multiforme.

1 reference

12 December 2020

Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas

1 reference

12 December 2020

Protein kinase C isozymes and substrates

1 reference

12 December 2020

Inhibition of tumor growth by ribozyme-mediated suppression of aberrant epidermal growth factor receptor gene expression.

1 reference

12 December 2020

Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines

1 reference

12 December 2020

Intratumoral infusion of the monoclonal antibody, mAb 425, against the epidermal-growth-factor receptor in patients with advanced malignant glioma.

1 reference

12 December 2020

The proliferative effect of vascular endothelial growth factor requires protein kinase C-alpha and protein kinase C-zeta

1 reference

12 December 2020

The role of protein kinase C (PKC) in the evolution and proliferation of malignant gliomas, and the application of PKC inhibition as a novel approach to anti-glioma therapy

1 reference

12 December 2020

Effects of basic fibroblast growth factor on in vivo cerebral tumorigenesis in rats.

1 reference

12 December 2020

Differential expression of two fibroblast growth factor-receptor genes is associated with malignant progression in human astrocytomas.

1 reference

12 December 2020

Signal transduction for proliferation of glioma cells in vitro occurs predominantly through a protein kinase C-mediated pathway.

1 reference

12 December 2020

Epidermal growth factor receptors: critical mediators of multiple receptor pathways

1 reference

12 December 2020

Differential expression of platelet-derived growth factor receptors in human malignant glioma cell lines.

1 reference

12 December 2020

A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth

1 reference

12 December 2020

A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis

1 reference

12 December 2020

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

12 December 2020

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

1 reference

12 December 2020

Proliferation of human malignant astrocytomas is dependent on Ras activation.

1 reference

12 December 2020

Expression of fibroblast growth factor receptor-1 in human glioma and meningioma tissues

1 reference

12 December 2020

Marked inhibition of glioblastoma target cell tumorigenicity in vitro by retrovirus-mediated transfer of a hairpin ribozyme against deletion-mutant epidermal growth factor receptor messenger RNA.

1 reference

12 December 2020

How do small GTPase signal transduction pathways regulate cell cycle entry?

1 reference

12 December 2020

Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas.

1 reference

12 December 2020

Epigallocathechin-3 gallate selectively inhibits the PDGF-BB-induced intracellular signaling transduction pathway in vascular smooth muscle cells and inhibits transformation of sis-transfected NIH 3T3 fibroblasts and human glioblastoma cells (A172).

1 reference

12 December 2020

Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

1 reference

12 December 2020

The role of integrins in the malignant phenotype of gliomas

1 reference

12 December 2020

Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice

1 reference

12 December 2020

A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis

1 reference

12 December 2020

Platelet-derived growth factor in human glioma

1 reference

12 December 2020

Scatter factor/hepatocyte growth factor expression enhances human glioblastoma tumorigenicity and growth

1 reference

12 December 2020

Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor.

1 reference

12 December 2020

Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells

1 reference

12 December 2020

Antisense epidermal growth factor receptor RNA transfection in human malignant glioma cells leads to inhibition of proliferation and induction of differentiation

1 reference

12 December 2020

Protein kinase C isoforms in human glioblastoma cells

1 reference

12 December 2020

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

1 reference

12 December 2020

Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer

1 reference

12 December 2020

PTEN/MMAC1 mutations and EGFR amplification in glioblastomas.

1 reference

12 December 2020

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops

1 reference

12 December 2020

Growth inhibition induced by Ro 31-8220 and calphostin C in human glioblastoma cell lines is associated with apoptosis and inhibition of CDC2 kinase.

1 reference

12 December 2020

Structural alterations of the epidermal growth factor receptor gene in human gliomas

1 reference

12 December 2020

Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle

1 reference

12 December 2020

Suppression of glioblastoma cell growth following antisense oligonucleotide-mediated inhibition of fibroblast growth factor receptor expression

1 reference

12 December 2020

Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C.

1 reference

12 December 2020

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

1 reference

12 December 2020

Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo.

1 reference

12 December 2020

Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification

1 reference

12 December 2020

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

1 reference

12 December 2020

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

1 reference

12 December 2020

Heparin-binding epidermal growth factor-like growth factor stimulates mitogenic signaling and is highly expressed in human malignant gliomas

1 reference

12 December 2020

Expression of activated epidermal growth factor receptors, Ras-guanosine triphosphate, and mitogen-activated protein kinase in human glioblastoma multiforme specimens

1 reference

12 December 2020

PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas

1 reference

12 December 2020

Molecular pathways in the formation of gliomas.

1 reference

12 December 2020

Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations.

1 reference

12 December 2020

Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas.

1 reference

12 December 2020

Role of protein kinase C isoforms in phorbol ester-induced vascular endothelial growth factor expression in human glioblastoma cells.

1 reference

12 December 2020

Signal transduction by fibroblast growth factor receptors

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1010657030494

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11407596%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 November 2019

1053679311

0 references

1 reference