(Q34285036)

1 August 2017

title

The importance of LAT in the activation, homeostasis, and regulatory function of T cells (English)

1 reference

1 August 2017

The Importance of LAT in the Activation, Homeostasis, and Regulatory Function of T Cells (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.145052

12 July 2024

author name string

Shudan Shen

1

1 reference

1 August 2017

Minghua Zhu

3

1 reference

1 August 2017

Chih-Wen Ou Yang

5

1 reference

1 August 2017

Weiguo Zhang

6

1 reference

1 August 2017

Mariana I. Chuck

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837489

12 July 2024

Deirdre M. Fuller

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837489

12 July 2024

language of work or name

English

0 references

publication date

13 September 2010

1 reference

full work available at URL

1 August 2017

http://www.jbc.org/article/S0021925820468796/pdf

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837489

http://intl.jbc.org/cgi/content/abstract/285/46/35393

12 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837489

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20837489/pdf/?tool=EBI

12 July 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837489

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20837489/?tool=EBI

12 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837489

https://europepmc.org/articles/PMC2975163

12 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837489

https://europepmc.org/articles/PMC2975163?pdf=render

12 July 2024

file format

Portable Document Format

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837489

https://doi.org/10.1074/jbc.m110.145052

12 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20837489

https://api.elsevier.com/content/article/PII:S0021925820468796?httpAccept=text/xml

12 July 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.145052

https://api.elsevier.com/content/article/PII:S0021925820468796?httpAccept=text/plain

12 July 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.145052

https://syndication.highwire.org/content/doi/10.1074/jbc.M110.145052

12 July 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.145052

Journal of Biological Chemistry

12 July 2024

published in

1 reference

1 August 2017

volume

285

1 reference

1 August 2017

issue

46

1 reference

1 August 2017

page(s)

35393-35405

1 reference

The role of the LAT-PLC-gamma1 interaction in T regulatory cell function

1 August 2017

cites work

1 reference

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Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome

6 July 2018

1 reference

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Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking

6 July 2018

1 reference

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Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

6 July 2018

1 reference

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The essential role of LAT in thymocyte development during transition from the double-positive to single-positive stage

6 July 2018

1 reference

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Impaired CD8 T cell memory and CD4 T cell primary responses in IL-7R alpha mutant mice

6 July 2018

1 reference

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Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes

6 July 2018

1 reference

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LAT-mediated signaling in CD4+CD25+ regulatory T cell development

6 July 2018

1 reference

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Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms.

6 July 2018

1 reference

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Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection

6 July 2018

1 reference

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The SLP-76 family of adapter proteins

6 July 2018

1 reference

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Transmembrane adaptor proteins: organizers of immunoreceptor signalling

6 July 2018

1 reference

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Adaptors as central mediators of signal transduction in immune cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Control of regulatory T cell development by the transcription factor Foxp3

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Zap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

How alpha beta T cells deal with induced TCR alpha ablation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

RasGRP is essential for mouse thymocyte differentiation and TCR signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

RasGRP links T-cell receptor signaling to Ras

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Essential role of LAT in T cell development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975163

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

6 July 2018

1 reference

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LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

6 July 2018

1 reference

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Ligand-activated site-specific recombination in mice

6 July 2018

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Inducible site-directed recombination in mouse embryonic stem cells

6 July 2018

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Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) zeta subunit: regulation of TCR-associated protein tyrosine kinase activity by TCR zeta.

6 July 2018

1 reference

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ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

6 July 2018

1 reference

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LAT regulates gammadelta T cell homeostasis and differentiation

6 July 2018

1 reference

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Induction of T helper type 2 immunity by a point mutation in the LAT adaptor

21 January 2018

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A LAT mutation that inhibits T cell development yet induces lymphoproliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

How much TCR does a T cell need?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

TCR signals mediated by Src family kinases are essential for the survival of naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

Negative regulation of T cell activation and autoimmunity by the transmembrane adaptor protein LAB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

Long-Term Survival But Impaired Homeostatic Proliferation of Naive T Cells in the Absence of p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induced expansion of naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145052

Recent immune status determines the source of antigens that drive homeostatic T cell expansion

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20837489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phospho-LAT-independent activation of the ras-mitogen-activated protein kinase pathway: a differential recruitment model of TCR partial agonist signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20837489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

1 August 2017

1 reference

1 August 2017

1 reference